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Items: 1 to 20 of 195


A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.

Sdano MA, Fulcher JM, Palani S, Chandrasekharan MB, Parnell TJ, Whitby FG, Formosa T, Hill CP.

Elife. 2017 Aug 16;6. pii: e28723. doi: 10.7554/eLife.28723.


Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation.

Shetty A, Kallgren SP, Demel C, Maier KC, Spatt D, Alver BH, Cramer P, Park PJ, Winston F.

Mol Cell. 2017 Apr 6;66(1):77-88.e5. doi: 10.1016/j.molcel.2017.02.023. Epub 2017 Mar 30.


Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.

Malik I, Qiu C, Snavely T, Kaplan CD.

Nucleic Acids Res. 2017 May 5;45(8):4431-4451. doi: 10.1093/nar/gkx037.


A meiosis-specific Spt5 homolog involved in non-coding transcription.

Gruchota J, Denby Wilkes C, Arnaiz O, Sperling L, Nowak JK.

Nucleic Acids Res. 2017 May 5;45(8):4722-4732. doi: 10.1093/nar/gkw1318.


Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved?

Zhang Y, Najmi SM, Schneider DA.

Biochim Biophys Acta. 2017 Feb;1860(2):246-255. doi: 10.1016/j.bbagrm.2016.10.010. Epub 2016 Oct 27. Review.


Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.

Cui P, Jin H, Vutukuru MR, Kaplan CD.

G3 (Bethesda). 2016 Aug 9;6(8):2489-504. doi: 10.1534/g3.116.030346.


The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.

Zhang Y, French SL, Beyer AL, Schneider DA.

J Biol Chem. 2016 Feb 5;291(6):3010-8. doi: 10.1074/jbc.M115.673442. Epub 2015 Dec 9.


Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085. Epub 2015 Oct 8.


The Abundant Histone Chaperones Spt6 and FACT Collaborate to Assemble, Inspect, and Maintain Chromatin Structure in Saccharomyces cerevisiae.

McCullough L, Connell Z, Petersen C, Formosa T.

Genetics. 2015 Nov;201(3):1031-45. doi: 10.1534/genetics.115.180794. Epub 2015 Sep 28.


Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination.

Hwang JK, Alt FW, Yeap LS.

Microbiol Spectr. 2015 Feb;3(1):MDNA3-0037-2014. doi: 10.1128/microbiolspec.MDNA3-0037-2014. Review.


The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations.

Jeronimo C, Watanabe S, Kaplan CD, Peterson CL, Robert F.

Mol Cell. 2015 Jun 18;58(6):1113-23. doi: 10.1016/j.molcel.2015.03.030. Epub 2015 May 7.


Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I.

Engel KL, French SL, Viktorovskaya OV, Beyer AL, Schneider DA.

Mol Cell Biol. 2015 Jul;35(13):2321-31. doi: 10.1128/MCB.01499-14. Epub 2015 Apr 27.


Of social molecules: The interactive assembly of ASH1 mRNA-transport complexes in yeast.

Niedner A, Edelmann FT, Niessing D.

RNA Biol. 2014;11(8):998-1009. doi: 10.4161/rna.29946. Epub 2014 Oct 31. Review.


Histone deacetylases and phosphorylated polymerase II C-terminal domain recruit Spt6 for cotranscriptional histone reassembly.

Burugula BB, Jeronimo C, Pathak R, Jones JW, Robert F, Govind CK.

Mol Cell Biol. 2014 Nov 15;34(22):4115-29. doi: 10.1128/MCB.00695-14. Epub 2014 Sep 2.


RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.

Bowman EA, Kelly WG.

Nucleus. 2014 May-Jun;5(3):224-36. doi: 10.4161/nucl.29347. Epub 2014 May 30. Review.


The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis.

Dürr J, Lolas IB, Sørensen BB, Schubert V, Houben A, Melzer M, Deutzmann R, Grasser M, Grasser KD.

Nucleic Acids Res. 2014 Apr;42(7):4332-47. doi: 10.1093/nar/gku096. Epub 2014 Feb 4.


The role of Ctk1 kinase in termination of small non-coding RNAs.

Lenstra TL, Tudek A, Clauder S, Xu Z, Pachis ST, van Leenen D, Kemmeren P, Steinmetz LM, Libri D, Holstege FC.

PLoS One. 2013 Dec 4;8(12):e80495. doi: 10.1371/journal.pone.0080495. eCollection 2013.


A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation.

Dronamraju R, Strahl BD.

Nucleic Acids Res. 2014 Jan;42(2):870-81. doi: 10.1093/nar/gkt1003. Epub 2013 Oct 25.

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