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Items: 1 to 20 of 147


CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus.

Gorter de Vries AR, de Groot PA, van den Broek M, Daran JG.

Microb Cell Fact. 2017 Dec 5;16(1):222. doi: 10.1186/s12934-017-0835-1.


Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.

Schimmel J, Kool H, van Schendel R, Tijsterman M.

EMBO J. 2017 Dec 15;36(24):3634-3649. doi: 10.15252/embj.201796948. Epub 2017 Oct 27.


Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction.

Guintini L, Tremblay M, Toussaint M, D'Amours A, Wellinger RE, Wellinger RJ, Conconi A.

Nucleic Acids Res. 2017 May 5;45(8):4577-4589. doi: 10.1093/nar/gkx123.


Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.

Li Y, Wang J, Zhou G, Lajeunesse M, Le N, Stawicki BN, Corcino YL, Berkner KL, Runge KW.

Genetics. 2017 May;206(1):481-496. doi: 10.1534/genetics.117.200972. Epub 2017 Mar 14.


Microhomology-mediated end joining: new players join the team.

Wang H, Xu X.

Cell Biosci. 2017 Jan 13;7:6. doi: 10.1186/s13578-017-0136-8. eCollection 2017. Review.


Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions.

Konomura N, Arai N, Shinohara T, Kobayashi J, Iwasaki W, Ikawa S, Kusano K, Shibata T.

Nucleic Acids Res. 2017 Jan 9;45(1):337-352. doi: 10.1093/nar/gkw998. Epub 2016 Oct 27.


DNA Polymerase θ: A Unique Multifunctional End-Joining Machine.

Black SJ, Kashkina E, Kent T, Pomerantz RT.

Genes (Basel). 2016 Sep 21;7(9). pii: E67. doi: 10.3390/genes7090067. Review.


Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.

Wyatt DW, Feng W, Conlin MP, Yousefzadeh MJ, Roberts SA, Mieczkowski P, Wood RD, Gupta GP, Ramsden DA.

Mol Cell. 2016 Aug 18;63(4):662-673. doi: 10.1016/j.molcel.2016.06.020. Epub 2016 Jul 21.


The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.

Jasin M, Haber JE.

DNA Repair (Amst). 2016 Aug;44:6-16. doi: 10.1016/j.dnarep.2016.05.001. Epub 2016 May 12. Review.


Consider the workhorse: Nonhomologous end-joining in budding yeast.

Emerson CH, Bertuch AA.

Biochem Cell Biol. 2016 Oct;94(5):396-406. Epub 2016 Mar 31. Review.


Noncanonical views of homology-directed DNA repair.

Verma P, Greenberg RA.

Genes Dev. 2016 May 15;30(10):1138-54. doi: 10.1101/gad.280545.116. Review.


A role for human homologous recombination factors in suppressing microhomology-mediated end joining.

Ahrabi S, Sarkar S, Pfister SX, Pirovano G, Higgins GS, Porter AC, Humphrey TC.

Nucleic Acids Res. 2016 Jul 8;44(12):5743-57. doi: 10.1093/nar/gkw326. Epub 2016 Apr 29.


Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?

Tsai RY.

Cell Mol Life Sci. 2016 May;73(9):1803-23. doi: 10.1007/s00018-016-2152-y. Epub 2016 Feb 17. Review.


Risky business: Microhomology-mediated end joining.

Sinha S, Villarreal D, Shim EY, Lee SE.

Mutat Res. 2016 Jun;788:17-24. doi: 10.1016/j.mrfmmm.2015.12.005. Epub 2016 Jan 2. Review.


Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions.

Tadi SK, Sebastian R, Dahal S, Babu RK, Choudhary B, Raghavan SC.

Mol Biol Cell. 2016 Jan 15;27(2):223-35. doi: 10.1091/mbc.E15-05-0260. Epub 2015 Nov 25.


Linking replication stress with heterochromatin formation.

Nikolov I, Taddei A.

Chromosoma. 2016 Jun;125(3):523-33. doi: 10.1007/s00412-015-0545-6. Epub 2015 Oct 28. Review.


Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer.

Konstantinopoulos PA, Ceccaldi R, Shapiro GI, D'Andrea AD.

Cancer Discov. 2015 Nov;5(11):1137-54. doi: 10.1158/2159-8290.CD-15-0714. Epub 2015 Oct 13. Review.


Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

Sfeir A, Symington LS.

Trends Biochem Sci. 2015 Nov;40(11):701-714. doi: 10.1016/j.tibs.2015.08.006. Epub 2015 Oct 1. Review.


BRCA1 Mutation: A Predictive Marker for Radiation Therapy?

Kan C, Zhang J.

Int J Radiat Oncol Biol Phys. 2015 Oct 1;93(2):281-93. doi: 10.1016/j.ijrobp.2015.05.037. Review.


Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.

Galli A, Chan CY, Parfenova L, Cervelli T, Schiestl RH.

Mutagenesis. 2015 Nov;30(6):841-9. doi: 10.1093/mutage/gev046. Epub 2015 Jun 29.

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