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Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics.

Botham RC, Roth HS, Book AP, Roady PJ, Fan TM, Hergenrother PJ.

ACS Cent Sci. 2016 Aug 24;2(8):545-59. doi: 10.1021/acscentsci.6b00165.


EF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma.

Yin DL, Liang YJ, Zheng TS, Song RP, Wang JB, Sun BS, Pan SH, Qu LD, Liu JR, Jiang HC, Liu LX.

Sci Rep. 2016 Aug 30;6:32167. doi: 10.1038/srep32167.


Survivin: a unique target for tumor therapy.

Garg H, Suri P, Gupta JC, Talwar GP, Dubey S.

Cancer Cell Int. 2016 Jun 23;16:49. doi: 10.1186/s12935-016-0326-1. Review.


USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.

Engel K, Rudelius M, Slawska J, Jacobs L, Ahangarian Abhari B, Altmann B, Kurutz J, Rathakrishnan A, Fernández-Sáiz V, Brunner A, Targosz BS, Loewecke F, Gloeckner CJ, Ueffing M, Fulda S, Pfreundschuh M, Trümper L, Klapper W, Keller U, Jost PJ, Rosenwald A, Peschel C, Bassermann F.

EMBO Mol Med. 2016 Aug 1;8(8):851-62. doi: 10.15252/emmm.201506047.


Advances in Gene Therapy for Diseases of the Eye.

Petit L, Khanna H, Punzo C.

Hum Gene Ther. 2016 Aug;27(8):563-79. doi: 10.1089/hum.2016.040.


The beneficial role of proteolysis in skeletal muscle growth and stress adaptation.

Bell RA, Al-Khalaf M, Megeney LA.

Skelet Muscle. 2016 Apr 6;6:16. doi: 10.1186/s13395-016-0086-6. Review. Erratum in: Skelet Muscle. 2016;6:19.


Apoptosis through Death Receptors in Temporal Lobe Epilepsy-Associated Hippocampal Sclerosis.

Teocchi MA, D'Souza-Li L.

Mediators Inflamm. 2016;2016:8290562. doi: 10.1155/2016/8290562.


The Role of Gastrin and CCK Receptors in Pancreatic Cancer and other Malignancies.

Smith JP, Fonkoua LK, Moody TW.

Int J Biol Sci. 2016 Jan 28;12(3):283-91. doi: 10.7150/ijbs.14952. Review.


Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model.

Parajuli KR, Zhang Q, Liu S, You Z.

Oncotarget. 2016 Mar 1;7(9):10616-26. doi: 10.18632/oncotarget.7055.


Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?

Baig S, Seevasant I, Mohamad J, Mukheem A, Huri HZ, Kamarul T.

Cell Death Dis. 2016 Jan 14;7:e2058. doi: 10.1038/cddis.2015.275. Review.


Sox11 Reduces Caspase-6 Cleavage and Activity.

Waldron-Roby E, Hoerauf J, Arbez N, Zhu S, Kulcsar K, Ross CA.

PLoS One. 2015 Oct 27;10(10):e0141439. doi: 10.1371/journal.pone.0141439.


Inhibitor of apoptosis proteins as intracellular signaling intermediates.

Kocab AJ, Duckett CS.

FEBS J. 2016 Jan;283(2):221-31. doi: 10.1111/febs.13554. Review.


Regulation of Cell Death by IAPs and Their Antagonists.

Vasudevan D, Ryoo HD.

Curr Top Dev Biol. 2015;114:185-208. doi: 10.1016/bs.ctdb.2015.07.026. Review.


Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine.

Pakavathkumar P, Sharma G, Kaushal V, Foveau B, LeBlanc AC.

Sci Rep. 2015 Sep 24;5:13730. doi: 10.1038/srep13730.


TRIP-Br1 oncoprotein inhibits autophagy, apoptosis, and necroptosis under nutrient/serum-deprived condition.

Jung S, Li C, Duan J, Lee S, Kim K, Park Y, Yang Y, Kim KI, Lim JS, Cheon CI, Kang YS, Lee MS.

Oncotarget. 2015 Oct 6;6(30):29060-75. doi: 10.18632/oncotarget.5072.


A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy.

Chaudhary AK, Yadav N, Bhat TA, O'Malley J, Kumar S, Chandra D.

Drug Discov Today. 2016 Jan;21(1):38-47. doi: 10.1016/j.drudis.2015.07.014. Review.


Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP).

Valenzuela MM, Ferguson Bennit HR, Gonda A, Diaz Osterman CJ, Hibma A, Khan S, Wall NR.

Cancer Microenviron. 2015 Aug;8(2):65-73. doi: 10.1007/s12307-015-0167-9.


Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.

Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK.

Mol Syst Biol. 2015 May 7;11(5):803. doi: 10.15252/msb.20145584.

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