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Items: 1 to 20 of 77


Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells.

Burchett KM, Etekpo A, Batra SK, Yan Y, Ouellette MM.

Oncotarget. 2017 Jul 20;8(48):83754-83767. doi: 10.18632/oncotarget.19410. eCollection 2017 Oct 13.


Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer.

Pedersen AK, Mendes Lopes de Melo J, Mørup N, Tritsaris K, Pedersen SF.

BMC Cancer. 2017 Aug 14;17(1):542. doi: 10.1186/s12885-017-3532-x.


Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway.

Ma L, Xu Y, Wei Z, Xin G, Xing Z, Niu H, Huang W.

Sci Rep. 2017 Aug 3;7(1):7197. doi: 10.1038/s41598-017-05416-8.


The anti-protozoan drug nifurtimox preferentially inhibits clonogenic tumor cells under hypoxic conditions.

Li Q, Lin Q, Kim H, Yun Z.

Am J Cancer Res. 2017 May 1;7(5):1084-1095. eCollection 2017.


Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin.

Joseph S, Yuen A, Singh V, Hmama Z.

Biol Open. 2017 Apr 15;6(4):481-488. doi: 10.1242/bio.023119.


Hypoxia-activated cytotoxicity of benznidazole against clonogenic tumor cells.

Li Q, Lin Q, Yun Z.

Cancer Biol Ther. 2016 Dec;17(12):1266-1273. doi: 10.1080/15384047.2016.1250988. Epub 2016 Oct 27.


Inhibition of the PI3K/AKT Pathway Sensitizes Oral Squamous Cell Carcinoma Cells to Anthracycline-Based Chemotherapy In Vitro.

Smolensky D, Rathore K, Bourn J, Cekanova M.

J Cell Biochem. 2017 Sep;118(9):2615-2624. doi: 10.1002/jcb.25747. Epub 2017 May 16.


Therapeutic evaluation of monoclonal antibody-maytansinoid conjugate as a model of RON-targeted drug delivery for pancreatic cancer treatment.

Yao HP, Feng L, Zhou JW, Zhang RW, Wang MH.

Am J Cancer Res. 2016 May 1;6(5):937-56. eCollection 2016.


Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells.

Yu X, Ai J, Cai L, Jing Y, Wang D, Dong J, Pascal LE, Zhang J, Luo R, Wang Z.

Oncotarget. 2016 May 17;7(20):29245-54. doi: 10.18632/oncotarget.8588.


Mitochondrial Targeted Antioxidant in Cerebral Ischemia.

Ahmed E, Donovan T, Yujiao L, Zhang Q.

J Neurol Neurosci. 2015;6(2). pii: 17.


The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.

Dine JL, O'Sullivan CC, Voeller D, Greer YE, Chavez KJ, Conway CM, Sinclair S, Stone B, Amiri-Kordestani L, Merchant AS, Hewitt SM, Steinberg SM, Swain SM, Lipkowitz S.

Breast Cancer Res Treat. 2016 Jan;155(2):235-51. doi: 10.1007/s10549-015-3673-z. Epub 2016 Jan 12.


Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy.

Foygel K, Sekar TV, Paulmurugan R.

PLoS One. 2015 Nov 4;10(11):e0141913. doi: 10.1371/journal.pone.0141913. eCollection 2015.


A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro.

Rathore K, Cekanova M.

Drug Des Devel Ther. 2015 Sep 25;9:5323-35. doi: 10.2147/DDDT.S90859. eCollection 2015.


LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells.

Maki Y, Fujimoto J, Lang W, Xu L, Behrens C, Wistuba II, Kadara H.

Sci Rep. 2015 Sep 7;5:13846. doi: 10.1038/srep13846.


TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas.

Seagle BL, Yang CP, Eng KH, Dandapani M, Odunsi-Akanji O, Goldberg GL, Odunsi K, Horwitz SB, Shahabi S.

Gynecol Oncol. 2015 Jul;138(1):159-64. doi: 10.1016/j.ygyno.2015.04.039. Epub 2015 May 6.


The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells.

Tong KL, Chan KL, AbuBakar S, Low BS, Ma HQ, Wong PF.

PLoS One. 2015 Mar 31;10(3):e0121752. doi: 10.1371/journal.pone.0121752. eCollection 2015.


Heat-modified citrus pectin induces apoptosis-like cell death and autophagy in HepG2 and A549 cancer cells.

Leclere L, Fransolet M, Cote F, Cambier P, Arnould T, Van Cutsem P, Michiels C.

PLoS One. 2015 Mar 20;10(3):e0115831. doi: 10.1371/journal.pone.0115831. eCollection 2015.


E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro.

Rahman S, Housein Z, Dabrowska A, Mayán MD, Boobis AR, Hajji N.

Environ Health Perspect. 2015 May;123(5):484-92. doi: 10.1289/ehp.1408302. Epub 2015 Jan 9.


A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli.

Smith CL, Matheson TD, Trombly DJ, Sun X, Campeau E, Han X, Yates JR 3rd, Kaufman PD.

Mol Biol Cell. 2014 Sep 15;25(18):2866-81. doi: 10.1091/mbc.E14-05-1029. Epub 2014 Jul 23.

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