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Items: 1 to 20 of 134


Mutations in TUBB4B Cause a Distinctive Sensorineural Disease.

Luscan R, Mechaussier S, Paul A, Tian G, Gérard X, Defoort-Dellhemmes S, Loundon N, Audo I, Bonnin S, LeGargasson JF, Dumont J, Goudin N, Garfa-Traoré M, Bras M, Pouliet A, Bessières B, Boddaert N, Sahel JA, Lyonnet S, Kaplan J, Cowan NJ, Rozet JM, Marlin S, Perrault I.

Am J Hum Genet. 2017 Dec 7;101(6):1006-1012. doi: 10.1016/j.ajhg.2017.10.010. Epub 2017 Nov 30.


Deficiency of spermatogenesis and reduced expression of spermatogenesis-related genes in prefoldin 5-mutant mice.

Yamane T, Shimizu T, Takahashi-Niki K, Takekoshi Y, Iguchi-Ariga SMM, Ariga H.

Biochem Biophys Rep. 2015 Mar 24;1:52-61. doi: 10.1016/j.bbrep.2015.03.005. eCollection 2015 May.


A proteome view of structural, functional, and taxonomic characteristics of major protein domain clusters.

Sun CT, Chiang AWT, Hwang MJ.

Sci Rep. 2017 Oct 27;7(1):14210. doi: 10.1038/s41598-017-13297-0.


Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium.

An YJ, Rowland SE, Na JH, Spigolon D, Hong SK, Yoon YJ, Lee JH, Robb FT, Cha SS.

Nat Commun. 2017 Oct 10;8(1):827. doi: 10.1038/s41467-017-00980-z.


Nucleotide Binding to ARL2 in the TBCD∙ARL2∙β-Tubulin Complex Drives Conformational Changes in β-Tubulin.

Francis JW, Goswami D, Novick SJ, Pascal BD, Weikum ER, Ortlund EA, Griffin PR, Kahn RA.

J Mol Biol. 2017 Nov 24;429(23):3696-3716. doi: 10.1016/j.jmb.2017.09.016. Epub 2017 Sep 29.


The human cytoplasmic dynein interactome reveals novel activators of motility.

Redwine WB, DeSantis ME, Hollyer I, Htet ZM, Tran PT, Swanson SK, Florens L, Washburn MP, Reck-Peterson SL.

Elife. 2017 Jul 18;6. pii: e28257. doi: 10.7554/eLife.28257.


R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

Cloutier P, Poitras C, Durand M, Hekmat O, Fiola-Masson É, Bouchard A, Faubert D, Chabot B, Coulombe B.

Nat Commun. 2017 May 31;8:15615. doi: 10.1038/ncomms15615.


Shaping proteostasis at the cellular, tissue, and organismal level.

Sala AJ, Bott LC, Morimoto RI.

J Cell Biol. 2017 May 1;216(5):1231-1241. doi: 10.1083/jcb.201612111. Epub 2017 Apr 11. Review.


Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae.

Plateau P, Saveanu C, Lestini R, Dauplais M, Decourty L, Jacquier A, Blanquet S, Lazard M.

Sci Rep. 2017 Mar 17;7:44761. doi: 10.1038/srep44761.


Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic Mutant Counterparts.

Conway de Macario E, Robb FT, Macario AJ.

Front Mol Biosci. 2017 Jan 9;3:84. doi: 10.3389/fmolb.2016.00084. eCollection 2016. Review.


Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells.

Rodolfo C, Rocco M, Cattaneo L, Tartaglia M, Sassi M, Aducci P, Scaloni A, Camoni L, Marra M.

PLoS One. 2016 Dec 9;11(12):e0167672. doi: 10.1371/journal.pone.0167672. eCollection 2016.


Prefoldin 1 promotes EMT and lung cancer progression by suppressing cyclin A expression.

Wang D, Shi W, Tang Y, Liu Y, He K, Hu Y, Li J, Yang Y, Song J.

Oncogene. 2017 Feb 16;36(7):885-898. doi: 10.1038/onc.2016.257. Epub 2016 Oct 3.


The Genetics of Leaf Flecking in Maize and Its Relationship to Plant Defense and Disease Resistance.

Olukolu BA, Bian Y, De Vries B, Tracy WF, Wisser RJ, Holland JB, Balint-Kurti PJ.

Plant Physiol. 2016 Nov;172(3):1787-1803. Epub 2016 Sep 26.


The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases.

Pérez C, Pérez-Zúñiga FJ, Garrido F, Reytor E, Portillo F, Pajares MA.

PLoS One. 2016 Aug 22;11(8):e0161672. doi: 10.1371/journal.pone.0161672. eCollection 2016. Erratum in: PLoS One. 2016;11(9):e0163761.


Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility.

Comyn SA, Young BP, Loewen CJ, Mayor T.

PLoS Genet. 2016 Jul 22;12(7):e1006184. doi: 10.1371/journal.pgen.1006184. eCollection 2016 Jul.


A genome-wide imaging-based screening to identify genes involved in synphilin-1 inclusion formation in Saccharomyces cerevisiae.

Zhao L, Yang Q, Zheng J, Zhu X, Hao X, Song J, Lebacq T, Franssens V, Winderickx J, Nystrom T, Liu B.

Sci Rep. 2016 Jul 21;6:30134. doi: 10.1038/srep30134.


Replacement of GroEL in Escherichia coli by the Group II Chaperonin from the Archaeon Methanococcus maripaludis.

Shah R, Large AT, Ursinus A, Lin B, Gowrinathan P, Martin J, Lund PA.

J Bacteriol. 2016 Sep 9;198(19):2692-700. doi: 10.1128/JB.00317-16. Print 2016 Oct 1.


p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability.

Han A, Li J, Li Y, Wang Y, Bergholz J, Zhang Y, Li C, Xiao ZhX.

Oncotarget. 2016 Jul 12;7(28):44277-44287. doi: 10.18632/oncotarget.10187. Erratum in: Oncotarget. 2017 Jun 13;8(24):39935.


Mutations in TUBB8 cause a multiplicity of phenotypes in human oocytes and early embryos.

Feng R, Yan Z, Li B, Yu M, Sang Q, Tian G, Xu Y, Chen B, Qu R, Sun Z, Sun X, Jin L, He L, Kuang Y, Cowan NJ, Wang L.

J Med Genet. 2016 Oct;53(10):662-71. doi: 10.1136/jmedgenet-2016-103891. Epub 2016 Jun 6.


Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1.

Lipinski KA, Britschgi C, Schrader K, Christinat Y, Frischknecht L, Krek W.

Oncotarget. 2016 May 17;7(20):29635-47. doi: 10.18632/oncotarget.8816.

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