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Items: 1 to 20 of 38

1.

The Role of Integrins αMβ2 (Mac-1, CD11b/CD18) and αDβ2 (CD11d/CD18) in Macrophage Fusion.

Podolnikova NP, Kushchayeva YS, Wu Y, Faust J, Ugarova TP.

Am J Pathol. 2016 Aug;186(8):2105-2116. doi: 10.1016/j.ajpath.2016.04.001. Epub 2016 Jun 14.

2.

Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease.

Mitroulis I, Alexaki VI, Kourtzelis I, Ziogas A, Hajishengallis G, Chavakis T.

Pharmacol Ther. 2015 Mar;147:123-135. doi: 10.1016/j.pharmthera.2014.11.008. Epub 2014 Nov 14. Review.

3.

Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts.

Grove LM, Southern BD, Jin TH, White KE, Paruchuri S, Harel E, Wei Y, Rahaman SO, Gladson CL, Ding Q, Craik CS, Chapman HA, Olman MA.

J Biol Chem. 2014 May 2;289(18):12791-804. doi: 10.1074/jbc.M113.498576. Epub 2014 Mar 18.

4.

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM.

Maiti AK, Kim-Howard X, Motghare P, Pradhan V, Chua KH, Sun C, Arango-Guerrero MT, Ghosh K, Niewold TB, Harley JB, Anaya JM, Looger LL, Nath SK.

Hum Mol Genet. 2014 Aug 1;23(15):4161-76. doi: 10.1093/hmg/ddu106. Epub 2014 Mar 7.

5.

Role of urokinase receptor in tumor progression and development.

Noh H, Hong S, Huang S.

Theranostics. 2013 Jun 25;3(7):487-95. doi: 10.7150/thno.4218. Print 2013. Review.

6.

Plasminogen receptors: the first quarter century.

Miles LA, Parmer RJ.

Semin Thromb Hemost. 2013 Jun;39(4):329-37. doi: 10.1055/s-0033-1334483. Epub 2013 Mar 26. Review.

7.

Potential role of kringle-integrin interaction in plasmin and uPA actions (a hypothesis).

Takada Y.

J Biomed Biotechnol. 2012;2012:136302. doi: 10.1155/2012/136302. Epub 2012 Oct 16.

8.

VEGF-initiated angiogenesis and the uPA/uPAR system.

Breuss JM, Uhrin P.

Cell Adh Migr. 2012 Nov-Dec;6(6):535-615. doi: 10.4161/cam.22243. Epub 2012 Oct 17. Review.

9.

Fibrinogen counteracts the antiadhesive effect of fibrin-bound plasminogen by preventing its activation by adherent U937 monocytic cells.

Lishko VK, Yermolenko IS, Owaynat H, Ugarova TP.

J Thromb Haemost. 2012 Jun;10(6):1081-90. doi: 10.1111/j.1538-7836.2012.04745.x.

10.

Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.

Graziano F, Elia C, Laudanna C, Poli G, Alfano M.

PLoS One. 2011;6(8):e23674. doi: 10.1371/journal.pone.0023674. Epub 2011 Aug 17.

11.

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.

Tieu BC, Lee C, Sun H, Lejeune W, Recinos A 3rd, Ju X, Spratt H, Guo DC, Milewicz D, Tilton RG, Brasier AR.

J Clin Invest. 2009 Dec;119(12):3637-51. doi: 10.1172/JCI38308. Epub 2009 Nov 16.

12.

Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.

Zhu S, Gladson CL, White KE, Ding Q, Stewart J Jr, Jin TH, Chapman HA Jr, Olman MA.

Am J Physiol Lung Cell Mol Physiol. 2009 Jul;297(1):L97-108. doi: 10.1152/ajplung.90283.2008. Epub 2009 May 1.

13.

Signaling through urokinase and urokinase receptor in lung cancer cells requires interactions with beta1 integrins.

Tang CH, Hill ML, Brumwell AN, Chapman HA, Wei Y.

J Cell Sci. 2008 Nov 15;121(Pt 22):3747-56. doi: 10.1242/jcs.029769. Epub 2008 Oct 21.

14.

uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.

Smith HW, Marra P, Marshall CJ.

J Cell Biol. 2008 Aug 25;182(4):777-90. doi: 10.1083/jcb.200712050.

15.

Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection.

Shimizu K, Libby P, Shubiki R, Sakuma M, Wang Y, Asano K, Mitchell RN, Simon DI.

Circulation. 2008 Apr 15;117(15):1997-2008. doi: 10.1161/CIRCULATIONAHA.107.724310. Epub 2008 Mar 31.

16.

The Pseudomonas aeruginosa LasB metalloproteinase regulates the human urokinase-type plasminogen activator receptor through domain-specific endoproteolysis.

Leduc D, Beaufort N, de Bentzmann S, Rousselle JC, Namane A, Chignard M, Pidard D.

Infect Immun. 2007 Aug;75(8):3848-58. Epub 2007 May 21.

17.

Structural basis of interaction between urokinase-type plasminogen activator and its receptor.

Barinka C, Parry G, Callahan J, Shaw DE, Kuo A, Bdeir K, Cines DB, Mazar A, Lubkowski J.

J Mol Biol. 2006 Oct 20;363(2):482-95. Epub 2006 Aug 26.

18.

High-molecular-weight kininogen fragments stimulate the secretion of cytokines and chemokines through uPAR, Mac-1, and gC1qR in monocytes.

Khan MM, Bradford HN, Isordia-Salas I, Liu Y, Wu Y, Espinola RG, Ghebrehiwet B, Colman RW.

Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2260-6. Epub 2006 Aug 10. Erratum in: Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):e146.

19.

Science review: searching for gene candidates in acute lung injury.

Grigoryev DN, Finigan JH, Hassoun P, Garcia JG.

Crit Care. 2004 Dec;8(6):440-7. Epub 2004 Jun 30. Review.

20.

Targeting platelet-leukocyte interactions: identification of the integrin Mac-1 binding site for the platelet counter receptor glycoprotein Ibalpha.

Ehlers R, Ustinov V, Chen Z, Zhang X, Rao R, Luscinskas FW, Lopez J, Plow E, Simon DI.

J Exp Med. 2003 Oct 6;198(7):1077-88.

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