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Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases.

de Souza JM, Goncalves BDC, Gomez MV, Vieira LB, Ribeiro FM.

Front Pharmacol. 2018 Feb 23;9:145. doi: 10.3389/fphar.2018.00145. eCollection 2018. Review.


miR-382 Contributes to Renal Tubulointerstitial Fibrosis by Downregulating HSPD1.

Fang Y, Xie T, Xue N, Kuang Q, Wei Z, Liang M, Ding X.

Oxid Med Cell Longev. 2017;2017:4708516. doi: 10.1155/2017/4708516. Epub 2017 Jun 7.


Plasma marker of tissue oxidative damage and edaravone as a scavenger drug against peroxyl radicals and peroxynitrite.

Yamamoto Y.

J Clin Biochem Nutr. 2017 Jan;60(1):49-54. doi: 10.3164/jcbn.16-63. Epub 2016 Nov 12. Review.


The Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP Synthase.

Kaludercic N, Giorgio V.

Oxid Med Cell Longev. 2016;2016:3869610. doi: 10.1155/2016/3869610. Epub 2016 Mar 10. Review.


Pathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP).

Islam BU, Habib S, Ahmad P, Allarakha S, Moinuddin, Ali A.

Indian J Clin Biochem. 2015 Oct;30(4):368-85. doi: 10.1007/s12291-014-0475-8. Epub 2015 Jan 20. Review.


DJ-1 knockout augments disease severity and shortens survival in a mouse model of ALS.

Lev N, Barhum Y, Lotan I, Steiner I, Offen D.

PLoS One. 2015 Mar 30;10(3):e0117190. doi: 10.1371/journal.pone.0117190. eCollection 2015.


Metal-deficient SOD1 in amyotrophic lateral sclerosis.

Hilton JB, White AR, Crouch PJ.

J Mol Med (Berl). 2015 May;93(5):481-7. doi: 10.1007/s00109-015-1273-3. Epub 2015 Mar 11. Review.


Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.

Liu KX, Edwards B, Lee S, Finelli MJ, Davies B, Davies KE, Oliver PL.

Brain. 2015 May;138(Pt 5):1167-81. doi: 10.1093/brain/awv039. Epub 2015 Mar 9.


Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients.

Abe K, Itoyama Y, Sobue G, Tsuji S, Aoki M, Doyu M, Hamada C, Kondo K, Yoneoka T, Akimoto M, Yoshino H; Edaravone ALS Study Group.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec;15(7-8):610-7. doi: 10.3109/21678421.2014.959024. Epub 2014 Oct 6.


Effects of resveratrol on hydrogen peroxide-induced oxidative stress in embryonic neural stem cells.

Konyalioglu S, Armagan G, Yalcin A, Atalayin C, Dagci T.

Neural Regen Res. 2013 Feb 25;8(6):485-95. doi: 10.3969/j.issn.1673-5374.2013.06.001.


Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord.

Yin HZ, Yu S, Hsu CI, Liu J, Acab A, Wu R, Tao A, Chiang BJ, Weiss JH.

Exp Neurol. 2014 Nov;261:1-9. doi: 10.1016/j.expneurol.2014.06.003. Epub 2014 Jun 8.


S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction.

Montagna C, Di Giacomo G, Rizza S, Cardaci S, Ferraro E, Grumati P, De Zio D, Maiani E, Muscoli C, Lauro F, Ilari S, Bernardini S, Cannata S, Gargioli C, Ciriolo MR, Cecconi F, Bonaldo P, Filomeni G.

Antioxid Redox Signal. 2014 Aug 1;21(4):570-87. doi: 10.1089/ars.2013.5696. Epub 2014 May 13.


Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis.

Tan W, Pasinelli P, Trotti D.

Biochim Biophys Acta. 2014 Aug;1842(8):1295-301. doi: 10.1016/j.bbadis.2014.02.009. Epub 2014 Feb 22. Review.


Antioxidant gene therapy against neuronal cell death.

Navarro-Yepes J, Zavala-Flores L, Anandhan A, Wang F, Skotak M, Chandra N, Li M, Pappa A, Martinez-Fong D, Del Razo LM, Quintanilla-Vega B, Franco R.

Pharmacol Ther. 2014 May;142(2):206-30. doi: 10.1016/j.pharmthera.2013.12.007. Epub 2013 Dec 12. Review.


Exploiting oxidative microenvironments in the body as triggers for drug delivery systems.

Joshi-Barr S, de Gracia Lux C, Mahmoud E, Almutairi A.

Antioxid Redox Signal. 2014 Aug 10;21(5):730-54. doi: 10.1089/ars.2013.5754. Epub 2014 Apr 15. Review.


Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1(G93A) mice.

Cai M, Choi SM, Song BK, Son I, Kim S, Yang EJ.

J Neuroinflammation. 2013 Oct 29;10:131. doi: 10.1186/1742-2094-10-131.


Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?

Muyderman H, Chen T.

Br J Pharmacol. 2014 Apr;171(8):2191-205. doi: 10.1111/bph.12476. Review.


SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration.

Milani P, Ambrosi G, Gammoh O, Blandini F, Cereda C.

Oxid Med Cell Longev. 2013;2013:836760. doi: 10.1155/2013/836760. Epub 2013 Jul 28. Review.


MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.

Lee JK, Shin JH, Hwang SG, Gwag BJ, McKee AC, Lee J, Kowall NW, Ryu H, Lim DS, Choi EJ.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12066-71. doi: 10.1073/pnas.1300894110. Epub 2013 Jul 1.

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