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Profile of William Kaelin, Peter Ratcliffe, and Greg Semenza, 2016 Albert Lasker Basic Medical Research Awardees.

Johnson RS.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):13938-13940. No abstract available.


The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease.

Woeller CF, Roztocil E, Hammond CL, Feldon SE, Phipps RP.

Am J Pathol. 2016 Dec;186(12):3189-3202. doi: 10.1016/j.ajpath.2016.08.017.


The role of HIFs in ischemia-reperfusion injury.

Howell NJ, Tennant DA.

Hypoxia (Auckl). 2014 Jul 30;2:107-115. Review.


Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β.

Mennerich D, Dimova EY, Kietzmann T.

Hypoxia (Auckl). 2014 Apr 30;2:35-45. Review.


Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility.

Taylor SE, Bagnall J, Mason D, Levy R, Fernig DG, See V.

Open Biol. 2016 Sep;6(9). pii: 160195.


William Kaelin, Peter Ratcliffe, and Gregg Semenza receive the 2016 Albert Lasker Basic Medical Research Award.

Hurst JH.

J Clin Invest. 2016 Oct 3;126(10):3628-3638. doi: 10.1172/JCI90055. No abstract available.


Obstructive Sleep Apnea and Circulating Potassium Channel Levels.

Jiang N, Zhou A, Prasad B, Zhou L, Doumit J, Shi G, Imran H, Kaseer B, Millman R, Dudley SC Jr.

J Am Heart Assoc. 2016 Aug 19;5(8). pii: e003666. doi: 10.1161/JAHA.116.003666.


Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk.

Kandalepas PC, Mitchell JW, Gillette MU.

PLoS One. 2016 Jun 30;11(6):e0157824. doi: 10.1371/journal.pone.0157824.


PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia.

Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza GL.

Oncotarget. 2016 Feb 9;7(6):6379-97. doi: 10.18632/oncotarget.7142.


Circadian metabolism in the light of evolution.

Gerhart-Hines Z, Lazar MA.

Endocr Rev. 2015 Jun;36(3):289-304. doi: 10.1210/er.2015-1007. Review.


Overexpression of HIF-2α in pancreatic β cells does not alter glucose homeostasis.

Brunt JJ, Shi SY, Schroer SA, Sivasubramaniyam T, Cai EP, Woo M.

Islets. 2014;6(5-6):e1006075. doi: 10.1080/19382014.2015.1006075.


The role of hypoxia-inducible factor-2 in digestive system cancers.

Zhao J, Du F, Shen G, Zheng F, Xu B.

Cell Death Dis. 2015 Jan 15;6:e1600. doi: 10.1038/cddis.2014.565. Review.


NPAS1 represses the generation of specific subtypes of cortical interneurons.

Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL.

Neuron. 2014 Dec 3;84(5):940-53. doi: 10.1016/j.neuron.2014.10.040.


The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90.

Tsuji N, Fukuda K, Nagata Y, Okada H, Haga A, Hatakeyama S, Yoshida S, Okamoto T, Hosaka M, Sekine K, Ohtaka K, Yamamoto S, Otaka M, Grave E, Itoh H.

FEBS Open Bio. 2014 Sep 16;4:796-803. doi: 10.1016/j.fob.2014.09.003.


A mammalian circadian clock model incorporating daytime expression elements.

Jolley CC, Ukai-Tadenuma M, Perrin D, Ueda HR.

Biophys J. 2014 Sep 16;107(6):1462-73. doi: 10.1016/j.bpj.2014.07.022.


Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming.

Zwaans BM, Lombard DB.

Dis Model Mech. 2014 Sep;7(9):1023-32. doi: 10.1242/dmm.016287. Review.


Brain and muscle Arnt-like 1 is a key regulator of myogenesis.

Chatterjee S, Nam D, Guo B, Kim JM, Winnier GE, Lee J, Berdeaux R, Yechoor VK, Ma K.

J Cell Sci. 2013 May 15;126(Pt 10):2213-24. doi: 10.1242/jcs.120519.


The "Sharp" blade against HIF-mediated metastasis.

Amelio I, Melino G.

Cell Cycle. 2012 Dec 15;11(24):4530-5. doi: 10.4161/cc.22820.


The role of hypoxia-inducible factors in oxygen sensing by the carotid body.

Semenza GL, Prabhakar NR.

Adv Exp Med Biol. 2012;758:1-5. doi: 10.1007/978-94-007-4584-1_1. Review.

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