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Items: 12


Physiological Roles of DNA Double-Strand Breaks.

Khan FA, Ali SO.

J Nucleic Acids. 2017;2017:6439169. doi: 10.1155/2017/6439169. Epub 2017 Oct 18. Review.


Topoisomerase II╬▓ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs.

Kenig S, Faoro V, Bourkoula E, Podergajs N, Ius T, Vindigni M, Skrap M, Lah T, Cesselli D, Storici P, Vindigni A.

Cancer Cell Int. 2016 Jul 26;16:58. doi: 10.1186/s12935-016-0339-9. eCollection 2016.


The use of divalent metal ions by type II topoisomerases.

Deweese JE, Osheroff N.

Metallomics. 2010 Jul;2(7):450-9. doi: 10.1039/c003759a. Epub 2010 May 21. Review.


Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.

Deweese JE, Burch AM, Burgin AB, Osheroff N.

Biochemistry. 2009 Mar 10;48(9):1862-9. doi: 10.1021/bi8023256.


The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing.

Deweese JE, Osheroff N.

Nucleic Acids Res. 2009 Feb;37(3):738-48. doi: 10.1093/nar/gkn937. Epub 2008 Nov 28. Review.


(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases.

Bandele OJ, Osheroff N.

Chem Res Toxicol. 2008 Apr;21(4):936-43. doi: 10.1021/tx700434v. Epub 2008 Feb 23.


DNA topoisomerase II, genotoxicity, and cancer.

McClendon AK, Osheroff N.

Mutat Res. 2007 Oct 1;623(1-2):83-97. Epub 2007 Jul 3. Review.


Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1.

Wyles JP, Wu Z, Mirski SE, Cole SP.

Nucleic Acids Res. 2007;35(12):4076-85. Epub 2007 Jun 12.


Bioflavonoids as poisons of human topoisomerase II alpha and II beta.

Bandele OJ, Osheroff N.

Biochemistry. 2007 May 22;46(20):6097-108. Epub 2007 Apr 26.


The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway.

Xiao H, Mao Y, Desai SD, Zhou N, Ting CY, Hwang J, Liu LF.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3239-44. Epub 2003 Mar 10.


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