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Items: 1 to 20 of 28


Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.

Fedoriw AM, Menon D, Kim Y, Mu W, Magnuson T.

Development. 2015 Sep 1;142(17):2972-80. doi: 10.1242/dev.126078. Epub 2015 Jul 24.


DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia.

Weiss CN, Ito K.

Int J Mol Sci. 2015 Mar 17;16(3):6183-201. doi: 10.3390/ijms16036183. Review.


The DNA damage checkpoint protein RAD9A is essential for male meiosis in the mouse.

Vasileva A, Hopkins KM, Wang X, Weisbach MM, Friedman RA, Wolgemuth DJ, Lieberman HB.

J Cell Sci. 2013 Sep 1;126(Pt 17):3927-38. doi: 10.1242/jcs.126763. Epub 2013 Jun 20.


Roles of Chk1 in cell biology and cancer therapy.

Zhang Y, Hunter T.

Int J Cancer. 2014 Mar 1;134(5):1013-23. doi: 10.1002/ijc.28226. Epub 2013 May 28. Review.


Maintenance of imaginal disc plasticity and regenerative potential in Drosophila by p53.

Wells BS, Johnston LA.

Dev Biol. 2012 Jan 15;361(2):263-76. doi: 10.1016/j.ydbio.2011.10.012. Epub 2011 Oct 19.


Cul4A is essential for spermatogenesis and male fertility.

Kopanja D, Roy N, Stoyanova T, Hess RA, Bagchi S, Raychaudhuri P.

Dev Biol. 2011 Apr 15;352(2):278-87. doi: 10.1016/j.ydbio.2011.01.028. Epub 2011 Feb 1.


Chromatin remodeling finds its place in the DNA double-strand break response.

Pandita TK, Richardson C.

Nucleic Acids Res. 2009 Apr;37(5):1363-77. doi: 10.1093/nar/gkn1071. Epub 2009 Jan 12. Review.


Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer.

Lundgren K, Holm K, Nordenskjöld B, Borg A, Landberg G.

Breast Cancer Res. 2008;10(5):R81. doi: 10.1186/bcr2150. Epub 2008 Sep 29.


The cellular control of DNA double-strand breaks.

Scott SP, Pandita TK.

J Cell Biochem. 2006 Dec 15;99(6):1463-75. Review. Erratum in: J Cell Biochem. 2010 Dec 1;111(5):1375.


The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage.

Zhou J, Lim CU, Li JJ, Cai L, Zhang Y.

Cancer Lett. 2006 Nov 8;243(1):9-15. Epub 2006 Mar 10. Review.


Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable.

de Vries HI, Uyetake L, Lemstra W, Brunsting JF, Su TT, Kampinga HH, Sibon OC.

J Cell Sci. 2005 May 1;118(Pt 9):1833-42.


TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.

Perera D, Perez-Hidalgo L, Moens PB, Reini K, Lakin N, Syväoja JE, San-Segundo PA, Freire R.

Mol Biol Cell. 2004 Apr;15(4):1568-79. Epub 2004 Jan 12.


p53 down-regulates CHK1 through p21 and the retinoblastoma protein.

Gottifredi V, Karni-Schmidt O, Shieh SS, Prives C.

Mol Cell Biol. 2001 Feb;21(4):1066-76.


Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control.

Hang H, Rauth SJ, Hopkins KM, Lieberman HB.

Nucleic Acids Res. 2000 Nov 1;28(21):4340-9.


Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice.

Scherthan H, Jerratsch M, Dhar S, Wang YA, Goff SP, Pandita TK.

Mol Cell Biol. 2000 Oct;20(20):7773-83.


The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.

Shieh SY, Ahn J, Tamai K, Taya Y, Prives C.

Genes Dev. 2000 Feb 1;14(3):289-300. Erratum in: Genes Dev 2000 Mar 15;14(6):750.


Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53.

Chehab NH, Malikzay A, Appel M, Halazonetis TD.

Genes Dev. 2000 Feb 1;14(3):278-88.


Meiotic DNA replication checkpoint control in fission yeast.

Murakami H, Nurse P.

Genes Dev. 1999 Oct 1;13(19):2581-93.

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