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Items: 1 to 20 of 87

1.

Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia.

Kesarwani M, Kincaid Z, Gomaa A, Huber E, Rohrabaugh S, Siddiqui Z, Bouso MF, Latif T, Xu M, Komurov K, Mulloy JC, Cancelas JA, Grimes HL, Azam M.

Nat Med. 2017 Apr;23(4):472-482. doi: 10.1038/nm.4310. Epub 2017 Mar 20.

PMID:
28319094
3.

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.

Kidger AM, Rushworth LK, Stellzig J, Davidson J, Bryant CJ, Bayley C, Caddye E, Rogers T, Keyse SM, Caunt CJ.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E317-E326. doi: 10.1073/pnas.1614684114. Epub 2017 Jan 4.

4.

MicroRNAs in the thyroid.

Boufraqech M, Klubo-Gwiezdzinska J, Kebebew E.

Best Pract Res Clin Endocrinol Metab. 2016 Oct;30(5):603-619. doi: 10.1016/j.beem.2016.10.001. Epub 2016 Nov 1. Review.

PMID:
27923454
5.
6.

Long-term dynamics of multisite phosphorylation.

Rubinstein BY, Mattingly HH, Berezhkovskii AM, Shvartsman SY.

Mol Biol Cell. 2016 Jul 15;27(14):2331-40. doi: 10.1091/mbc.E16-03-0137. Epub 2016 May 25.

7.

The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs).

Kidger AM, Keyse SM.

Semin Cell Dev Biol. 2016 Feb;50:125-32. doi: 10.1016/j.semcdb.2016.01.009. Epub 2016 Jan 11. Review.

8.

Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription Factor.

Buffet C, Catelli MG, Hecale-Perlemoine K, Bricaire L, Garcia C, Gallet-Dierick A, Rodriguez S, Cormier F, Groussin L.

PLoS One. 2015 Dec 21;10(12):e0145484. doi: 10.1371/journal.pone.0145484. eCollection 2015.

9.

MAPK phosphatase 7 regulates T cell differentiation via inhibiting ERK-mediated IL-2 expression.

Zhang Y, Nallaparaju KC, Liu X, Jiao H, Reynolds JM, Wang ZX, Dong C.

J Immunol. 2015 Apr 1;194(7):3088-95. doi: 10.4049/jimmunol.1402638. Epub 2015 Feb 25.

10.

Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling.

Wales S, Hashemi S, Blais A, McDermott JC.

Nucleic Acids Res. 2014 Oct;42(18):11349-62. doi: 10.1093/nar/gku813. Epub 2014 Sep 12.

11.

BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization.

Orvis T, Hepperla A, Walter V, Song S, Simon J, Parker J, Wilkerson MD, Desai N, Major MB, Hayes DN, Davis IJ, Weissman B.

Cancer Res. 2014 Nov 15;74(22):6486-98. doi: 10.1158/0008-5472.CAN-14-0061. Epub 2014 Aug 12.

12.

In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase.

Korotchenko VN, Saydmohammed M, Vollmer LL, Bakan A, Sheetz K, Debiec KT, Greene KA, Agliori CS, Bahar I, Day BW, Vogt A, Tsang M.

Chembiochem. 2014 Jul 7;15(10):1436-45. doi: 10.1002/cbic.201402000. Epub 2014 Jun 6.

14.

The mechanism by which MEK/ERK regulates JNK and p38 activity in polyamine depleted IEC-6 cells during apoptosis.

Bavaria MN, Jin S, Ray RM, Johnson LR.

Apoptosis. 2014 Mar;19(3):467-79. doi: 10.1007/s10495-013-0944-1.

15.

Identification of estrogen target genes during zebrafish embryonic development through transcriptomic analysis.

Hao R, Bondesson M, Singh AV, Riu A, McCollum CW, Knudsen TB, Gorelick DA, Gustafsson JÅ.

PLoS One. 2013 Nov 6;8(11):e79020. doi: 10.1371/journal.pone.0079020. eCollection 2013.

16.

MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition.

Taylor DM, Moser R, Régulier E, Breuillaud L, Dixon M, Beesen AA, Elliston L, Silva Santos Mde F, Kim J, Jones L, Goldstein DR, Ferrante RJ, Luthi-Carter R.

J Neurosci. 2013 Feb 6;33(6):2313-25. doi: 10.1523/JNEUROSCI.4965-11.2013.

17.

An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation.

Aijö T, Edelman SM, Lönnberg T, Larjo A, Kallionpää H, Tuomela S, Engström E, Lahesmaa R, Lähdesmäki H.

BMC Genomics. 2012 Oct 30;13:572. doi: 10.1186/1471-2164-13-572.

18.
19.

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.

Caunt CJ, Keyse SM.

FEBS J. 2013 Jan;280(2):489-504. doi: 10.1111/j.1742-4658.2012.08716.x. Epub 2012 Aug 28. Review.

20.

MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells.

Feng B, Jiao P, Yang Z, Xu H.

Mol Cell Endocrinol. 2012 Sep 25;361(1-2):116-23. doi: 10.1016/j.mce.2012.03.025. Epub 2012 Apr 12.

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