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Items: 1 to 20 of 82

1.
2.

Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination.

Bonacci T, Audebert S, Camoin L, Baudelet E, Iovanna JL, Soubeyran P.

PLoS One. 2017 Jan 18;12(1):e0169988. doi: 10.1371/journal.pone.0169988.

3.

DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis.

Mergner J, Kuster B, Schwechheimer C.

J Biol Chem. 2017 Mar 3;292(9):3854-3865. doi: 10.1074/jbc.M116.767103. Epub 2017 Jan 17.

PMID:
28096463
4.

The Protein Neddylation Pathway in Trypanosoma brucei: FUNCTIONAL CHARACTERIZATION AND SUBSTRATE IDENTIFICATION.

Liao S, Hu H, Wang T, Tu X, Li Z.

J Biol Chem. 2017 Jan 20;292(3):1081-1091. doi: 10.1074/jbc.M116.766741.

PMID:
27956554
5.

Neddylation requires glycyl-tRNA synthetase to protect activated E2.

Mo Z, Zhang Q, Liu Z, Lauer J, Shi Y, Sun L, Griffin PR, Yang XL.

Nat Struct Mol Biol. 2016 Aug;23(8):730-7. doi: 10.1038/nsmb.3250.

6.

PPARγ neddylation essential for adipogenesis is a potential target for treating obesity.

Park HS, Ju UI, Park JW, Song JY, Shin DH, Lee KH, Jeong LS, Yu J, Lee HW, Cho JY, Kim SY, Kim SW, Kim JB, Park KS, Chun YS.

Cell Death Differ. 2016 Aug;23(8):1296-311. doi: 10.1038/cdd.2016.6.

PMID:
26990658
7.

Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway.

Keith SA, Maddux SK, Zhong Y, Chinchankar MN, Ferguson AA, Ghazi A, Fisher AL.

PLoS Genet. 2016 Feb 1;12(2):e1005823. doi: 10.1371/journal.pgen.1005823.

8.

The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair.

Chung D, Dellaire G.

Biomolecules. 2015 Sep 30;5(4):2388-416. doi: 10.3390/biom5042388. Review.

9.

Ubiquitylation, neddylation and the DNA damage response.

Brown JS, Jackson SP.

Open Biol. 2015 Apr;5(4):150018. doi: 10.1098/rsob.150018. Review.

10.

Cycle on Wheels: Is APP Key to the AppBp1 Pathway?

Chen Y, Neve R, Zheng H, Griffin W, Barger S, Mrak R.

Austin Alzheimers Parkinsons Dis. 2014;1(2). pii: id1008.

11.

CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases.

Sharma P, Nag A.

Open Biol. 2014 Feb 12;4:130217. doi: 10.1098/rsob.130217. Review.

12.

Building and remodelling Cullin-RING E3 ubiquitin ligases.

Lydeard JR, Schulman BA, Harper JW.

EMBO Rep. 2013 Dec;14(12):1050-61. doi: 10.1038/embor.2013.173. Review.

13.

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR, Duda DM, Olszewski JL, Hofmann K, Knebel A, Langevin F, Wood N, Wightman M, Schulman BA, Alpi AF.

EMBO J. 2013 Oct 30;32(21):2848-60. doi: 10.1038/emboj.2013.209.

14.

NEDD8 ultimate buster-1 long (NUB1L) protein promotes transfer of NEDD8 to proteasome for degradation through the P97UFD1/NPL4 complex.

Liu S, Yang H, Zhao J, Zhang YH, Song AX, Hu HY.

J Biol Chem. 2013 Oct 25;288(43):31339-49. doi: 10.1074/jbc.M113.484816.

15.

Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display.

Zhao B, Zhang K, Bhuripanyo K, Choi CH, Villhauer EB, Li H, Zheng N, Kiyokawa H, Schindelin H, Yin J.

PLoS One. 2013 Aug 1;8(8):e70312. doi: 10.1371/journal.pone.0070312.

16.

Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade.

Zhao B, Zhang K, Villhauer EB, Bhuripanyo K, Kiyokawa H, Schindelin H, Yin J.

Chembiochem. 2013 Jul 22;14(11):1323-30. doi: 10.1002/cbic.201300234.

17.

Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response.

Takashima O, Tsuruta F, Kigoshi Y, Nakamura S, Kim J, Katoh MC, Fukuda T, Irie K, Chiba T.

PLoS One. 2013;8(3):e58911. doi: 10.1371/journal.pone.0058911.

18.

DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.

Heir P, Sufan RI, Greer SN, Poon BP, Lee JE, Ohh M.

Mol Cell Biol. 2013 Apr;33(8):1621-31. doi: 10.1128/MCB.01342-12.

19.
20.

A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.

Toth JI, Yang L, Dahl R, Petroski MD.

Cell Rep. 2012 Apr 19;1(4):309-16. doi: 10.1016/j.celrep.2012.02.006.

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