Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 49

1.

Hepatitis C virus induces a prediabetic state by directly impairing hepatic glucose metabolism in mice.

Lerat H, Imache MR, Polyte J, Gaudin A, Mercey M, Donati F, Baudesson C, Higgs MR, Picard A, Magnan C, Foufelle F, Pawlotsky JM.

J Biol Chem. 2017 Aug 4;292(31):12860-12873. doi: 10.1074/jbc.M117.785030. Epub 2017 May 30.

PMID:
28559285
2.

CAMK2γ antagonizes mTORC1 activation during hepatocarcinogenesis.

Meng Z, Ma X, Du J, Wang X, He M, Gu Y, Zhang J, Han W, Fang Z, Gan X, Van Ness C, Fu X, Schones DE, Xu R, Huang W.

Oncogene. 2017 Apr 27;36(17):2446-2456. doi: 10.1038/onc.2016.400. Epub 2016 Nov 7.

PMID:
27819676
3.

Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.

Najem D, Bamji-Mirza M, Yang Z, Zhang W.

Neurosci Bull. 2016 Jun;32(3):227-38. doi: 10.1007/s12264-016-0034-9. Epub 2016 May 20.

4.

Nutrient Excess in AMPK Downregulation and Insulin Resistance.

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK.

J Endocrinol Diabetes Obes. 2013 Jul-Sep;1(1):1008.

5.

Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism.

Wicks SE, Vandanmagsar B, Haynie KR, Fuller SE, Warfel JD, Stephens JM, Wang M, Han X, Zhang J, Noland RC, Mynatt RL.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3300-9. doi: 10.1073/pnas.1418560112. Epub 2015 Jun 8.

6.

Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.

Ando Y, Shinozawa Y, Iijima Y, Yu BC, Sone M, Ooi Y, Watanaka Y, Chida K, Hakuno F, Takahashi S.

J Biol Chem. 2015 Feb 27;290(9):5881-92. doi: 10.1074/jbc.M114.624759. Epub 2015 Jan 13.

7.

Inhibited insulin signaling in mouse hepatocytes is associated with increased phosphatidic acid but not diacylglycerol.

Zhang C, Hwarng G, Cooper DE, Grevengoed TJ, Eaton JM, Natarajan V, Harris TE, Coleman RA.

J Biol Chem. 2015 Feb 6;290(6):3519-28. doi: 10.1074/jbc.M114.602789. Epub 2014 Dec 15.

8.

Insulin resistance and muscle insulin receptor substrate-1 serine hyperphosphorylation.

Stuart CA, Howell ME, Cartwright BM, McCurry MP, Lee ML, Ramsey MW, Stone MH.

Physiol Rep. 2014 Dec 3;2(12). pii: e12236. doi: 10.14814/phy2.12236. Print 2014 Dec 1.

9.

Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.

Hançer NJ, Qiu W, Cherella C, Li Y, Copps KD, White MF.

J Biol Chem. 2014 May 2;289(18):12467-84. doi: 10.1074/jbc.M114.554162. Epub 2014 Mar 20.

10.

Insulin receptor signaling in normal and insulin-resistant states.

Boucher J, Kleinridders A, Kahn CR.

Cold Spring Harb Perspect Biol. 2014 Jan 1;6(1). pii: a009191. doi: 10.1101/cshperspect.a009191. Review.

11.

Exercise reduces cellular stress related to skeletal muscle insulin resistance.

de Matos MA, Ottone Vde O, Duarte TC, Sampaio PF, Costa KB, Fonseca CA, Neves MP, Schneider SM, Moseley P, Coimbra CC, Magalhães Fde C, Rocha-Vieira E, Amorim FT.

Cell Stress Chaperones. 2014 Mar;19(2):263-70. doi: 10.1007/s12192-013-0453-8. Epub 2013 Aug 22.

12.

Burn injury-induced IRS-1 degradation in mouse skeletal muscle.

Lu XM, Tompkins R, Fischman A.

Int J Burns Trauma. 2013;3(1):37-48. Epub 2013 Jan 24.

13.

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2.

Copps KD, White MF.

Diabetologia. 2012 Oct;55(10):2565-2582. doi: 10.1007/s00125-012-2644-8. Epub 2012 Aug 8. Review.

14.

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.

Zhang C, Wendel AA, Keogh MR, Harris TE, Chen J, Coleman RA.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1667-72. doi: 10.1073/pnas.1110730109. Epub 2012 Jan 17.

15.

Inhibition of insulin signaling in endothelial cells by protein kinase C-induced phosphorylation of p85 subunit of phosphatidylinositol 3-kinase (PI3K).

Maeno Y, Li Q, Park K, Rask-Madsen C, Gao B, Matsumoto M, Liu Y, Wu IH, White MF, Feener EP, King GL.

J Biol Chem. 2012 Feb 10;287(7):4518-30. doi: 10.1074/jbc.M111.286591. Epub 2011 Dec 12.

16.

Why do anti-inflammatory therapies fail to improve insulin sensitivity?

Gao ZG, Ye JP.

Acta Pharmacol Sin. 2012 Feb;33(2):182-8. doi: 10.1038/aps.2011.131. Epub 2011 Oct 31. Review.

17.

α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.

Tiwary R, Yu W, Sanders BG, Kline K.

Br J Cancer. 2011 Jan 4;104(1):101-9. doi: 10.1038/sj.bjc.6606019. Epub 2010 Nov 30.

18.

Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice.

Mavalli MD, DiGirolamo DJ, Fan Y, Riddle RC, Campbell KS, van Groen T, Frank SJ, Sperling MA, Esser KA, Bamman MM, Clemens TL.

J Clin Invest. 2010 Nov;120(11):4007-20. doi: 10.1172/JCI42447.

19.

Molecular mechanism of insulin resistance in obesity and type 2 diabetes.

Choi K, Kim YB.

Korean J Intern Med. 2010 Jun;25(2):119-29. doi: 10.3904/kjim.2010.25.2.119. Epub 2010 Jun 1. Review.

20.

Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats.

Zheng Y, Zhang W, Pendleton E, Leng S, Wu J, Chen R, Sun XJ.

J Endocrinol. 2009 Dec;203(3):337-47. doi: 10.1677/JOE-09-0181. Epub 2009 Oct 2.

Supplemental Content

Support Center