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Items: 17


Osteopontin -- a promising biomarker for cancer therapy.

Wei R, Wong JPC, Kwok HF.

J Cancer. 2017 Jul 15;8(12):2173-2183. doi: 10.7150/jca.20480. eCollection 2017. Review.


Activation of Protein Kinase G (PKG) Reduces Neointimal Hyperplasia, Inhibits Platelet Aggregation, and Facilitates Re-endothelialization.

Kim JY, Yang HM, Lee JE, Kim BK, Jin S, Lee J, Park KW, Cho HJ, Kwon YW, Lee HY, Kang HJ, Oh BH, Park YB, Kim HS.

Sci Rep. 2016 Nov 11;6:36979. doi: 10.1038/srep36979.


PPARĪ³ modulates vascular smooth muscle cell phenotype via a protein kinase G-dependent pathway and reduces neointimal hyperplasia after vascular injury.

Yang HM, Kim BK, Kim JY, Kwon YW, Jin S, Lee JE, Cho HJ, Lee HY, Kang HJ, Oh BH, Park YB, Kim HS.

Exp Mol Med. 2013 Nov 29;45:e65. doi: 10.1038/emm.2013.112.


A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension.

Schwappacher R, Kilic A, Kojonazarov B, Lang M, Diep T, Zhuang S, Gawlowski T, Schermuly RT, Pfeifer A, Boss GR, Pilz RB.

J Biol Chem. 2013 Jun 7;288(23):16557-66. doi: 10.1074/jbc.M113.458729. Epub 2013 Apr 23.


Thrombospondin-1 in early flow-related remodeling of mesenteric arteries from young normotensive and spontaneously hypertensive rats.

Lemkens P, Boari G, Fazzi G, Janssen G, Murphy-Ullrich J, Schiffers P, De Mey J.

Open Cardiovasc Med J. 2012;6:50-9. doi: 10.2174/1874192401206010050. Epub 2012 May 18.


Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation.

Zhao YD, Cai L, Mirza MK, Huang X, Geenen DL, Hofmann F, Yuan JX, Zhao YY.

Am J Pathol. 2012 Jun;180(6):2268-75. doi: 10.1016/j.ajpath.2012.02.016.


Possible involvement of Cyclic-GMP-dependent protein kinase on matrix metalloproteinase-2 expression in rat aortic smooth muscle cells.

Dey NB, Lincoln TM.

Mol Cell Biochem. 2012 Sep;368(1-2):27-35. doi: 10.1007/s11010-012-1339-2. Epub 2012 May 23.


Stabilization of cGMP-dependent protein kinase G (PKG) expression in vascular smooth muscle cells: contribution of 3'UTR of its mRNA.

Sellak H, Lincoln TM, Choi CS.

J Biochem. 2011 Apr;149(4):433-41. doi: 10.1093/jb/mvr003. Epub 2011 Feb 3.


cGMP-dependent protein kinase and the regulation of vascular smooth muscle cell gene expression: possible involvement of Elk-1 sumoylation.

Choi C, Sellak H, Brown FM, Lincoln TM.

Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1660-70. doi: 10.1152/ajpheart.00677.2010. Epub 2010 Aug 27.


Glucose downregulation of PKG-I protein mediates increased thrombospondin1-dependent TGF-{beta} activity in vascular smooth muscle cells.

Wang S, Lincoln TM, Murphy-Ullrich JE.

Am J Physiol Cell Physiol. 2010 May;298(5):C1188-97. doi: 10.1152/ajpcell.00330.2009. Epub 2010 Feb 17.


Stainless steel ions stimulate increased thrombospondin-1-dependent TGF-beta activation by vascular smooth muscle cells: implications for in-stent restenosis.

Pallero MA, Talbert Roden M, Chen YF, Anderson PG, Lemons J, Brott BC, Murphy-Ullrich JE.

J Vasc Res. 2010;47(4):309-22. doi: 10.1159/000265565. Epub 2009 Dec 16.


Emerging Roles of Natriuretic Peptides and their Receptors in Pathophysiology of Hypertension and Cardiovascular Regulation.

Pandey KN.

J Am Soc Hypertens. 2008 Jul-Aug;2(4):210-26. doi: 10.1016/j.jash.2008.02.001.


Modulation of pulmonary vascular smooth muscle cell phenotype in hypoxia: role of cGMP-dependent protein kinase and myocardin.

Zhou W, Negash S, Liu J, Raj JU.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L780-9. doi: 10.1152/ajplung.90295.2008. Epub 2009 Feb 27.


Calcium and cyclic nucleotides affect TNF-alpha-induced stem cell migration.

Kaplan E, Min JY, Ke Q, Chen Y, Niethammer M, Rana JS, Malek S, Verheugt FW, Morgan JP.

Biochem Biophys Res Commun. 2009 May 1;382(2):241-6. doi: 10.1016/j.bbrc.2009.02.068. Epub 2009 Feb 20.


Cyclic GMP specifically suppresses Type-Ialpha cGMP-dependent protein kinase expression by ubiquitination.

Dey NB, Busch JL, Francis SH, Corbin JD, Lincoln TM.

Cell Signal. 2009 Jun;21(6):859-66. doi: 10.1016/j.cellsig.2009.01.014. Epub 2009 Jan 8.


Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner.

Isenberg JS, Ridnour LA, Perruccio EM, Espey MG, Wink DA, Roberts DD.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13141-6. Epub 2005 Sep 6.

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