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Items: 1 to 20 of 29

1.

The α5 subunit containing GABAA receptors contribute to chronic pain.

Bravo-Hernández M, Corleto JA, Barragán-Iglesias P, González-Ramírez R, Pineda-Farias JB, Felix R, Calcutt NA, Delgado-Lezama R, Marsala M, Granados-Soto V.

Pain. 2016 Mar;157(3):613-26. doi: 10.1097/j.pain.0000000000000410.

2.

Hippocampal sharp wave-ripple: A cognitive biomarker for episodic memory and planning.

Buzsáki G.

Hippocampus. 2015 Oct;25(10):1073-188. doi: 10.1002/hipo.22488. Review.

3.

Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors.

Fischell J, Van Dyke AM, Kvarta MD, LeGates TA, Thompson SM.

Neuropsychopharmacology. 2015 Oct;40(11):2499-509. doi: 10.1038/npp.2015.112. Epub 2015 Apr 22.

4.

Neurosteroids increase tonic GABAergic inhibition in the lateral section of the central amygdala in mice.

Romo-Parra H, Blaesse P, Sosulina L, Pape HC.

J Neurophysiol. 2015 May 1;113(9):3421-31. doi: 10.1152/jn.00045.2015. Epub 2015 Mar 18.

5.

Sustained increase in α5GABAA receptor function impairs memory after anesthesia.

Zurek AA, Yu J, Wang DS, Haffey SC, Bridgwater EM, Penna A, Lecker I, Lei G, Chang T, Salter EW, Orser BA.

J Clin Invest. 2014 Dec;124(12):5437-41. doi: 10.1172/JCI76669. Epub 2014 Nov 3.

6.

Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.

Seifi M, Brown JF, Mills J, Bhandari P, Belelli D, Lambert JJ, Rudolph U, Swinny JD.

J Neurosci. 2014 Jul 30;34(31):10361-78. doi: 10.1523/JNEUROSCI.0441-14.2014.

7.

New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways.

Perez SM, Lodge DJ.

Drug Des Devel Ther. 2014 Jul 2;8:887-96. doi: 10.2147/DDDT.S42708. eCollection 2014 Jul 2. Review.

8.

Deficient tonic GABAergic conductance and synaptic balance in the fragile X syndrome amygdala.

Martin BS, Corbin JG, Huntsman MM.

J Neurophysiol. 2014 Aug 15;112(4):890-902. doi: 10.1152/jn.00597.2013. Epub 2014 May 21.

9.

Methods for recording and measuring tonic GABAA receptor-mediated inhibition.

Bright DP, Smart TG.

Front Neural Circuits. 2013 Dec 5;7:193. doi: 10.3389/fncir.2013.00193. Review.

10.
11.

Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations.

Rae CD, Davidson JE, Maher AD, Rowlands BD, Kashem MA, Nasrallah FA, Rallapalli SK, Cook JM, Balcar VJ.

J Neurochem. 2014 Apr;129(2):304-14. doi: 10.1111/jnc.12634. Epub 2013 Dec 18.

12.

Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.

Carver CM, Reddy DS.

Psychopharmacology (Berl). 2013 Nov;230(2):151-88. doi: 10.1007/s00213-013-3276-5. Epub 2013 Sep 27. Review. Erratum in: Psychopharmacology (Berl). 2013 Nov;230(2):189.

13.

Potentiation of GABAA receptor activity by volatile anaesthetics is reduced by α5GABAA receptor-preferring inverse agonists.

Lecker I, Yin Y, Wang DS, Orser BA.

Br J Anaesth. 2013 Jun;110 Suppl 1:i73-81. doi: 10.1093/bja/aet038. Epub 2013 Mar 27.

14.

Enhancing the function of alpha5-subunit-containing GABAA receptors promotes action potential firing of neocortical neurons during up-states.

Drexler B, Zinser S, Huang S, Poe MM, Rudolph U, Cook JM, Antkowiak B.

Eur J Pharmacol. 2013 Mar 5;703(1-3):18-24. doi: 10.1016/j.ejphar.2013.01.034. Epub 2013 Feb 1.

15.

PWZ-029, an inverse agonist selective for α₅ GABAA receptors, improves object recognition, but not water-maze memory in normal and scopolamine-treated rats.

Milić M, Timić T, Joksimović S, Biawat P, Rallapalli S, Divljaković J, Radulović T, Cook JM, Savić MM.

Behav Brain Res. 2013 Mar 15;241:206-13. doi: 10.1016/j.bbr.2012.12.016. Epub 2012 Dec 20.

16.

Memory deficits induced by inflammation are regulated by α5-subunit-containing GABAA receptors.

Wang DS, Zurek AA, Lecker I, Yu J, Abramian AM, Avramescu S, Davies PA, Moss SJ, Lu WY, Orser BA.

Cell Rep. 2012 Sep 27;2(3):488-96. doi: 10.1016/j.celrep.2012.08.022. Epub 2012 Sep 20.

17.

Age-dependent remodelling of inhibitory synapses onto hippocampal CA1 oriens-lacunosum moleculare interneurons.

Salesse C, Mueller CL, Chamberland S, Topolnik L.

J Physiol. 2011 Oct 15;589(Pt 20):4885-901. doi: 10.1113/jphysiol.2011.215244. Epub 2011 Aug 8.

18.

A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia.

Gill KM, Lodge DJ, Cook JM, Aras S, Grace AA.

Neuropsychopharmacology. 2011 Aug;36(9):1903-11. doi: 10.1038/npp.2011.76. Epub 2011 May 11.

19.

Homeostatic regulation of synaptic excitability: tonic GABA(A) receptor currents replace I(h) in cortical pyramidal neurons of HCN1 knock-out mice.

Chen X, Shu S, Schwartz LC, Sun C, Kapur J, Bayliss DA.

J Neurosci. 2010 Feb 17;30(7):2611-22. doi: 10.1523/JNEUROSCI.3771-09.2010.

20.

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