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Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes.

Sakakibara Y, Chow CS.

Org Biomol Chem. 2017 Oct 18;15(40):8535-8543. doi: 10.1039/c7ob02147j.


Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases.

Keeling KM.

Diseases. 2016 Dec;4(4). pii: 32. doi: 10.3390/diseases4040032. Epub 2016 Oct 19.


Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe.

Nuthanakanti A, Boerneke MA, Hermann T, Srivatsan SG.

Angew Chem Int Ed Engl. 2017 Mar 1;56(10):2640-2644. doi: 10.1002/anie.201611700. Epub 2017 Feb 3.


A recent intermezzo at the Ribosome Club.

Pavlov MY, Liljas A, Ehrenberg M.

Philos Trans R Soc Lond B Biol Sci. 2017 Mar 19;372(1716). pii: 20160185. doi: 10.1098/rstb.2016.0185. Review.


Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa.

Valencia EY, Esposito F, Spira B, Blázquez J, Galhardo RS.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02107-16. doi: 10.1128/AAC.02107-16. Print 2017 Mar.


PharmGKB summary: very important pharmacogene information for MT-RNR1.

Barbarino JM, McGregor TL, Altman RB, Klein TE.

Pharmacogenet Genomics. 2016 Dec;26(12):558-567. No abstract available.


Studies of RNA Sequence and Structure Using Nanopores.

Henley RY, Carson S, Wanunu M.

Prog Mol Biol Transl Sci. 2016;139:73-99. doi: 10.1016/bs.pmbts.2015.10.020. Review.


Bacterial GCN5-Related N-Acetyltransferases: From Resistance to Regulation.

Favrot L, Blanchard JS, Vergnolle O.

Biochemistry. 2016 Feb 23;55(7):989-1002. doi: 10.1021/acs.biochem.5b01269. Epub 2016 Feb 9. Review.


Geneticin Stabilizes the Open Conformation of the 5' Region of Hepatitis C Virus RNA and Inhibits Viral Replication.

Ariza-Mateos A, Díaz-Toledano R, Block TM, Prieto-Vega S, Birk A, Gómez J.

Antimicrob Agents Chemother. 2015 Nov 30;60(2):925-35. doi: 10.1128/AAC.02511-15. Print 2016 Feb.


Antibiotic drugs targeting bacterial RNAs.

Hong W, Zeng J, Xie J.

Acta Pharm Sin B. 2014 Aug;4(4):258-65. doi: 10.1016/j.apsb.2014.06.012. Epub 2014 Jul 31. Review.


Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy.

Rzuczek SG, Southern MR, Disney MD.

ACS Chem Biol. 2015 Dec 18;10(12):2706-15. doi: 10.1021/acschembio.5b00430. Epub 2015 Sep 28.


d-Methionine reduces tobramycin-induced ototoxicity without antimicrobial interference in animal models.

Fox DJ, Cooper MD, Speil CA, Roberts MH, Yanik SC, Meech RP, Hargrove TL, Verhulst SJ, Rybak LP, Campbell KC.

J Cyst Fibros. 2016 Jul;15(4):518-30. doi: 10.1016/j.jcf.2015.06.005. Epub 2015 Jul 10.


Mitochondrial ribosome assembly in health and disease.

De Silva D, Tu YT, Amunts A, Fontanesi F, Barrientos A.

Cell Cycle. 2015;14(14):2226-50. doi: 10.1080/15384101.2015.1053672. Epub 2015 Jun 1. Review.


Structural Insights into tRNA Dynamics on the Ribosome.

Agirrezabala X, Valle M.

Int J Mol Sci. 2015 Apr 30;16(5):9866-95. doi: 10.3390/ijms16059866. Review.


Integrating molecular dynamics simulations with chemical probing experiments using SHAPE-FIT.

Kirmizialtin S, Hennelly SP, Schug A, Onuchic JN, Sanbonmatsu KY.

Methods Enzymol. 2015;553:215-34. doi: 10.1016/bs.mie.2014.10.061. Epub 2015 Feb 7.


Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library.

Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP.

ACS Chem Biol. 2015 May 15;10(5):1278-89. doi: 10.1021/cb5010367. Epub 2015 Feb 23.


Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes.

Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL.

J Invest Dermatol. 2015 Jun;135(6):1581-1589. doi: 10.1038/jid.2015.40. Epub 2015 Feb 10.


RNA-seq analysis of the effect of kanamycin and the ABC transporter AtWBC19 on Arabidopsis thaliana seedlings reveals changes in metal content.

Mentewab A, Matheson K, Adebiyi M, Robinson S, Elston B.

PLoS One. 2014 Oct 13;9(10):e109310. doi: 10.1371/journal.pone.0109310. eCollection 2014.


Engineering persister-specific antibiotics with synergistic antimicrobial functions.

Schmidt NW, Deshayes S, Hawker S, Blacker A, Kasko AM, Wong GC.

ACS Nano. 2014 Sep 23;8(9):8786-93. doi: 10.1021/nn502201a. Epub 2014 Aug 18.


Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance.

Demirci H, Murphy FV 4th, Murphy EL, Connetti JL, Dahlberg AE, Jogl G, Gregory ST.

Antimicrob Agents Chemother. 2014 Aug;58(8):4308-17. doi: 10.1128/AAC.02857-14. Epub 2014 May 12.

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