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Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

Weems JC, Slaughter BD, Unruh JR, Boeing S, Hall SM, McLaird MB, Yasukawa T, Aso T, Svejstrup JQ, Conaway JW, Conaway RC.

J Biol Chem. 2017 Apr 21;292(16):6431-6437. doi: 10.1074/jbc.C117.777946. Epub 2017 Mar 14.


EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.

Liefke R, Karwacki-Neisius V, Shi Y.

Mol Cell. 2016 Nov 17;64(4):659-672. doi: 10.1016/j.molcel.2016.10.019.


Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses.

Weems JC, Slaughter BD, Unruh JR, Hall SM, McLaird MB, Gilmore JM, Washburn MP, Florens L, Yasukawa T, Aso T, Conaway JW, Conaway RC.

J Biol Chem. 2015 Jun 12;290(24):15030-41. doi: 10.1074/jbc.M114.632794. Epub 2015 Apr 15.


The elongin complex antagonizes the chromatin factor Corto for vein versus intervein cell identity in Drosophila wings.

Rougeot J, Renard M, Randsholt NB, Peronnet F, Mouchel-Vielh E.

PLoS One. 2013 Oct 21;8(10):e77592. doi: 10.1371/journal.pone.0077592. eCollection 2013.


Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins.

Nelson DE, Randle SJ, Laman H.

Open Biol. 2013 Oct 9;3(10):130131. doi: 10.1098/rsob.130131. Review.


Transcriptional properties of mammalian elongin A and its role in stress response.

Kawauchi J, Inoue M, Fukuda M, Uchida Y, Yasukawa T, Conaway RC, Conaway JW, Aso T, Kitajima S.

J Biol Chem. 2013 Aug 23;288(34):24302-15. doi: 10.1074/jbc.M113.496703. Epub 2013 Jul 3.


The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1.

Hu CZ, Sethi JK, Hagen T.

Biochem Res Int. 2012;2012:282648. doi: 10.1155/2012/282648. Epub 2012 Dec 9.


Efficient and rapid nucleosome traversal by RNA polymerase II depends on a combination of transcript elongation factors.

Luse DS, Spangler LC, Újvári A.

J Biol Chem. 2011 Feb 25;286(8):6040-8. doi: 10.1074/jbc.M110.174722. Epub 2010 Dec 22.


Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.

Yasukawa T, Kamura T, Kitajima S, Conaway RC, Conaway JW, Aso T.

EMBO J. 2008 Dec 17;27(24):3256-66. doi: 10.1038/emboj.2008.249. Epub 2008 Nov 27.


SOCS2 can enhance interleukin-2 (IL-2) and IL-3 signaling by accelerating SOCS3 degradation.

Tannahill GM, Elliott J, Barry AC, Hibbert L, Cacalano NA, Johnston JA.

Mol Cell Biol. 2005 Oct;25(20):9115-26.


VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.

Genes Dev. 2004 Dec 15;18(24):3055-65.


In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development.

Gerber M, Eissenberg JC, Kong S, Tenney K, Conaway JW, Conaway RC, Shilatifard A.

Mol Cell Biol. 2004 Nov;24(22):9911-9.


Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.

Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. Epub 2002 Jul 29.


CUL-4A is critical for early embryonic development.

Li B, Ruiz JC, Chun KT.

Mol Cell Biol. 2002 Jul;22(14):4997-5005.


Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.

Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D, Kaelin WG, Conaway RC, Conaway JW, Branton PE.

Genes Dev. 2001 Dec 1;15(23):3104-17.


The F-box protein family.

Kipreos ET, Pagano M.

Genome Biol. 2000;1(5):REVIEWS3002. Epub 2000 Nov 10. Review.


SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Willems AR, Goh T, Taylor L, Chernushevich I, Shevchenko A, Tyers M.

Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1533-50.


Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C.

Botuyan MV, Koth CM, Mer G, Chakrabartty A, Conaway JW, Conaway RC, Edwards AM, Arrowsmith CH, Chazin WJ.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9033-8.

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