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Items: 1 to 20 of 263

1.

Evidence for a pre-malignant cell line in a skin biopsy from a patient with Nijmegen breakage syndrome.

Habib R, Neitzel H, Ernst A, Wong JKL, Goryluk-Kozakiewicz B, Gerlach A, Demuth I, Sperling K, Chrzanowska K.

Mol Cytogenet. 2018 Feb 7;11:17. doi: 10.1186/s13039-018-0364-6. eCollection 2018.

2.

A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair.

Boswell ZK, Rahman S, Canny MD, Latham MP.

Sci Rep. 2018 Jan 26;8(1):1639. doi: 10.1038/s41598-018-19908-8.

3.

The impact of recombination on human mutation load and disease.

Alves I, Houle AA, Hussin JG, Awadalla P.

Philos Trans R Soc Lond B Biol Sci. 2017 Dec 19;372(1736). pii: 20160465. doi: 10.1098/rstb.2016.0465. Review.

PMID:
29109227
4.

Identification of ATIC as a Novel Target for Chemoradiosensitization.

Liu X, Paila UD, Teraoka SN, Wright JA, Huang X, Quinlan AR, Gatti RA, Concannon P.

Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):162-173. doi: 10.1016/j.ijrobp.2017.08.033. Epub 2017 Sep 21.

PMID:
29029884
5.

Quantitative Phosphoproteomic Analysis Reveals Key Mechanisms of Cellular Proliferation in Liver Cancer Cells.

Zhu B, He Q, Xiang J, Qi F, Cai H, Mao J, Zhang C, Zhang Q, Li H, Lu L, Wang T, Yu W.

Sci Rep. 2017 Sep 7;7(1):10908. doi: 10.1038/s41598-017-10716-0.

6.

Identifying technology innovations for marginalized smallholders-A conceptual approach.

Malek MA, Gatzweiler FW, Von Braun J.

Technol Soc. 2017 May;49:48-56. doi: 10.1016/j.techsoc.2017.03.002.

7.

Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.

Li Y, Wang J, Zhou G, Lajeunesse M, Le N, Stawicki BN, Corcino YL, Berkner KL, Runge KW.

Genetics. 2017 May;206(1):481-496. doi: 10.1534/genetics.117.200972. Epub 2017 Mar 14.

PMID:
28292918
8.

DNA damage response is hijacked by human papillomaviruses to complete their life cycle.

Hong SY.

J Zhejiang Univ Sci B. 2017 Mar.;18(3):215-232. doi: 10.1631/jzus.B1600306. Review.

9.

Biological determinants of radioresistance and their remediation in pancreatic cancer.

Seshacharyulu P, Baine MJ, Souchek JJ, Menning M, Kaur S, Yan Y, Ouellette MM, Jain M, Lin C, Batra SK.

Biochim Biophys Acta. 2017 Aug;1868(1):69-92. doi: 10.1016/j.bbcan.2017.02.003. Epub 2017 Feb 27. Review.

PMID:
28249796
10.

Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.

Henrich SM, Usadel C, Werwein E, Burdova K, Janscak P, Ferrari S, Hess D, Klempnauer KH.

Sci Rep. 2017 Jan 27;7:41663. doi: 10.1038/srep41663.

11.

The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.

Kim JH, Grosbart M, Anand R, Wyman C, Cejka P, Petrini JH.

Cell Rep. 2017 Jan 10;18(2):496-507. doi: 10.1016/j.celrep.2016.12.035.

12.

Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.

Moniz LS, Surinova S, Ghazaly E, Velasco LG, Haider S, Rodríguez-Prados JC, Berenjeno IM, Chelala C, Vanhaesebroeck B.

Sci Rep. 2017 Jan 6;7:39985. doi: 10.1038/srep39985.

13.

The Slavic NBN Founder Mutation: A Role for Reproductive Fitness?

Seemanova E, Varon R, Vejvalka J, Jarolim P, Seeman P, Chrzanowska KH, Digweed M, Resnick I, Kremensky I, Saar K, Hoffmann K, Dutrannoy V, Karbasiyan M, Ghani M, Barić I, Tekin M, Kovacs P, Krawczak M, Reis A, Sperling K, Nothnagel M.

PLoS One. 2016 Dec 9;11(12):e0167984. doi: 10.1371/journal.pone.0167984. eCollection 2016.

14.

T-lymphoblastic leukemia/lymphoma in macedonian patients with Nijmegen breakage syndrome.

Kocheva SA, Martinova K, Antevska-Trajkova Z, Coneska-Jovanova B, Eftimov A, Dimovski AJ.

Balkan J Med Genet. 2016 Aug 2;19(1):91-94. eCollection 2016 Jul 1.

15.

Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex.

Oh J, Al-Zain A, Cannavo E, Cejka P, Symington LS.

Mol Cell. 2016 Oct 20;64(2):405-415. doi: 10.1016/j.molcel.2016.09.011. Epub 2016 Oct 13.

16.

Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome.

Kuwano Y, Nishida K, Akaike Y, Kurokawa K, Nishikawa T, Masuda K, Rokutan K.

Int J Mol Sci. 2016 Sep 27;17(10). pii: E1638. Review.

17.

Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?

Wang H, Dharmalingam P, Vasquez V, Mitra J, Boldogh I, Rao KS, Kent TA, Mitra S, Hegde ML.

Mech Ageing Dev. 2017 Jan;161(Pt A):163-176. doi: 10.1016/j.mad.2016.09.005. Epub 2016 Sep 20. Review.

18.

Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors.

Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock CJ, Li C, Lee BJ, Loredan DG, Jiang W, Vindigni A, Wang D, Rabadan R, Zha S.

Elife. 2016 Jun 15;5. pii: e14709. doi: 10.7554/eLife.14709.

19.

Mechanism and regulation of DNA end resection in eukaryotes.

Symington LS.

Crit Rev Biochem Mol Biol. 2016 May-Jun;51(3):195-212. doi: 10.3109/10409238.2016.1172552. Epub 2016 Apr 20. Review.

20.

NBS1 and multiple regulations of DNA damage response.

Komatsu K.

J Radiat Res. 2016 Aug;57 Suppl 1:i11-i17. doi: 10.1093/jrr/rrw031. Epub 2016 Apr 10. Review.

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