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PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target.

Pleniceanu O, Shukrun R, Omer D, Vax E, Kanter I, Dziedzic K, Pode-Shakked N, Mark-Daniei M, Pri-Chen S, Gnatek Y, Alfandary H, Varda-Bloom N, Bar-Lev DD, Bollag N, Shtainfeld R, Armon L, Urbach A, Kalisky T, Nagler A, Harari-Steinberg O, Arbiser JL, Dekel B.

EMBO Mol Med. 2017 Apr;9(4):508-530. doi: 10.15252/emmm.201506111.


Do Mesenchymal Stem Cells Derived From Atypical Lipomatous Tumors Have Greater Differentiation Potency Than Cells From Normal Adipose Tissues?

Inatani H, Yamamoto N, Hayashi K, Kimura H, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Yamada S, Asai K, Otsuka T, Tsuchiya H.

Clin Orthop Relat Res. 2017 Jun;475(6):1693-1701. doi: 10.1007/s11999-017-5259-z. Epub 2017 Feb 2.


PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs.

Vella S, Conaldi PG, Florio T, Pagano A.

PPAR Res. 2016;2016:3038164. Epub 2016 Oct 5. Review.


Current classification, treatment options, and new perspectives in the management of adipocytic sarcomas.

De Vita A, Mercatali L, Recine F, Pieri F, Riva N, Bongiovanni A, Liverani C, Spadazzi C, Miserocchi G, Amadori D, Ibrahim T.

Onco Targets Ther. 2016 Oct 11;9:6233-6246. eCollection 2016. Review.


Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone.

Cheng WY, Huynh H, Chen P, Peña-Llopis S, Wan Y.

Elife. 2016 Oct 3;5. pii: e18501. doi: 10.7554/eLife.18501.


Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy.

Park H, Ko SH, Lee JM, Park JH, Choi YH.

Yonsei Med J. 2016 Nov;57(6):1494-9. doi: 10.3349/ymj.2016.57.6.1494.


Commonalities in the Association between PPARG and Vitamin D Related with Obesity and Carcinogenesis.

Bandera Merchan B, Tinahones FJ, Macías-González M.

PPAR Res. 2016;2016:2308249. doi: 10.1155/2016/2308249. Epub 2016 Aug 8. Review.


Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice.

Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, Durkes A, Elzey BD, Andrisani OM, Bidwell CA, Freeman JL, Konieczny SF, Kuang S.

J Exp Med. 2016 Sep 19;213(10):2019-37. doi: 10.1084/jem.20160157. Epub 2016 Aug 29.


Clinical relevance of peroxisome proliferator-activated receptor-gamma expression in myxoid liposarcoma.

Takeuchi A, Yamamoto N, Shirai T, Hayashi K, Miwa S, Munesue S, Yamamoto Y, Tsuchiya H.

BMC Cancer. 2016 Jul 11;16:442. doi: 10.1186/s12885-016-2524-6.


Molecular basis of differentiation therapy for soft tissue sarcomas.

Luther G, Rames R, Wagner ER, Zhu G, Luo Q, Bi Y, Kim SH, Gao JL, Huang E, Yang K, Wang L, Liu X, Li M, Hu N, Su Y, Luo X, Chen L, Luo J, Haydon RC, Luu HH, Zhou L, He TC.

Trends Cancer Res. 2010;6:69-90.


Cell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health.

Grootaert C, Kamiloglu S, Capanoglu E, Van Camp J.

Nutrients. 2015 Nov 11;7(11):9229-55. doi: 10.3390/nu7115462. Review.


Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells.

Aouali N, Broukou A, Bosseler M, Keunen O, Schlesser V, Janji B, Palissot V, Stordeur P, Berchem G.

PLoS One. 2015 Jun 19;10(6):e0130339. doi: 10.1371/journal.pone.0130339. eCollection 2015.


Chemotherapy and chemoprevention by thiazolidinediones.

Fröhlich E, Wahl R.

Biomed Res Int. 2015;2015:845340. doi: 10.1155/2015/845340. Epub 2015 Mar 19. Review.


Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect.

Beluzi M, Peres SB, Henriques FS, Sertié RA, Franco FO, Santos KB, Knobl P, Andreotti S, Shida CS, Neves RX, Farmer SR, Seelaender M, Lima FB, Batista ML Jr.

PLoS One. 2015 Mar 25;10(3):e0122660. doi: 10.1371/journal.pone.0122660. eCollection 2015.


Extensive lipoma-like changes of myxoid liposarcoma: morphologic, immunohistochemical, and molecular cytogenetic analyses.

Iwasaki H, Ishiguro M, Nishio J, Aoki M, Yokoyama R, Yokoyama K, Taguchi K, Nabeshima K.

Virchows Arch. 2015 Apr;466(4):453-64. doi: 10.1007/s00428-015-1721-z. Epub 2015 Feb 4.


Advances in the targeted therapy of liposarcoma.

Guan Z, Yu X, Wang H, Wang H, Zhang J, Li G, Cao J, Teng L.

Onco Targets Ther. 2015 Jan 5;8:125-36. doi: 10.2147/OTT.S72722. eCollection 2015. Review.


PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines.

Yoon YS, Kim SY, Kim MJ, Lim JH, Cho MS, Kang JL.

Mucosal Immunol. 2015 Sep;8(5):1031-46. doi: 10.1038/mi.2014.130. Epub 2015 Jan 14.


Pleiotropic role of PPARγ in intracerebral hemorrhage: an intricate system involving Nrf2, RXR, and NF-κB.

Zhao XR, Gonzales N, Aronowski J.

CNS Neurosci Ther. 2015 Apr;21(4):357-66. doi: 10.1111/cns.12350. Epub 2014 Nov 28. Review.


Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells.

Ninomiya I, Yamazaki K, Oyama K, Hayashi H, Tajima H, Kitagawa H, Fushida S, Fujimura T, Ohta T.

Oncol Lett. 2014 Dec;8(6):2709-2714. Epub 2014 Sep 23.


Pax-8-PPAR-γ fusion protein in thyroid carcinoma.

Raman P, Koenig RJ.

Nat Rev Endocrinol. 2014 Oct;10(10):616-23. doi: 10.1038/nrendo.2014.115. Epub 2014 Jul 29. Review.

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