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Items: 1 to 20 of 288

1.

Prospects for the Use of ATR Inhibitors to Treat Cancer.

Wagner JM, Kaufmann SH.

Pharmaceuticals (Basel). 2010 Apr 28;3(5):1311-1334. Review.

PMID:
27713304
2.

Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword.

Visconti R, Della Monica R, Grieco D.

J Exp Clin Cancer Res. 2016 Sep 27;35(1):153. Review.

PMID:
27670139
3.

Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer.

Yang SH, Kuo TC, Wu H, Guo JC, Hsu C, Hsu CH, Tien YW, Yeh KH, Cheng AL, Kuo SH.

World J Gastroenterol. 2016 Aug 28;22(32):7275-88. doi: 10.3748/wjg.v22.i32.7275. Review.

PMID:
27621574
4.

Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle.

Chiu HC, Huang WR, Liao TL, Wu HY, Munir M, Shih WL, Liu HJ.

PLoS One. 2016 Sep 7;11(9):e0162356. doi: 10.1371/journal.pone.0162356.

PMID:
27603133
5.

Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1.

de Boer HR, Llobet SG, van Vugt MA.

Cell Mol Life Sci. 2016 Aug;73(15):2985-2998. No abstract available.

PMID:
27251328
6.

Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization tool.

Doyle F, Leonardi A, Endres L, Tenenbaum SA, Dedon PC, Begley TJ.

Methods. 2016 Sep 1;107:98-109. doi: 10.1016/j.ymeth.2016.05.010.

PMID:
27245397
7.

The role of VDR and BIM in potentiation of cytarabine-induced cell death in human AML blasts.

Harrison JS, Wang X, Studzinski GP.

Oncotarget. 2016 Jun 14;7(24):36447-36460. doi: 10.18632/oncotarget.8998.

PMID:
27144333
8.

Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics.

Petrone A, Adamo ME, Cheng C, Kettenbach AN.

Mol Cell Proteomics. 2016 Jul;15(7):2448-61. doi: 10.1074/mcp.M116.059394.

PMID:
27134283
9.

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.

Ruiz S, Mayor-Ruiz C, Lafarga V, Murga M, Vega-Sendino M, Ortega S, Fernandez-Capetillo O.

Mol Cell. 2016 Apr 21;62(2):307-13. doi: 10.1016/j.molcel.2016.03.006.

PMID:
27067599
10.

Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.

Lopez SM, Agoulnik AI, Zhang M, Peterson LE, Suarez E, Gandarillas GA, Frolov A, Li R, Rajapakshe K, Coarfa C, Ittmann MM, Weigel NL, Agoulnik IU.

Clin Cancer Res. 2016 Aug 1;22(15):3937-49. doi: 10.1158/1078-0432.CCR-15-1983.

PMID:
26968201
11.

New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress.

Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, Agell N.

Nucleic Acids Res. 2016 Jun 2;44(10):4745-62. doi: 10.1093/nar/gkw132.

PMID:
26939887
12.

The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells.

Liberio MS, Sadowski MC, Davis RA, Rockstroh A, Vasireddy R, Lehman ML, Nelson CC.

Oncotarget. 2015 Dec 22;6(41):43944-63. doi: 10.18632/oncotarget.6267.

PMID:
26733491
13.

A Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage Response.

Lin X, Ojo D, Wei F, Wong N, Gu Y, Tang D.

Biomolecules. 2015 Dec 1;5(4):3396-415. doi: 10.3390/biom5043396. Review.

PMID:
26633535
14.

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

Heijink AM, Blomen VA, Bisteau X, Degener F, Matsushita FY, Kaldis P, Foijer F, van Vugt MA.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15160-5. doi: 10.1073/pnas.1505283112.

PMID:
26598692
15.

Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo.

Qi W, Zhang W, Edwards H, Chu R, Madlambayan GJ, Taub JW, Wang Z, Wang Y, Li C, Lin H, Ge Y.

Cancer Biol Ther. 2015;16(12):1784-93. doi: 10.1080/15384047.2015.1095406.

PMID:
26529495
16.

MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.

Estrada-Bernal A, Chatterjee M, Haque SJ, Yang L, Morgan MA, Kotian S, Morrell D, Chakravarti A, Williams TM.

Cell Cycle. 2015;14(23):3713-24. doi: 10.1080/15384101.2015.1104437.

PMID:
26505547
17.

Evelyn Witkin and Stephen Elledge share the 2015 Lasker Basic Medical Award.

Jackson S.

J Clin Invest. 2015 Oct 1;125(10):3727-31. doi: 10.1172/JCI84318. No abstract available.

PMID:
26345423
18.

DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.

Slaats GG, Saldivar JC, Bacal J, Zeman MK, Kile AC, Hynes AM, Srivastava S, Nazmutdinova J, den Ouden K, Zagers MS, Foletto V, Verhaar MC, Miles C, Sayer JA, Cimprich KA, Giles RH.

J Clin Invest. 2015 Sep;125(9):3657-66. doi: 10.1172/JCI80657.

PMID:
26301811
19.

Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe.

Caspari T, Hilditch V.

PLoS One. 2015 Jul 1;10(7):e0130748. doi: 10.1371/journal.pone.0130748.

PMID:
26131711
20.

Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma.

Magnussen GI, Emilsen E, Giller Fleten K, Engesæter B, Nähse-Kumpf V, Fjær R, Slipicevic A, Flørenes VA.

BMC Cancer. 2015 Jun 10;15:462. doi: 10.1186/s12885-015-1474-8.

PMID:
26054341
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