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Items: 1 to 20 of 72


GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion.

Barbosa S, Carreira S, O'Hare P.

Mol Biol Cell. 2017 Jun 1;28(11):1565-1579. doi: 10.1091/mbc.E17-01-0075. Epub 2017 Apr 5.


Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation.

Zhao F, Wang N, Yi Y, Lin P, Tang K, Wang A, Jin Y.

PLoS One. 2016 Dec 14;11(12):e0168246. doi: 10.1371/journal.pone.0168246. eCollection 2016.


The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression.

Cui X, Cui M, Asada R, Kanemoto S, Saito A, Matsuhisa K, Kaneko M, Imaizumi K.

Sci Rep. 2016 Nov 17;6:37310. doi: 10.1038/srep37310.


A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway.

Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, Guo X, Xu S, Li T, Shao Q, Yan S, Li G.

Autophagy. 2016 Jul 2;12(7):1129-52. doi: 10.1080/15548627.2016.1178446. Epub 2016 May 10.


An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex.

Zhang P, Bai Y, Lu L, Li Y, Duan C.

Elife. 2016 Jan 14;5. pii: e08996. doi: 10.7554/eLife.08996.


OASIS modulates hypoxia pathway activity to regulate bone angiogenesis.

Cui M, Kanemoto S, Cui X, Kaneko M, Asada R, Matsuhisa K, Tanimoto K, Yoshimoto Y, Shukunami C, Imaizumi K.

Sci Rep. 2015 Nov 12;5:16455. doi: 10.1038/srep16455.


Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.

Kanemoto S, Kobayashi Y, Yamashita T, Miyamoto T, Cui M, Asada R, Cui X, Hino K, Kaneko M, Takai T, Matsuhisa K, Takahashi N, Imaizumi K.

J Cell Sci. 2015 Dec 1;128(23):4353-65. doi: 10.1242/jcs.176057. Epub 2015 Oct 26.


Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets.

Barbosa S, Carreira S, Bailey D, Abaitua F, O'Hare P.

Mol Biol Cell. 2015 Aug 15;26(16):2939-54. doi: 10.1091/mbc.E15-04-0247. Epub 2015 Jun 24.


Transcriptional regulation of secretory capacity by bZip transcription factors.

Fox RM, Andrew DJ.

Front Biol (Beijing). 2015 Feb 1;10(1):28-51.


Sensing nerve injury at the axonal ER: activated Luman/CREB3 serves as a novel axonally synthesized retrograde regeneration signal.

Ying Z, Misra V, Verge VM.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16142-7. doi: 10.1073/pnas.1407462111. Epub 2014 Oct 27.


Master regulator for chondrogenesis, Sox9, regulates transcriptional activation of the endoplasmic reticulum stress transducer BBF2H7/CREB3L2 in chondrocytes.

Hino K, Saito A, Kido M, Kanemoto S, Asada R, Takai T, Cui M, Cui X, Imaizumi K.

J Biol Chem. 2014 May 16;289(20):13810-20. doi: 10.1074/jbc.M113.543322. Epub 2014 Apr 6.


Increased susceptibility to dextran sulfate sodium-induced colitis in the endoplasmic reticulum stress transducer OASIS deficient mice.

Hino K, Saito A, Asada R, Kanemoto S, Imaizumi K.

PLoS One. 2014 Feb 3;9(2):e88048. doi: 10.1371/journal.pone.0088048. eCollection 2014.


Physiological functions of endoplasmic reticulum stress transducer OASIS in central nervous system.

Saito A.

Anat Sci Int. 2014 Jan;89(1):11-20. doi: 10.1007/s12565-013-0214-x. Epub 2013 Nov 16. Review.


An X-linked cobalamin disorder caused by mutations in transcriptional coregulator HCFC1.

Yu HC, Sloan JL, Scharer G, Brebner A, Quintana AM, Achilly NP, Manoli I, Coughlin CR 2nd, Geiger EA, Schneck U, Watkins D, Suormala T, Van Hove JL, Fowler B, Baumgartner MR, Rosenblatt DS, Venditti CP, Shaikh TH.

Am J Hum Genet. 2013 Sep 5;93(3):506-14. doi: 10.1016/j.ajhg.2013.07.022.


The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection.

Vogel JL, Kristie TM.

Viruses. 2013 May 22;5(5):1272-91. doi: 10.3390/v5051272. Review.


JAB1/CSN5 inhibits the activity of Luman/CREB3 by promoting its degradation.

DenBoer LM, Iyer A, McCluggage AR, Li Y, Martyn AC, Lu R.

Biochim Biophys Acta. 2013 Sep;1829(9):921-9. doi: 10.1016/j.bbagrm.2013.04.001. Epub 2013 Apr 11.


Expression pattern implicates a potential role for luman recruitment factor in the process of implantation in uteri and development of preimplantation embryos in mice.

Yang Y, Jin Y, Martyn AC, Lin P, Song Y, Chen F, Hu L, Cui C, Li X, Li Q, Lu R, Wang A.

J Reprod Dev. 2013;59(3):245-51. Epub 2013 Feb 12.


An orchestrated program regulating secretory pathway genes and cargos by the transmembrane transcription factor CREB-H.

Barbosa S, Fasanella G, Carreira S, Llarena M, Fox R, Barreca C, Andrew D, O'Hare P.

Traffic. 2013 Apr;14(4):382-98. doi: 10.1111/tra.12038. Epub 2013 Jan 24.


Luman/CREB3 recruitment factor regulates glucocorticoid receptor activity and is essential for prolactin-mediated maternal instinct.

Martyn AC, Choleris E, Gillis DJ, Armstrong JN, Amor TR, McCluggage AR, Turner PV, Liang G, Cai K, Lu R.

Mol Cell Biol. 2012 Dec;32(24):5140-50. doi: 10.1128/MCB.01142-12. Epub 2012 Oct 15.

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