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Items: 1 to 20 of 498

1.

Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues.

Li QQ, Chen PG, Hu ZW, Cao Y, Chen LX, Chen YX, Zhao YF, Li YM.

Chem Sci. 2017 Nov 1;8(11):7675-7681. doi: 10.1039/c7sc03217j. Epub 2017 Sep 12.

2.

p53 isoforms regulate premature aging in human cells.

von Muhlinen N, Horikawa I, Alam F, Isogaya K, Lissa D, Vojtesek B, Lane DP, Harris CC.

Oncogene. 2018 May;37(18):2379-2393. doi: 10.1038/s41388-017-0101-3. Epub 2018 Feb 12.

PMID:
29429991
3.

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.

Madan E, Parker TM, Bauer MR, Dhiman A, Pelham CJ, Nagane M, Kuppusamy ML, Holmes M, Holmes TR, Shaik K, Shee K, Kiparoidze S, Smith SD, Park YA, Gomm JJ, Jones LJ, Tomás AR, Cunha AC, Selvendiran K, Hansen LA, Fersht AR, Hideg K, Gogna R, Kuppusamy P.

J Biol Chem. 2018 Mar 23;293(12):4262-4276. doi: 10.1074/jbc.RA117.000950. Epub 2018 Jan 30.

PMID:
29382728
4.

Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic.

Al-Eryani L, Waigel S, Tyagi A, Peremarti J, Jenkins SF, Damodaran C, States JC.

Toxicol Sci. 2018 Apr 1;162(2):645-654. doi: 10.1093/toxsci/kfx292.

PMID:
29319823
5.

Protective Effect of Unacylated Ghrelin on Compression-Induced Skeletal Muscle Injury Mediated by SIRT1-Signaling.

Ugwu FN, Yu AP, Sin TK, Tam BT, Lai CW, Wong SC, Siu PM.

Front Physiol. 2017 Nov 24;8:962. doi: 10.3389/fphys.2017.00962. eCollection 2017.

6.

Betanodavirus B2 protein triggers apoptosis and necroptosis in lung cancer cells that suppresses autophagy.

Chiu HW, Su YC, Hong JR.

Oncotarget. 2017 Oct 6;8(55):94129-94141. doi: 10.18632/oncotarget.21588. eCollection 2017 Nov 7.

7.

Orellanine specifically targets renal clear cell carcinoma.

Buvall L, Hedman H, Khramova A, Najar D, Bergwall L, Ebefors K, Sihlbom C, Lundstam S, Herrmann A, Wallentin H, Roos E, Nilsson UA, Johansson M, Törnell J, Haraldsson B, Nyström J.

Oncotarget. 2017 Jul 25;8(53):91085-91098. doi: 10.18632/oncotarget.19555. eCollection 2017 Oct 31.

8.

Relevance of the p53-MDM2 axis to aging.

Wu D, Prives C.

Cell Death Differ. 2018 Jan;25(1):169-179. doi: 10.1038/cdd.2017.187. Epub 2017 Dec 1. Review.

PMID:
29192902
9.

Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells.

Panagaki T, Michael M, Hölscher C.

Sci Rep. 2017 Nov 23;7(1):16158. doi: 10.1038/s41598-017-16488-x.

10.

How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?

Aubrey BJ, Kelly GL, Janic A, Herold MJ, Strasser A.

Cell Death Differ. 2018 Jan;25(1):104-113. doi: 10.1038/cdd.2017.169. Epub 2017 Nov 17. Review.

PMID:
29149101
11.

Bardoxolone methyl (CDDO-Me or RTA402) induces cell cycle arrest, apoptosis and autophagy via PI3K/Akt/mTOR and p38 MAPK/Erk1/2 signaling pathways in K562 cells.

Wang XY, Zhang XH, Peng L, Liu Z, Yang YX, He ZX, Dang HW, Zhou SF.

Am J Transl Res. 2017 Oct 15;9(10):4652-4672. eCollection 2017.

12.

The Role of MDM2 in Promoting Genome Stability versus Instability.

Saadatzadeh MR, Elmi AN, Pandya PH, Bijangi-Vishehsaraei K, Ding J, Stamatkin CW, Cohen-Gadol AA, Pollok KE.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2216. doi: 10.3390/ijms18102216. Review.

13.

Inhibitory effect of black tea pigments, theaflavin‑3/3'-gallate against cisplatin-resistant ovarian cancer cells by inducing apoptosis and G1 cell cycle arrest.

Pan H, Wang F, Rankin GO, Rojanasakul Y, Tu Y, Chen YC.

Int J Oncol. 2017 Nov;51(5):1508-1520. doi: 10.3892/ijo.2017.4145. Epub 2017 Oct 3.

14.

Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cells.

Devhare P, Meyer K, Steele R, Ray RB, Ray R.

Cell Death Dis. 2017 Oct 12;8(10):e3106. doi: 10.1038/cddis.2017.517.

15.

Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53-Dependent Apoptosis.

Qiu XX, Liu Y, Zhang YF, Guan YN, Jia QQ, Wang C, Liang H, Li YQ, Yang HT, Qin YW, Huang S, Zhao XX, Jing Q.

J Am Heart Assoc. 2017 Oct 2;6(10). pii: e005295. doi: 10.1161/JAHA.116.005295.

16.

The IGF-1R/AKT pathway determines cell fate in response to p53.

Duan L, Maki CG.

Transl Cancer Res. 2016 Dec;5(6):664-675. doi: 10.21037/tcr.2016.09.16.

17.

Regulation of cytotoxic T-cell responses by p53 in cancer.

Braun MW, Iwakuma T.

Transl Cancer Res. 2016 Dec;5(6):692-697. doi: 10.21037/tcr.2016.11.76.

18.

SOX14 activates the p53 signaling pathway and induces apoptosis in a cervical carcinoma cell line.

Stanisavljevic D, Petrovic I, Vukovic V, Schwirtlich M, Gredic M, Stevanovic M, Popovic J.

PLoS One. 2017 Sep 19;12(9):e0184686. doi: 10.1371/journal.pone.0184686. eCollection 2017.

19.

Putting p53 in Context.

Kastenhuber ER, Lowe SW.

Cell. 2017 Sep 7;170(6):1062-1078. doi: 10.1016/j.cell.2017.08.028. Review.

PMID:
28886379
20.

Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53.

Seo JY, Kim DY, Kim SH, Kim HJ, Ryu HG, Lee J, Lee KH, Kim KT.

Oncotarget. 2017 Apr 10;8(31):51108-51122. doi: 10.18632/oncotarget.17003. eCollection 2017 Aug 1.

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