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Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ.

Chebaro Y, Sirigu S, Amal I, Lutzing R, Stote RH, Rochette-Egly C, Rochel N, Dejaegere A.

PLoS One. 2017 Jan 26;12(1):e0171043. doi: 10.1371/journal.pone.0171043. eCollection 2017.


Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality.

Li L, Qi X, Sun W, Abdel-Azim H, Lou S, Zhu H, Prasadarao NV, Zhou A, Shimada H, Shudo K, Kim YM, Khazal S, He Q, Warburton D, Wu L.

EMBO Mol Med. 2016 Nov 2;8(11):1340-1359. doi: 10.15252/emmm.201606434. Print 2016 Nov.


Phosphoproteome and Transcriptome of RA-Responsive and RA-Resistant Breast Cancer Cell Lines.

Carrier M, Joint M, Lutzing R, Page A, Rochette-Egly C.

PLoS One. 2016 Jun 30;11(6):e0157290. doi: 10.1371/journal.pone.0157290. eCollection 2016.


Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer.

Patel H, Abduljabbar R, Lai CF, Periyasamy M, Harrod A, Gemma C, Steel JH, Patel N, Busonero C, Jerjees D, Remenyi J, Smith S, Gomm JJ, Magnani L, Győrffy B, Jones LJ, Fuller-Pace F, Shousha S, Buluwela L, Rakha EA, Ellis IO, Coombes RC, Ali S.

Clin Cancer Res. 2016 Dec 1;22(23):5929-5938. Epub 2016 Jun 14.


Molecular Mechanisms of Retinoid Receptors in Diabetes-Induced Cardiac Remodeling.

Pan J, Guleria RS, Zhu S, Baker KM.

J Clin Med. 2014 Jun 4;3(2):566-94. doi: 10.3390/jcm3020566. Review.


Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.

Helzer KT, Hooper C, Miyamoto S, Alarid ET.

J Mol Endocrinol. 2015 Jun;54(3):R151-67. doi: 10.1530/JME-14-0308. Epub 2015 May 5. Review.


Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors.

Bendris N, Lemmers B, Blanchard JM.

Cell Cycle. 2015;14(12):1786-98. doi: 10.1080/15384101.2014.998085. Review.


TFIIH subunit alterations causing xeroderma pigmentosum and trichothiodystrophy specifically disturb several steps during transcription.

Singh A, Compe E, Le May N, Egly JM.

Am J Hum Genet. 2015 Feb 5;96(2):194-207. doi: 10.1016/j.ajhg.2014.12.012. Epub 2015 Jan 22.


Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP.

Cell Metab. 2013 Nov 5;18(5):660-71. doi: 10.1016/j.cmet.2013.10.005.


The lost intrinsic fragmentation of MAT1 protein during granulopoiesis promotes the growth and metastasis of leukemic myeloblasts.

Lou S, Liu G, Shimada H, Yang X, He Q, Wu L.

Stem Cells. 2013 Sep;31(9):1942-53. doi: 10.1002/stem.1444.


The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.

Flajollet S, Rachez C, Ploton M, Schulz C, Gallais R, Métivier R, Pawlak M, Leray A, Issulahi AA, Héliot L, Staels B, Salbert G, Lefebvre P.

PLoS One. 2013 Jun 10;8(6):e64880. doi: 10.1371/journal.pone.0064880. Print 2013.


Phosphorylation of the retinoic acid receptor alpha induces a mechanical allosteric regulation and changes in internal dynamics.

Chebaro Y, Amal I, Rochel N, Rochette-Egly C, Stote RH, Dejaegere A.

PLoS Comput Biol. 2013 Apr;9(4):e1003012. doi: 10.1371/journal.pcbi.1003012. Epub 2013 Apr 18.


Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications.

Kim TH, Kim MY, Jo SH, Park JM, Ahn YH.

Yonsei Med J. 2013 May 1;54(3):545-59. doi: 10.3349/ymj.2013.54.3.545. Review.


Vitamin A and retinoid signaling: genomic and nongenomic effects.

Al Tanoury Z, Piskunov A, Rochette-Egly C.

J Lipid Res. 2013 Jul;54(7):1761-75. doi: 10.1194/jlr.R030833. Epub 2013 Feb 24. Review.


ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities.

Abdulrahman W, Iltis I, Radu L, Braun C, Maglott-Roth A, Giraudon C, Egly JM, Poterszman A.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E633-42. doi: 10.1073/pnas.1213981110. Epub 2013 Feb 4.


Retinoid-regulated FGF8f secretion by osteoblasts bypasses retinoid stimuli to mediate granulocytic differentiation of myeloid leukemia cells.

Chaudhry P, Yang X, Wagner M, Jong A, Wu L.

Mol Cancer Ther. 2012 Feb;11(2):267-76. doi: 10.1158/1535-7163.MCT-11-0584. Epub 2011 Dec 1.


High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling.

Singh AB, Guleria RS, Nizamutdinova IT, Baker KM, Pan J.

J Cell Physiol. 2012 Jun;227(6):2632-44. doi: 10.1002/jcp.23005.


Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1.

Moriel-Carretero M, Tous C, Aguilera A.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15300-5. doi: 10.1073/pnas.1107425108. Epub 2011 Aug 29.


The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process.

Chymkowitch P, Le May N, Charneau P, Compe E, Egly JM.

EMBO J. 2011 Feb 2;30(3):468-79. doi: 10.1038/emboj.2010.337. Epub 2010 Dec 14.

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