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Items: 14


The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias.

Andersson AK, Ma J, Wang J, Chen X, Gedman AL, Dang J, Nakitandwe J, Holmfeldt L, Parker M, Easton J, Huether R, Kriwacki R, Rusch M, Wu G, Li Y, Mulder H, Raimondi S, Pounds S, Kang G, Shi L, Becksfort J, Gupta P, Payne-Turner D, Vadodaria B, Boggs K, Yergeau D, Manne J, Song G, Edmonson M, Nagahawatte P, Wei L, Cheng C, Pei D, Sutton R, Venn NC, Chetcuti A, Rush A, Catchpoole D, Heldrup J, Fioretos T, Lu C, Ding L, Pui CH, Shurtleff S, Mullighan CG, Mardis ER, Wilson RK, Gruber TA, Zhang J, Downing JR; St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project..

Nat Genet. 2015 Apr;47(4):330-7. doi: 10.1038/ng.3230. Epub 2015 Mar 2.


Acute lymphoblastic leukemia with mature B-cell phenotype and t(9;11;11)(p22;q23;p11.2): a case study and literature review.

Kim B, Lee ST, Kim HJ, Lee SH, Yoo KH, Koo HH, Kim SH.

Ann Lab Med. 2014 Mar;34(2):166-9. doi: 10.3343/alm.2014.34.2.166. Epub 2014 Feb 13. Review. No abstract available.


The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.

Glukhov SI, Rubtsov MA, Alexeyevsky DA, Alexeevski AV, Razin SV, Iarovaia OV.

PLoS One. 2013 Sep 25;8(9):e75871. doi: 10.1371/journal.pone.0075871. eCollection 2013.


Recombination and its roles in DNA repair, cellular immortalization and cancer.

Shammas MA, Shmookler Reis RJ.

Age (Omaha). 1999 Apr;22(2):71-88. doi: 10.1007/s11357-999-0009-0.


Roles of retrotransposons in benign and malignant hematologic disease.

Schneider AM, Duffield AS, Symer DE, Burns KH.

Cellscience. 2009 Oct 27;6(2):121-145.


Chromosomal translocations involving the MLL gene: molecular mechanisms.

Aplan PD.

DNA Repair (Amst). 2006 Sep 8;5(9-10):1265-72. Epub 2006 Jun 21. Review.


Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination.

Woodward KJ, Cundall M, Sperle K, Sistermans EA, Ross M, Howell G, Gribble SM, Burford DC, Carter NP, Hobson DL, Garbern JY, Kamholz J, Heng H, Hodes ME, Malcolm S, Hobson GM.

Am J Hum Genet. 2005 Dec;77(6):966-87. Epub 2005 Oct 19.


Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17.

Kehrer-Sawatzki H, Schreiner B, Tänzer S, Platzer M, Müller S, Hameister H.

Am J Hum Genet. 2002 Aug;71(2):375-88. Epub 2002 Jul 1.


A novel selection system for chromosome translocations in Saccharomyces cerevisiae.

Tennyson RB, Ebran N, Herrera AE, Lindsley JE.

Genetics. 2002 Apr;160(4):1363-73.


Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.

Raffini LJ, Slater DJ, Rappaport EF, Lo Nigro L, Cheung NK, Biegel JA, Nowell PC, Lange BJ, Felix CA.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4568-73.


Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3070-5. Epub 2002 Feb 26.


Molecular emergence of acute myeloid leukemia during treatment for acute lymphoblastic leukemia.

Blanco JG, Dervieux T, Edick MJ, Mehta PK, Rubnitz JE, Shurtleff S, Raimondi SC, Behm FG, Pui CH, Relling MV.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10338-43.


Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia.

Kourlas PJ, Strout MP, Becknell B, Veronese ML, Croce CM, Theil KS, Krahe R, Ruutu T, Knuutila S, Bloomfield CD, Caligiuri MA.

Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2145-50.


The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.

Touchman JW, Anikster Y, Dietrich NL, Maduro VV, McDowell G, Shotelersuk V, Bouffard GG, Beckstrom-Sternberg SM, Gahl WA, Green ED.

Genome Res. 2000 Feb;10(2):165-73.

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