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Items: 16


Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation.

Ye Q, Yang Y, van Staalduinen L, Crawley SW, Liu L, Brennan S, Côté GP, Jia Z.

Sci Rep. 2016 May 23;6:26634. doi: 10.1038/srep26634.


Characterization of the Catalytic and Nucleotide Binding Properties of the α-Kinase Domain of Dictyostelium Myosin-II Heavy Chain Kinase A.

Yang Y, Ye Q, Jia Z, Côté GP.

J Biol Chem. 2015 Sep 25;290(39):23935-46. doi: 10.1074/jbc.M115.672410. Epub 2015 Aug 10.


TRPM7, the cytoskeleton and neuronal death.

Asrar S, Aarts M.

Channels (Austin). 2013 Jan 1;7(1):6-16. doi: 10.4161/chan.22824. Epub 2012 Dec 17. Review.


Autophosphorylation activates Dictyostelium myosin II heavy chain kinase A by providing a ligand for an allosteric binding site in the alpha-kinase domain.

Crawley SW, Gharaei MS, Ye Q, Yang Y, Raveh B, London N, Schueler-Furman O, Jia Z, Côté GP.

J Biol Chem. 2011 Jan 28;286(4):2607-16. doi: 10.1074/jbc.M110.177014. Epub 2010 Nov 11.


Crystal structure of the alpha-kinase domain of Dictyostelium myosin heavy chain kinase A.

Ye Q, Crawley SW, Yang Y, Côté GP, Jia Z.

Sci Signal. 2010 Mar 2;3(111):ra17. doi: 10.1126/scisignal.2000525.


Conformational preference of ChaK1 binding peptides: a molecular dynamics study.

Zhang J, King CA, Dalby K, Ren P.

PMC Biophys. 2010 Jan 21;3(1):2. doi: 10.1186/1757-5036-3-2.


The alpha-kinase family: an exceptional branch on the protein kinase tree.

Middelbeek J, Clark K, Venselaar H, Huynen MA, van Leeuwen FN.

Cell Mol Life Sci. 2010 Mar;67(6):875-90. doi: 10.1007/s00018-009-0215-z. Epub 2009 Dec 12. Review.


The long and arduous road to CRAC.

Vig M, Kinet JP.

Cell Calcium. 2007 Aug;42(2):157-62. Epub 2007 May 22. Review.


Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium.

Yumura S, Yoshida M, Betapudi V, Licate LS, Iwadate Y, Nagasaki A, Uyeda TQ, Egelhoff TT.

Mol Biol Cell. 2005 Sep;16(9):4256-66. Epub 2005 Jun 29.


Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms.

De La Roche MA, Smith JL, Rico M, Carrasco S, Merida I, Licate L, Côté GP, Egelhoff TT.

Biochem J. 2002 Dec 15;368(Pt 3):809-15.


Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin-independent activity.

Diggle TA, Subkhankulova T, Lilley KS, Shikotra N, Willis AE, Redpath NT.

Biochem J. 2001 Feb 1;353(Pt 3):621-6.


The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms.

Plowman GD, Sudarsanam S, Bingham J, Whyte D, Hunter T.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13603-10. Review.


Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.

Ryazanov AG, Ward MD, Mendola CE, Pavur KS, Dorovkov MV, Wiedmann M, Erdjument-Bromage H, Tempst P, Parmer TG, Prostko CR, Germino FJ, Hait WN.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):4884-9.

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