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Items: 8


The Tec family kinase Itk exists as a folded monomer in vivo.

Qi Q, August A.

J Biol Chem. 2009 Oct 23;284(43):29882-92. doi: 10.1074/jbc.M109.003129. Epub 2009 Aug 28.


Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.

Schmidt U, van den Akker E, Parren-van Amelsvoort M, Litos G, de Bruijn M, Gutiérrez L, Hendriks RW, Ellmeier W, Löwenberg B, Beug H, von Lindern M.

J Exp Med. 2004 Mar 15;199(6):785-95. Epub 2004 Mar 8. Erratum in: J Exp Med. 2004 Apr 5;199(7):following 1031.


Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec.

Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A.

Mol Cell Biol. 2004 Mar;24(6):2455-66.


A specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cells.

Bony C, Roche S, Shuichi U, Sasaki T, Crackower MA, Penninger J, Mano H, Pucéat M.

J Cell Biol. 2001 Feb 19;152(4):717-28.


Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

Ellmeier W, Jung S, Sunshine MJ, Hatam F, Xu Y, Baltimore D, Mano H, Littman DR.

J Exp Med. 2000 Dec 4;192(11):1611-24.


RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation.

Rajagopal K, Sommers CL, Decker DC, Mitchell EO, Korthauer U, Sperling AI, Kozak CA, Love PE, Bluestone JA.

J Exp Med. 1999 Dec 6;190(11):1657-68.


Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.

Ohya K, Kajigaya S, Kitanaka A, Yoshida K, Miyazato A, Yamashita Y, Yamanaka T, Ikeda U, Shimada K, Ozawa K, Mano H.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11976-81.


STAT signaling in the pathogenesis and treatment of cancer.

Frank DA.

Mol Med. 1999 Jul;5(7):432-56. Review.

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