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Items: 1 to 20 of 35

1.

Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.

Rodgers SJ, Ferguson DT, Mitchell CA, Ooms LM.

Biosci Rep. 2017 Feb 10;37(1). pii: BSR20160432. doi: 10.1042/BSR20160432. Print 2017 Feb 28. Review.

2.

Phosphatidylinositolphosphate phosphatase activities and cancer.

Rudge SA, Wakelam MJ.

J Lipid Res. 2016 Feb;57(2):176-92. doi: 10.1194/jlr.R059154. Epub 2015 Aug 24. Review.

3.

PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.

Thorpe LM, Yuzugullu H, Zhao JJ.

Nat Rev Cancer. 2015 Jan;15(1):7-24. doi: 10.1038/nrc3860. Review.

4.

Phosphoinositides: Key modulators of energy metabolism.

Bridges D, Saltiel AR.

Biochim Biophys Acta. 2015 Jun;1851(6):857-66. doi: 10.1016/j.bbalip.2014.11.008. Epub 2014 Nov 20. Review.

5.

SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.

Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A.

Mol Cell. 2014 Nov 20;56(4):595-607. doi: 10.1016/j.molcel.2014.09.023. Epub 2014 Oct 30.

6.

Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation.

Egami Y, Taguchi T, Maekawa M, Arai H, Araki N.

Front Physiol. 2014 Sep 30;5:374. doi: 10.3389/fphys.2014.00374. eCollection 2014. Review.

7.

The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.

Hsu F, Mao Y.

Biochim Biophys Acta. 2015 Jun;1851(6):698-710. doi: 10.1016/j.bbalip.2014.09.015. Epub 2014 Sep 28. Review.

8.

Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy.

Chen M, Nowak DG, Trotman LC.

Clin Cancer Res. 2014 Jun 15;20(12):3057-63. doi: 10.1158/1078-0432.CCR-12-3680.

9.

Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.

Maekawa M, Terasaka S, Mochizuki Y, Kawai K, Ikeda Y, Araki N, Skolnik EY, Taguchi T, Arai H.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E978-87. doi: 10.1073/pnas.1311029111. Epub 2014 Mar 3.

10.

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC.

Cell. 2013 Nov 7;155(4):844-57. doi: 10.1016/j.cell.2013.09.057.

11.

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.

Devereaux K, Dall'Armi C, Alcazar-Roman A, Ogasawara Y, Zhou X, Wang F, Yamamoto A, De Camilli P, Di Paolo G.

PLoS One. 2013 Oct 3;8(10):e76405. doi: 10.1371/journal.pone.0076405. eCollection 2013.

12.

Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.

13.

Biochemistry and structure of phosphoinositide phosphatases.

Kim YJ, Jahan N, Bahk YY.

BMB Rep. 2013 Jan;46(1):1-8. Review.

14.

Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas.

Balakrishnan A, Chaillet JR.

Dev Biol. 2013 Jan 1;373(1):118-29. doi: 10.1016/j.ydbio.2012.10.011. Epub 2012 Oct 16.

15.

Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells.

Kim JS, Yun HS, Um HD, Park JK, Lee KH, Kang CM, Lee SJ, Hwang SG.

Cancer Biol Ther. 2012 Nov;13(13):1307-18. doi: 10.4161/cbt.21788. Epub 2012 Aug 16.

16.

Phosphatases: the new brakes for cancer development?

Zhang Q, Claret FX.

Enzyme Res. 2012;2012:659649. doi: 10.1155/2012/659649. Epub 2011 Oct 31.

17.

Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans.

Ferron M, Boudiffa M, Arsenault M, Rached M, Pata M, Giroux S, Elfassihi L, Kisseleva M, Majerus PW, Rousseau F, Vacher J.

Cell Metab. 2011 Oct 5;14(4):466-77. doi: 10.1016/j.cmet.2011.08.013.

18.

INPP4B: the new kid on the PI3K block.

Agoulnik IU, Hodgson MC, Bowden WA, Ittmann MM.

Oncotarget. 2011 Apr;2(4):321-8. Review.

19.

Wandering through the laboratory.

Majerus PW.

J Biol Chem. 2011 Feb 18;286(7):4941-5. doi: 10.1074/jbc.X110.212894. Epub 2010 Dec 17. No abstract available.

20.

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers.

Fedele CG, Ooms LM, Ho M, Vieusseux J, O'Toole SA, Millar EK, Lopez-Knowles E, Sriratana A, Gurung R, Baglietto L, Giles GG, Bailey CG, Rasko JE, Shields BJ, Price JT, Majerus PW, Sutherland RL, Tiganis T, McLean CA, Mitchell CA.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22231-6. doi: 10.1073/pnas.1015245107. Epub 2010 Dec 2.

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