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Items: 1 to 20 of 44

1.

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.

Fischbach A, Krüger A, Hampp S, Assmann G, Rank L, Hufnagel M, Stöckl MT, Fischer JMF, Veith S, Rossatti P, Ganz M, Ferrando-May E, Hartwig A, Hauser K, Wiesmüller L, Bürkle A, Mangerich A.

Nucleic Acids Res. 2018 Jan 25;46(2):804-822. doi: 10.1093/nar/gkx1205.

2.

Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors.

Cseh AM, Fábián Z, Sümegi B, Scorrano L.

Oncotarget. 2017 Jul 25;8(30):50221-50239. doi: 10.18632/oncotarget.16859. Review.

3.

Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.

Okuda A, Kurokawa S, Takehashi M, Maeda A, Fukuda K, Kubo Y, Nogusa H, Takatani-Nakase T, Okuda S, Ueda K, Tanaka S.

BMC Neurosci. 2017 Jan 17;18(1):14. doi: 10.1186/s12868-016-0333-0.

4.

PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway.

Kishi Y, Fujihara H, Kawaguchi K, Yamada H, Nakayama R, Yamamoto N, Fujihara Y, Hamada Y, Satomura K, Masutani M.

Int J Mol Sci. 2015 Oct 19;16(10):24820-38. doi: 10.3390/ijms161024820.

5.

Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis.

Jiang BH, Tseng WL, Li HY, Wang ML, Chang YL, Sung YJ, Chiou SH.

Int J Mol Sci. 2015 Jul 9;16(7):15531-45. doi: 10.3390/ijms160715531. Review.

6.

5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme.

Ciccarone F, Valentini E, Zampieri M, Caiafa P.

Oncotarget. 2015 Sep 15;6(27):24333-47.

7.

DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia.

Weiss CN, Ito K.

Int J Mol Sci. 2015 Mar 17;16(3):6183-201. doi: 10.3390/ijms16036183. Review.

8.

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers.

Tesauro C, Graziani G, Arnò B, Zuccaro L, Muzi A, D'Annessa I, Santori E, Tentori L, Leonetti C, Fiorani P, Desideri A.

J Exp Clin Cancer Res. 2014 Sep 17;33:71. doi: 10.1186/s13046-014-0071-z.

9.

Effect of nanostructured TiO₂ crystal phase on photoinduced apoptosis of breast cancer epithelial cells.

Lagopati N, Tsilibary EP, Falaras P, Papazafiri P, Pavlatou EA, Kotsopoulou E, Kitsiou P.

Int J Nanomedicine. 2014 Jul 3;9:3219-30. doi: 10.2147/IJN.S62972. eCollection 2014.

10.

Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.

Fischer JM, Popp O, Gebhard D, Veith S, Fischbach A, Beneke S, Leitenstorfer A, Bergemann J, Scheffner M, Ferrando-May E, Mangerich A, Bürkle A.

FEBS J. 2014 Aug;281(16):3625-41. doi: 10.1111/febs.12885. Epub 2014 Jul 21.

11.

The Sound of Silence: RNAi in Poly (ADP-Ribose) Research.

Blenn C, Wyrsch P, Althaus FR.

Genes (Basel). 2012 Dec 6;3(4):779-805. doi: 10.3390/genes3040779.

12.

Poly-ADP-ribose polymerase: machinery for nuclear processes.

Thomas C, Tulin AV.

Mol Aspects Med. 2013 Dec;34(6):1124-37. doi: 10.1016/j.mam.2013.04.001. Epub 2013 Apr 25. Review.

13.

Is there an epigenetic component underlying the resistance of triple-negative breast cancers to parp inhibitors?

Lovato A, Panasci L, Witcher M.

Front Pharmacol. 2012 Dec 27;3:202. doi: 10.3389/fphar.2012.00202. eCollection 2012.

14.

Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.

Popp O, Veith S, Fahrer J, Bohr VA, Bürkle A, Mangerich A.

ACS Chem Biol. 2013 Jan 18;8(1):179-88. doi: 10.1021/cb300363g. Epub 2012 Oct 29.

15.

Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.

King BS, Cooper KL, Liu KJ, Hudson LG.

J Biol Chem. 2012 Nov 16;287(47):39824-33. doi: 10.1074/jbc.M112.393504. Epub 2012 Oct 4.

16.

Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase.

Grady SL, Hwang J, Vastag L, Rabinowitz JD, Shenk T.

J Virol. 2012 Aug;86(15):8259-68. doi: 10.1128/JVI.00495-12. Epub 2012 May 23.

17.

Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli.

Boamah EK, Kotova E, Garabedian M, Jarnik M, Tulin AV.

PLoS Genet. 2012 Jan;8(1):e1002442. doi: 10.1371/journal.pgen.1002442. Epub 2012 Jan 5.

18.

Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins.

Gagné JP, Haince JF, Pic E, Poirier GG.

Methods Mol Biol. 2011;780:93-115. doi: 10.1007/978-1-61779-270-0_7.

19.

Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.

Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A, Grant R.

PLoS One. 2011 Apr 26;6(4):e19194. doi: 10.1371/journal.pone.0019194.

20.

p53 inhibits adeno-associated viral vector integration.

Zacharias J, Romanova LG, Menk J, Philpott NJ.

Hum Gene Ther. 2011 Nov;22(11):1445-51. doi: 10.1089/hum.2011.006. Epub 2011 Jun 8.

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