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Items: 1 to 20 of 43


Why are rods more sensitive than cones?

Ingram NT, Sampath AP, Fain GL.

J Physiol. 2016 Oct 1;594(19):5415-26. doi: 10.1113/JP272556.


Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.

Tayou J, Wang Q, Jang GF, Pronin AN, Orlandi C, Martemyanov KA, Crabb JW, Slepak VZ.

J Biol Chem. 2016 Apr 22;291(17):9133-47. doi: 10.1074/jbc.M115.694075.


Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.

Gerber KJ, Squires KE, Hepler JR.

Mol Pharmacol. 2016 Feb;89(2):273-86. doi: 10.1124/mol.115.102210. Review.


RGS Protein Regulation of Phototransduction.

Chen CK.

Prog Mol Biol Transl Sci. 2015;133:31-45. doi: 10.1016/bs.pmbts.2015.02.004. Review.


Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation.

Majumder A, Pahlberg J, Muradov H, Boyd KK, Sampath AP, Artemyev NO.

J Neurosci. 2015 Jun 17;35(24):9225-35. doi: 10.1523/JNEUROSCI.3563-14.2015.


The cone dysfunction syndromes.

Aboshiha J, Dubis AM, Carroll J, Hardcastle AJ, Michaelides M.

Br J Ophthalmol. 2016 Jan;100(1):115-21. doi: 10.1136/bjophthalmol-2014-306505. Review.


Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.

Tracy CM, Kolesnikov AV, Blake DR, Chen CK, Baehr W, Kefalov VJ, Willardson BM.

PLoS One. 2015 Feb 6;10(2):e0117129. doi: 10.1371/journal.pone.0117129.


R9AP targeting to rod outer segments is independent of rhodopsin and is guided by the SNARE homology domain.

Pearring JN, Lieu EC, Winter JR, Baker SA, Arshavsky VY.

Mol Biol Cell. 2014 Sep 1;25(17):2644-9. doi: 10.1091/mbc.E14-02-0747.


An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina.

Cain MD, Vo BQ, Kolesnikov AV, Kefalov VJ, Culican SM, Kerschensteiner D, Blumer KJ.

PLoS One. 2013 Dec 9;8(12):e82276. doi: 10.1371/journal.pone.0082276.


Quantitative aspects of cGMP phosphodiesterase activation in carp rods and cones.

Koshitani Y, Tachibanaki S, Kawamura S.

J Biol Chem. 2014 Jan 31;289(5):2651-7. doi: 10.1074/jbc.M113.495325.


Timing is everything: GTPase regulation in phototransduction.

Arshavsky VY, Wensel TG.

Invest Ophthalmol Vis Sci. 2013 Nov 21;54(12):7725-33. doi: 10.1167/iovs.13-13281. Review.


Light-induced translocation of RGS9-1 and Gβ5L in mouse rod photoreceptors.

Tian M, Zallocchi M, Wang W, Chen CK, Palczewski K, Delimont D, Cosgrove D, Peng YW.

PLoS One. 2013;8(3):e58832. doi: 10.1371/journal.pone.0058832.


Structural and functional analysis of the regulator of G protein signaling 2-gαq complex.

Nance MR, Kreutz B, Tesmer VM, Sterne-Marr R, Kozasa T, Tesmer JJ.

Structure. 2013 Mar 5;21(3):438-48. doi: 10.1016/j.str.2012.12.016.


Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

Mao W, Miyagishima KJ, Yao Y, Soreghan B, Sampath AP, Chen J.

J Biol Chem. 2013 Feb 22;288(8):5257-67. doi: 10.1074/jbc.M112.430058.


Low activation and fast inactivation of transducin in carp cones.

Tachibanaki S, Yonetsu S, Fukaya S, Koshitani Y, Kawamura S.

J Biol Chem. 2012 Nov 30;287(49):41186-94. doi: 10.1074/jbc.M112.403717.


RGS9 knockout causes a short delay in light responses of ON-bipolar cells.

Herrmann R, Lee B, Arshavsky VY.

PLoS One. 2011;6(11):e27573. doi: 10.1371/journal.pone.0027573.


Photoreceptor signaling: supporting vision across a wide range of light intensities.

Arshavsky VY, Burns ME.

J Biol Chem. 2012 Jan 13;287(3):1620-6. doi: 10.1074/jbc.R111.305243. Review.


Replacing the rod with the cone transducin subunit decreases sensitivity and accelerates response decay.

Chen CK, Woodruff ML, Chen FS, Shim H, Cilluffo MC, Fain GL.

J Physiol. 2010 Sep 1;588(Pt 17):3231-41. doi: 10.1113/jphysiol.2010.191221.


Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light.

Lobanova ES, Herrmann R, Finkelstein S, Reidel B, Skiba NP, Deng WT, Jo R, Weiss ER, Hauswirth WW, Arshavsky VY.

J Neurosci. 2010 May 19;30(20):6815-24. doi: 10.1523/JNEUROSCI.0613-10.2010.

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