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Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults.

Green CA, Scarselli E, Voysey M, Capone S, Vitelli A, Nicosia A, Cortese R, Thompson AJ, Sande CS, de Lara C, Klenerman P, Pollard AJ.

BMJ Open. 2015 Oct 28;5(10):e008748. doi: 10.1136/bmjopen-2015-008748.


Novel antigens for RSV vaccines.

Graham BS, Modjarrad K, McLellan JS.

Curr Opin Immunol. 2015 Aug;35:30-8. doi: 10.1016/j.coi.2015.04.005. Review.


Impaired immune response to vaccination against infection with human respiratory syncytial virus at advanced age.

Guichelaar T, Hoeboer J, Widjojoatmodjo MN, Reemers SS, van Els CA, Otten R, van Remmerden Y, Boes J, Luytjes W.

J Virol. 2014 Sep 1;88(17):9744-50. doi: 10.1128/JVI.01101-14.


Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh.

Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA.

J Infect Dis. 2014 Nov 15;210(10):1582-9. doi: 10.1093/infdis/jiu316.


Decrease in formalin-inactivated respiratory syncytial virus (FI-RSV) enhanced disease with RSV G glycoprotein peptide immunization in BALB/c mice.

Rey GU, Miao C, Caidi H, Trivedi SU, Harcourt JL, Tripp RA, Anderson LJ, Haynes LM.

PLoS One. 2013 Dec 23;8(12):e83075. doi: 10.1371/journal.pone.0083075.


Nanoparticle vaccines encompassing the respiratory syncytial virus (RSV) G protein CX3C chemokine motif induce robust immunity protecting from challenge and disease.

Jorquera PA, Choi Y, Oakley KE, Powell TJ, Boyd JG, Palath N, Haynes LM, Anderson LJ, Tripp RA.

PLoS One. 2013 Sep 10;8(9):e74905. doi: 10.1371/journal.pone.0074905.


A novel influenza virus hemagglutinin-respiratory syncytial virus (RSV) fusion protein subunit vaccine against influenza and RSV.

Turner TM, Jones LP, Tompkins SM, Tripp RA.

J Virol. 2013 Oct;87(19):10792-804. doi: 10.1128/JVI.01724-13.


An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice.

Cherukuri A, Stokes KL, Patton K, Kuo H, Sakamoto K, Lambert S, Stillman E, Moore ML, Lee S.

Immun Ageing. 2012 Oct 2;9(1):21. doi: 10.1186/1742-4933-9-21.


Antibodies to the central conserved region of respiratory syncytial virus (RSV) G protein block RSV G protein CX3C-CX3CR1 binding and cross-neutralize RSV A and B strains.

Choi Y, Mason CS, Jones LP, Crabtree J, Jorquera PA, Tripp RA.

Viral Immunol. 2012 Jun;25(3):193-203. doi: 10.1089/vim.2011.0094.


Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years.

Collins PL, Melero JA.

Virus Res. 2011 Dec;162(1-2):80-99. doi: 10.1016/j.virusres.2011.09.020. Review.


Respiratory syncytial virus vaccine: Is it coming?

Sales V, Wang EE.

Paediatr Child Health. 2003 Dec;8(10):605-8.


Respiratory syncytial virus vaccine development.

Murata Y.

Clin Lab Med. 2009 Dec;29(4):725-39. doi: 10.1016/j.cll.2009.07.004. Review.


Vaccination to induce antibodies blocking the CX3C-CX3CR1 interaction of respiratory syncytial virus G protein reduces pulmonary inflammation and virus replication in mice.

Zhang W, Choi Y, Haynes LM, Harcourt JL, Anderson LJ, Jones LP, Tripp RA.

J Virol. 2010 Jan;84(2):1148-57. doi: 10.1128/JVI.01755-09.


Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats.

Cseke G, Wright DW, Tollefson SJ, Johnson JE, Crowe JE Jr, Williams JV.

J Virol. 2007 Jan;81(2):698-707.


Parainfluenza virus type 3 expressing the native or soluble fusion (F) Protein of Respiratory Syncytial Virus (RSV) confers protection from RSV infection in African green monkeys.

Tang RS, MacPhail M, Schickli JH, Kaur J, Robinson CL, Lawlor HA, Guzzetta JM, Spaete RR, Haller AA.

J Virol. 2004 Oct;78(20):11198-207.


Animal pneumoviruses: molecular genetics and pathogenesis.

Easton AJ, Domachowske JB, Rosenberg HF.

Clin Microbiol Rev. 2004 Apr;17(2):390-412. Review.


Active immunization in the United States: developments over the past decade.

Dennehy PH.

Clin Microbiol Rev. 2001 Oct;14(4):872-908, table of contents. Review.


Respiratory syncytial virus infection in adults.

Falsey AR, Walsh EE.

Clin Microbiol Rev. 2000 Jul;13(3):371-84. Review.

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