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Three novel mutations of STK11 gene in Chinese patients with Peutz-Jeghers syndrome.

Tan H, Mei L, Huang Y, Yang P, Li H, Peng Y, Chen C, Wei X, Pan Q, Liang D, Wu L.

BMC Med Genet. 2016 Nov 8;17(1):77.


Genetic Screening and Analysis of LKB1 Gene in Chinese Patients with Peutz-Jeghers Syndrome.

Chen C, Zhang X, Wang D, Wang F, Pan J, Wang Z, Liu C, Wu L, Lu H, Li N, Wei J, Shi H, Wan H, Zhu M, Chen S, Zhou Y, Zhou X, Yang L, Liu J.

Med Sci Monit. 2016 Oct 10;22:3628-3640.


Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3.

Shan T, Xiong Y, Zhang P, Li Z, Jiang Q, Bi P, Yue F, Yang G, Wang Y, Liu X, Kuang S.

Nat Commun. 2016 Jul 27;7:12205. doi: 10.1038/ncomms12205.


The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery.

Hahn MM, de Voer RM, Hoogerbrugge N, Ligtenberg MJ, Kuiper RP, van Kessel AG.

Cell Oncol (Dordr). 2016 Dec;39(6):491-510. Review.


Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients.

Yuan Y, Liu L, Chen H, Wang Y, Xu Y, Mao H, Li J, Mills GB, Shu Y, Li L, Liang H.

Cancer Cell. 2016 May 9;29(5):711-22. doi: 10.1016/j.ccell.2016.04.001.


Characterization of the STK11 splicing variant as a normal splicing isomer in a patient with Peutz-Jeghers syndrome harboring genomic deletion of the STK11 gene.

Masuda K, Kobayashi Y, Kimura T, Umene K, Misu K, Nomura H, Hirasawa A, Banno K, Kosaki K, Aoki D, Sugano K.

Hum Genome Var. 2016 Mar 3;3:16002. doi: 10.1038/hgv.2016.2.


Molecular Heterogeneity of Ewing Sarcoma as Detected by Ion Torrent Sequencing.

Zhang N, Liu H, Yue G, Zhang Y, You J, Wang H.

PLoS One. 2016 Apr 14;11(4):e0153546. doi: 10.1371/journal.pone.0153546. Erratum in: PLoS One. 2016 Oct 18;11(10 ):e0165251.


The Prognostic Value of Decreased LKB1 in Solid Tumors: A Meta-Analysis.

Xiao J, Zou Y, Chen X, Gao Y, Xie M, Lu X, Li W, He B, He S, You S, Chen Q.

PLoS One. 2016 Apr 1;11(4):e0152674. doi: 10.1371/journal.pone.0152674.


AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.

Lipovka Y, Konhilas JP.

Cardiovasc Pharm Open Access. 2015 Aug;4(3). pii: 154.


Molecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancer.

Tezcan G, Tunca B, Ak S, Cecener G, Egeli U.

World J Gastrointest Oncol. 2016 Jan 15;8(1):83-98. doi: 10.4251/wjgo.v8.i1.83. Review.


Energy disruptors: rising stars in anticancer therapy?

Bost F, Decoux-Poullot AG, Tanti JF, Clavel S.

Oncogenesis. 2016 Jan 18;5:e188. doi: 10.1038/oncsis.2015.46. Review.


Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.

Dasgupta B, Chhipa RR.

Trends Pharmacol Sci. 2016 Mar;37(3):192-206. doi: 10.1016/ Review.


Familial Gastric Cancers.

Setia N, Clark JW, Duda DG, Hong TS, Kwak EL, Mullen JT, Lauwers GY.

Oncologist. 2015 Dec;20(12):1365-77. doi: 10.1634/theoncologist.2015-0205. Review.


Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.

Avtanski DB, Nagalingam A, Bonner MY, Arbiser JL, Saxena NK, Sharma D.

Oncotarget. 2015 Oct 6;6(30):29947-62. doi: 10.18632/oncotarget.4937.


AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival.

Fisher KW, Das B, Kim HS, Clymer BK, Gehring D, Smith DR, Costanzo-Garvey DL, Fernandez MR, Brattain MG, Kelly DL, MacMillan J, White MA, Lewis RE.

Mol Cell Biol. 2015 Nov;35(22):3866-79. doi: 10.1128/MCB.00528-15.


Do hereditary syndrome-related gynecologic cancers have any specific features?

Neto N, Cunha TM.

Insights Imaging. 2015 Oct;6(5):545-52. doi: 10.1007/s13244-015-0425-x.


Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system.

Gailite I, Aerne BL, Tapon N.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5169-78. doi: 10.1073/pnas.1505512112.


Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?

Hardie DG.

Clin Cancer Res. 2015 Sep 1;21(17):3836-40. doi: 10.1158/1078-0432.CCR-14-3300. Review.


Endogenous Ligand for GPR120, Docosahexaenoic Acid, Exerts Benign Metabolic Effects on the Skeletal Muscles via AMP-activated Protein Kinase Pathway.

Kim N, Lee JO, Lee HJ, Kim HI, Kim JK, Lee YW, Lee SK, Kim SJ, Park SH, Kim HS.

J Biol Chem. 2015 Aug 14;290(33):20438-47. doi: 10.1074/jbc.M115.657379.


Lipopolysaccharides Promote S-Nitrosylation and Proteasomal Degradation of Liver Kinase B1 (LKB1) in Macrophages in Vivo.

Liu Z, Dai X, Zhu H, Zhang M, Zou MH.

J Biol Chem. 2015 Jul 31;290(31):19011-7. doi: 10.1074/jbc.M115.649210.

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