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Items: 1 to 20 of 50

1.

Acute effects of ethanol on GABAA and glycine currents in the lateral habenula neurons of young rats.

Xie Z, Li G, Ye JH.

Open J Neurosci. 2013;3. pii: 5. doi: 10.13055/ojns_3_1_5.130821.

2.

Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.

Chen Q, Wells MM, Tillman TS, Kinde MN, Cohen A, Xu Y, Tang P.

Structure. 2017 Jan 3;25(1):180-187. doi: 10.1016/j.str.2016.11.007.

PMID:
27916519
3.

Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.

Burgos CF, Yévenes GE, Aguayo LG.

Mol Pharmacol. 2016 Sep;90(3):318-25. doi: 10.1124/mol.116.105726.

PMID:
27401877
4.

Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor.

McCracken ML, Gorini G, McCracken LM, Mayfield RD, Harris RA, Trudell JR.

Front Mol Neurosci. 2016 Jun 14;9:45. doi: 10.3389/fnmol.2016.00045.

5.

Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses.

Burgos CF, Muñoz B, Guzman L, Aguayo LG.

Pharmacol Res. 2015 Nov;101:18-29. doi: 10.1016/j.phrs.2015.07.002. Review.

6.

Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol.

Naito A, Muchhala KH, Trang J, Asatryan L, Trudell JR, Homanics GE, Alkana RL, Davies DL.

Neuroscience. 2015 Jun 25;297:68-77. doi: 10.1016/j.neuroscience.2015.03.034.

7.

Control of ethanol sensitivity of the glycine receptor α3 subunit by transmembrane 2, the intracellular splice cassette and C-terminal domains.

Sánchez A, Yévenes GE, San Martin L, Burgos CF, Moraga-Cid G, Harvey RJ, Aguayo LG.

J Pharmacol Exp Ther. 2015 Apr;353(1):80-90.

8.

Anesthetic diffusion through lipid membranes depends on the protonation rate.

Pérez-Isidoro R, Sierra-Valdez FJ, Ruiz-Suárez JC.

Sci Rep. 2014 Dec 18;4:7534. doi: 10.1038/srep07534.

9.

Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research.

Naito A, Muchhala KH, Asatryan L, Trudell JR, Homanics GE, Perkins DI, Davies DL, Alkana RL.

Mol Pharmacol. 2014 Dec;86(6):635-46. doi: 10.1124/mol.114.093773.

10.

Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats.

Li YL, Liu Q, Gong Q, Li JX, Wei SP, Wang YT, Liang H, Zhang M, Jing L, Yong Z, Lawrence AJ, Liang JH.

Acta Pharmacol Sin. 2014 Jul;35(7):853-61. doi: 10.1038/aps.2014.28.

11.

Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics.

Howard RJ, Trudell JR, Harris RA.

Pharmacol Rev. 2014 Feb 10;66(2):396-412. doi: 10.1124/pr.113.007468. Review.

12.

Glycine receptor mouse mutants: model systems for human hyperekplexia.

Schaefer N, Langlhofer G, Kluck CJ, Villmann C.

Br J Pharmacol. 2013 Nov;170(5):933-52. doi: 10.1111/bph.12335. Review.

13.

The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila.

Das J, Xu S, Pany S, Guillory A, Shah V, Roman GW.

J Neurochem. 2013 Sep;126(6):715-26. doi: 10.1111/jnc.12315.

14.

Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.

Sauguet L, Howard RJ, Malherbe L, Lee US, Corringer PJ, Harris RA, Delarue M.

Nat Commun. 2013;4:1697. doi: 10.1038/ncomms2682.

15.

Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).

Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price KL, Weston DA, Strelkov SV, Tytgat J, Bertrand S, Bertrand D, Lummis SC, Ulens C.

J Biol Chem. 2013 Mar 22;288(12):8355-64. doi: 10.1074/jbc.M112.424507.

16.

Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo.

McCracken LM, Blednov YA, Trudell JR, Benavidez JM, Betz H, Harris RA.

J Pharmacol Exp Ther. 2013 Feb;344(2):489-500. doi: 10.1124/jpet.112.197707.

17.

Molecular mechanism for the dual alcohol modulation of Cys-loop receptors.

Murail S, Howard RJ, Broemstrup T, Bertaccini EJ, Harris RA, Trudell JR, Lindahl E.

PLoS Comput Biol. 2012;8(10):e1002710. doi: 10.1371/journal.pcbi.1002710.

18.

Intoxicated Na(+) channels. Focus on "ethanol stimulates epithelial sodium channels by elevating reactive oxygen species".

Snyder PM.

Am J Physiol Cell Physiol. 2012 Dec 1;303(11):C1125-6. doi: 10.1152/ajpcell.00301.2012. No abstract available.

19.

Differential actions of isoflurane and ketamine-based anaesthetics on cochlear function in the mouse.

Cederholm JM, Froud KE, Wong AC, Ko M, Ryan AF, Housley GD.

Hear Res. 2012 Oct;292(1-2):71-9. doi: 10.1016/j.heares.2012.08.010.

20.

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice.

Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI 2nd, Harris RA.

Anesthesiology. 2012 Oct;117(4):765-71.

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