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Items: 1 to 20 of 28


The role of ATP-dependent machines in regulating genome topology.

Hauk G, Berger JM.

Curr Opin Struct Biol. 2016 Feb;36:85-96. doi: 10.1016/ Epub 2016 Jan 29. Review.


A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.

Huang H, Strømme CB, Saredi G, Hödl M, Strandsby A, González-Aguilera C, Chen S, Groth A, Patel DJ.

Nat Struct Mol Biol. 2015 Aug;22(8):618-26. doi: 10.1038/nsmb.3055. Epub 2015 Jul 13.


Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication.

Hesketh EL, Knight JR, Wilson RH, Chong JP, Coverley D.

Cell Cycle. 2015;14(3):333-41. doi: 10.4161/15384101.2014.980647.


MicroRNA-31 suppresses medulloblastoma cell growth by inhibiting DNA replication through minichromosome maintenance 2.

Jin Y, Xiong A, Zhang Z, Li S, Huang H, Yu TT, Cao X, Cheng SY.

Oncotarget. 2014 Jul 15;5(13):4821-33.


Relationship between DNA replication and the nuclear matrix.

Wilson RH, Coverley D.

Genes Cells. 2013 Jan;18(1):17-31. doi: 10.1111/gtc.12010. Epub 2012 Nov 8. Review.


Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency.

Gineau L, Cognet C, Kara N, Lach FP, Dunne J, Veturi U, Picard C, Trouillet C, Eidenschenk C, Aoufouchi S, Alcaïs A, Smith O, Geissmann F, Feighery C, Abel L, Smogorzewska A, Stillman B, Vivier E, Casanova JL, Jouanguy E.

J Clin Invest. 2012 Mar;122(3):821-32. doi: 10.1172/JCI61014. Epub 2012 Feb 22.


Cyclin A promotes S-phase entry via interaction with the replication licensing factor Mcm7.

Chibazakura T, Kamachi K, Ohara M, Tane S, Yoshikawa H, Roberts JM.

Mol Cell Biol. 2011 Jan;31(2):248-55. doi: 10.1128/MCB.00630-10. Epub 2010 Nov 15.


Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

Chuang CH, Wallace MD, Abratte C, Southard T, Schimenti JC.

PLoS Genet. 2010 Sep 9;6(9):e1001110. doi: 10.1371/journal.pgen.1001110.


Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.

Qian Z, Leung-Pineda V, Xuan B, Piwnica-Worms H, Yu D.

PLoS Pathog. 2010 Mar 19;6(3):e1000814. doi: 10.1371/journal.ppat.1000814.


Udu deficiency activates DNA damage checkpoint.

Lim CH, Chong SW, Jiang YJ.

Mol Biol Cell. 2009 Oct;20(19):4183-93. doi: 10.1091/mbc.E09-02-0109. Epub 2009 Aug 5.


Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.

Kudoh A, Daikoku T, Ishimi Y, Kawaguchi Y, Shirata N, Iwahori S, Isomura H, Tsurumi T.

J Virol. 2006 Oct;80(20):10064-72.


Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T.

EMBO J. 2006 Mar 8;25(5):1126-36. Epub 2006 Feb 16.


The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Ying CY, Gautier J.

EMBO J. 2005 Dec 21;24(24):4334-44. Epub 2005 Nov 24.


Minichromosome maintenance protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma.

Schrader C, Janssen D, Klapper W, Siebmann JU, Meusers P, Brittinger G, Kneba M, Tiemann M, Parwaresch R.

Br J Cancer. 2005 Oct 17;93(8):939-45.


How many mutant p53 molecules are needed to inactivate a tetramer?

Chan WM, Siu WY, Lau A, Poon RY.

Mol Cell Biol. 2004 Apr;24(8):3536-51.


Eukaryotic MCM proteins: beyond replication initiation.

Forsburg SL.

Microbiol Mol Biol Rev. 2004 Mar;68(1):109-31. Review.


Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner.

Miccoli L, Biard DS, Frouin I, Harper F, Maga G, Angulo JF.

Nucleic Acids Res. 2003 Jul 15;31(14):4162-75.


Human Mcm proteins at a replication origin during the G1 to S phase transition.

Schaarschmidt D, Ladenburger EM, Keller C, Knippers R.

Nucleic Acids Res. 2002 Oct 1;30(19):4176-85.

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