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Items: 1 to 20 of 52


Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells.

DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN.

Biochem Pharmacol. 2018 Feb;148:155-162. doi: 10.1016/j.bcp.2017.12.022. Epub 2017 Dec 28.


Ca2+ ionophores are not suitable for inducing mPTP opening in murine isolated adult cardiac myocytes.

Panel M, Ghaleh B, Morin D.

Sci Rep. 2017 Jun 27;7(1):4283. doi: 10.1038/s41598-017-04618-4.


Lactated Ringer's solution for preventing myocardial reperfusion injury.

Koyama T.

Int J Cardiol Heart Vasc. 2017 Apr 7;15:1-8. doi: 10.1016/j.ijcha.2017.03.002. eCollection 2017 Jun.


Identifying Functional Cysteine Residues in the Mitochondria.

Bak DW, Pizzagalli MD, Weerapana E.

ACS Chem Biol. 2017 Apr 21;12(4):947-957. doi: 10.1021/acschembio.6b01074. Epub 2017 Feb 15.


Revisiting Mitochondrial pH with an Improved Algorithm for Calibration of the Ratiometric 5(6)-carboxy-SNARF-1 Probe Reveals Anticooperative Reaction with H+ Ions and Warrants Further Studies of Organellar pH.

Żurawik TM, Pomorski A, Belczyk-Ciesielska A, Goch G, Niedźwiedzka K, Kucharczyk R, Krężel A, Bal W.

PLoS One. 2016 Aug 24;11(8):e0161353. doi: 10.1371/journal.pone.0161353. eCollection 2016.


ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator.

Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Gooz MB, Lemasters JJ.

J Biol Chem. 2016 Sep 9;291(37):19642-50. doi: 10.1074/jbc.M116.734814. Epub 2016 Jul 25. Erratum in: J Biol Chem. 2017 Oct 13;292(41):16969.


Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis.

Weemhoff JL, Woolbright BL, Jenkins RE, McGill MR, Sharpe MR, Olson JC, Antoine DJ, Curry SC, Jaeschke H.

Liver Int. 2017 Mar;37(3):377-384. doi: 10.1111/liv.13202. Epub 2016 Aug 6.


Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline.

Hu J, Kholmukhamedov A, Lindsey CC, Beeson CC, Jaeschke H, Lemasters JJ.

Free Radic Biol Med. 2016 Aug;97:418-426. doi: 10.1016/j.freeradbiomed.2016.06.024. Epub 2016 Jun 23.


Mitochondrial Metabolism in Aging Heart.

Lesnefsky EJ, Chen Q, Hoppel CL.

Circ Res. 2016 May 13;118(10):1593-611. doi: 10.1161/CIRCRESAHA.116.307505. Review.


The role of glycine in regulated cell death.

Weinberg JM, Bienholz A, Venkatachalam MA.

Cell Mol Life Sci. 2016 Jun;73(11-12):2285-308. doi: 10.1007/s00018-016-2201-6. Epub 2016 Apr 11. Review.


Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.

Badr H, Kozai D, Sakaguchi R, Numata T, Mori Y.

Front Pharmacol. 2016 Feb 9;7:19. doi: 10.3389/fphar.2016.00019. eCollection 2016.


Mitochondrial Dysfunction and Autophagy in Hepatic Ischemia/Reperfusion Injury.

Go KL, Lee S, Zendejas I, Behrns KE, Kim JS.

Biomed Res Int. 2015;2015:183469. doi: 10.1155/2015/183469. Epub 2015 Dec 6. Review.


Role of Endothelial Cells in Myocardial Ischemia-Reperfusion Injury.

Singhal AK, Symons JD, Boudina S, Jaishy B, Shiu YT.

Vasc Dis Prev. 2010;7:1-14.


Microparticles mediate hepatic ischemia-reperfusion injury and are the targets of Diannexin (ASP8597).

Teoh NC, Ajamieh H, Wong HJ, Croft K, Mori T, Allison AC, Farrell GC.

PLoS One. 2014 Sep 15;9(9):e104376. doi: 10.1371/journal.pone.0104376. eCollection 2014.


Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers.

Kim JS, Wang JH, Biel TG, Kim DS, Flores-Toro JA, Vijayvargiya R, Zendejas I, Behrns KE.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):600-10. doi: 10.1016/j.taap.2013.10.006. Epub 2013 Oct 12.


Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter.

Schwartz J, Holmuhamedov E, Zhang X, Lovelace GL, Smith CD, Lemasters JJ.

Toxicol Appl Pharmacol. 2013 Nov 15;273(1):172-9. doi: 10.1016/j.taap.2013.08.027. Epub 2013 Sep 5.


The role of allopurinol's timing in the ischemia reperfusion injury of small intestine.

Sapalidis K, Papavramidis TS, Gialamas E, Deligiannidis N, Tzioufa V, Papavramidis S.

J Emerg Trauma Shock. 2013 Jul;6(3):203-8. doi: 10.4103/0974-2700.115346.


Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase.

Fang H, Liu A, Dahmen U, Dirsch O.

Cell Death Dis. 2013 Jun 27;4:e694. doi: 10.1038/cddis.2013.225.


Pathophysiology of acute kidney injury.

Basile DP, Anderson MD, Sutton TA.

Compr Physiol. 2012 Apr;2(2):1303-53. doi: 10.1002/cphy.c110041. Review.


Functions of autophagy in normal and diseased liver.

Czaja MJ, Ding WX, Donohue TM Jr, Friedman SL, Kim JS, Komatsu M, Lemasters JJ, Lemoine A, Lin JD, Ou JH, Perlmutter DH, Randall G, Ray RB, Tsung A, Yin XM.

Autophagy. 2013 Aug;9(8):1131-58. doi: 10.4161/auto.25063. Epub 2013 May 22. Review.

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