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Items: 1 to 20 of 125


Abnormal CFTR Affects Glucagon Production by Islet α Cells in Cystic Fibrosis and Polycystic Ovarian Syndrome.

Huang WQ, Guo JH, Yuan C, Cui YG, Diao FY, Yu MK, Liu JY, Ruan YC, Chan HC.

Front Physiol. 2017 Nov 17;8:835. doi: 10.3389/fphys.2017.00835. eCollection 2017.


Reprogramming human gallbladder cells into insulin-producing β-like cells.

Galivo F, Benedetti E, Wang Y, Pelz C, Schug J, Kaestner KH, Grompe M.

PLoS One. 2017 Aug 16;12(8):e0181812. doi: 10.1371/journal.pone.0181812. eCollection 2017.


β-Cell Replacement Strategies: The Increasing Need for a "β-Cell Dogma".

Vieira A, Druelle N, Avolio F, Napolitano T, Navarro-Sanz S, Silvano S, Collombat P.

Front Genet. 2017 Jun 6;8:75. doi: 10.3389/fgene.2017.00075. eCollection 2017. Review.


Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.

Sinagoga KL, Stone WJ, Schiesser JV, Schweitzer JI, Sampson L, Zheng Y, Wells JM.

Development. 2017 Jul 1;144(13):2402-2414. doi: 10.1242/dev.146316. Epub 2017 Jun 2.


The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.

Mitchell RK, Nguyen-Tu MS, Chabosseau P, Callingham RM, Pullen TJ, Cheung R, Leclerc I, Hodson DJ, Rutter GA.

J Biol Chem. 2017 May 26;292(21):8892-8906. doi: 10.1074/jbc.M117.784629. Epub 2017 Apr 4.


The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.

Yang YP, Magnuson MA, Stein R, Wright CV.

Development. 2017 Jan 15;144(2):248-257. doi: 10.1242/dev.143123. Epub 2016 Dec 19.


The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.

Bhat N, Park J, Zoghbi HY, Arthur JS, Zaret KS.

PLoS One. 2016 Dec 14;11(12):e0166703. doi: 10.1371/journal.pone.0166703. eCollection 2016.


PAX6 maintains β cell identity by repressing genes of alternative islet cell types.

Swisa A, Avrahami D, Eden N, Zhang J, Feleke E, Dahan T, Cohen-Tayar Y, Stolovich-Rain M, Kaestner KH, Glaser B, Ashery-Padan R, Dor Y.

J Clin Invest. 2017 Jan 3;127(1):230-243. doi: 10.1172/JCI88015. Epub 2016 Dec 12.


Stem Cells in the Treatment of Insulin-Dependent Diabetes Mellitus.

Borisov MA, Petrakova OS, Gvazava IG, Kalistratova EN, Vasiliev AV.

Acta Naturae. 2016 Jul-Sep;8(3):31-43.


Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors.

Koblas T, Leontovyc I, Loukotova S, Kosinova L, Saudek F.

Mol Ther Nucleic Acids. 2016 May 17;5:e320. doi: 10.1038/mtna.2016.33.


Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes.

Ackermann AM, Wang Z, Schug J, Naji A, Kaestner KH.

Mol Metab. 2016 Jan 11;5(3):233-44. doi: 10.1016/j.molmet.2016.01.002. eCollection 2016 Mar.


Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.

Teo AK, Lau HH, Valdez IA, Dirice E, Tjora E, Raeder H, Kulkarni RN.

Stem Cell Reports. 2016 Mar 8;6(3):357-67. doi: 10.1016/j.stemcr.2016.01.007. Epub 2016 Feb 11.


Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker.

Ahmad Z, Rafeeq M, Collombat P, Mansouri A.

PLoS One. 2015 Dec 11;10(12):e0144597. doi: 10.1371/journal.pone.0144597. eCollection 2015.


The Role of ARX in Human Pancreatic Endocrine Specification.

Gage BK, Asadi A, Baker RK, Webber TD, Wang R, Itoh M, Hayashi M, Miyata R, Akashi T, Kieffer TJ.

PLoS One. 2015 Dec 3;10(12):e0144100. doi: 10.1371/journal.pone.0144100. eCollection 2015.


Transcription factor regulation of pancreatic organogenesis, differentiation and maturation.

Dassaye R, Naidoo S, Cerf ME.

Islets. 2016;8(1):13-34. doi: 10.1080/19382014.2015.1075687. Epub 2015 Sep 24. Review.


Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators.

Sun J, Rockowitz S, Chauss D, Wang P, Kantorow M, Zheng D, Cvekl A.

Mol Vis. 2015 Aug 28;21:955-73. eCollection 2015.


Pancreatic islet cell development and regeneration.

Romer AI, Sussel L.

Curr Opin Endocrinol Diabetes Obes. 2015 Aug;22(4):255-64. doi: 10.1097/MED.0000000000000174. Review.


Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction.

Pauerstein PT, Sugiyama T, Stanley SE, McLean GW, Wang J, Martín MG, Kim SK.

Diabetes. 2015 Aug;64(8):3037-49. doi: 10.2337/db15-0042. Epub 2015 Apr 21.


Role of pancreatic transcription factors in maintenance of mature β-cell function.

Kaneto H, Matsuoka TA.

Int J Mol Sci. 2015 Mar 18;16(3):6281-97. doi: 10.3390/ijms16036281. Review.


Role of transcription factors in the transdifferentiation of pancreatic islet cells.

van der Meulen T, Huising MO.

J Mol Endocrinol. 2015 Apr;54(2):R103-17. doi: 10.1530/JME-14-0290. Review.

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