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Items: 11


Compartmentalized gene expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form.

Boggavarapu NR, Lalitkumar S, Joshua V, Kasvandik S, Salumets A, Lalitkumar PG, Gemzell-Danielsson K.

Sci Rep. 2016 Sep 26;6:33811. doi: 10.1038/srep33811.


Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells.

Shayhidin EE, Forcellini E, Boulanger MC, Mahmut A, Dautrey S, Barbeau X, Lagüe P, Sévigny J, Paquin JF, Mathieu P.

Br J Pharmacol. 2015 Aug;172(16):4189-99. doi: 10.1111/bph.13204. Epub 2015 Jul 8.


Ticlopidine in its prodrug form is a selective inhibitor of human NTPDase1.

Lecka J, Fausther M, Künzli B, Sévigny J.

Mediators Inflamm. 2014;2014:547480. doi: 10.1155/2014/547480. Epub 2014 Aug 11.


Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold.

Nadel Y, Lecka J, Gilad Y, Ben-David G, Förster D, Reiser G, Kenigsberg S, Camden J, Weisman GA, Senderowitz H, Sévigny J, Fischer B.

J Med Chem. 2014 Jun 12;57(11):4677-91. doi: 10.1021/jm500196c. Epub 2014 May 30.


8-BuS-ATP derivatives as specific NTPDase1 inhibitors.

Lecka J, Gillerman I, Fausther M, Salem M, Munkonda MN, Brosseau JP, Cadot C, Martín-Satué M, d'Orléans-Juste P, Rousseau E, Poirier D, Künzli B, Fischer B, Sévigny J.

Br J Pharmacol. 2013 May;169(1):179-96. doi: 10.1111/bph.12135.


Cellular function and molecular structure of ecto-nucleotidases.

Zimmermann H, Zebisch M, Sträter N.

Purinergic Signal. 2012 Sep;8(3):437-502. doi: 10.1007/s11302-012-9309-4. Epub 2012 May 4. Review.


Identification of hydrolytically stable and selective P2Y(1) receptor agonists.

Eliahu SE, Camden J, Lecka J, Weisman GA, Sévigny J, Gélinas S, Fischer B.

Eur J Med Chem. 2009 Apr;44(4):1525-36. doi: 10.1016/j.ejmech.2008.07.015. Epub 2008 Jul 22.


Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases.

Lévesque SA, Lavoie EG, Lecka J, Bigonnesse F, Sévigny J.

Br J Pharmacol. 2007 Sep;152(1):141-50. Epub 2007 Jul 2.


International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy.

Abbracchio MP, Burnstock G, Boeynaems JM, Barnard EA, Boyer JL, Kennedy C, Knight GE, Fumagalli M, Gachet C, Jacobson KA, Weisman GA.

Pharmacol Rev. 2006 Sep;58(3):281-341. Review.


Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis.

Bello V, Goding JW, Greengrass V, Sali A, Dubljevic V, Lenoir C, Trugnan G, Maurice M.

Mol Biol Cell. 2001 Oct;12(10):3004-15.

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