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Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells.

Guha G, Lu W, Li S, Liang X, Kulesz-Martin MF, Mahmud T, Indra AK, Ganguli-Indra G.

PLoS One. 2015 May 4;10(5):e0125322. doi: 10.1371/journal.pone.0125322. eCollection 2015.


C/EBPα regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint.

Hall JR, Bereman MS, Nepomuceno AI, Thompson EA, Muddiman DC, Smart RC.

Cell Cycle. 2014;13(22):3602-10. doi: 10.4161/15384101.2014.962957.


Combinatorial measurement of CDKN1A/p21 and KIF20A expression for discrimination of DNA damage-induced clastogenicity.

Sakai R, Morikawa Y, Kondo C, Oka H, Miyajima H, Kubo K, Uehara T.

Int J Mol Sci. 2014 Sep 26;15(10):17256-69. doi: 10.3390/ijms151017256.


Chimeras of p14ARF and p16: functional hybrids with the ability to arrest growth.

Williams RT, Barnhill LM, Kuo HH, Lin WD, Batova A, Yu AL, Diccianni MB.

PLoS One. 2014 Feb 5;9(2):e88219. doi: 10.1371/journal.pone.0088219. eCollection 2014.


Histone deacetylase inhibition with valproic acid downregulates osteocalcin gene expression in human dental pulp stem cells and osteoblasts: evidence for HDAC2 involvement.

Paino F, La Noce M, Tirino V, Naddeo P, Desiderio V, Pirozzi G, De Rosa A, Laino L, Altucci L, Papaccio G.

Stem Cells. 2014 Jan;32(1):279-89. doi: 10.1002/stem.1544.


Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.

Zhao H, Chen X, Gurian-West M, Roberts JM.

Mol Cell Biol. 2012 Apr;32(8):1421-32. doi: 10.1128/MCB.06721-11. Epub 2012 Feb 13.


Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry.

Enders GH.

Cell Div. 2010 May 13;5:12. doi: 10.1186/1747-1028-5-12.


Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect.

Wang X, Allen TD, May RJ, Lightfoot S, Houchen CW, Huycke MM.

Cancer Res. 2008 Dec 1;68(23):9909-17. doi: 10.1158/0008-5472.CAN-08-1551.


Nuclear HuR accumulation through phosphorylation by Cdk1.

Kim HH, Abdelmohsen K, Lal A, Pullmann R Jr, Yang X, Galban S, Srikantan S, Martindale JL, Blethrow J, Shokat KM, Gorospe M.

Genes Dev. 2008 Jul 1;22(13):1804-15. doi: 10.1101/gad.1645808.


Effect of nitric oxide donor and gamma irradiation on modifications of ERK and JNK in murine peritoneal macrophages.

Narang H, Dhariwala FA, Krishna M.

J Cell Commun Signal. 2007 Dec;1(3-4):219-26. doi: 10.1007/s12079-008-0021-7. Epub 2008 Jun 4.


Targeting NF-kappaB in Waldenstrom macroglobulinemia.

Leleu X, Eeckhoute J, Jia X, Roccaro AM, Moreau AS, Farag M, Sacco A, Ngo HT, Runnels J, Melhem MR, Burwick N, Azab A, Azab F, Hunter Z, Hatjiharissi E, Carrasco DR, Treon SP, Witzig TE, Hideshima T, Brown M, Anderson KC, Ghobrial IM.

Blood. 2008 May 15;111(10):5068-77. doi: 10.1182/blood-2007-09-115170. Epub 2008 Mar 11.


p21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.

Satyanarayana A, Hilton MB, Kaldis P.

Mol Biol Cell. 2008 Jan;19(1):65-77. Epub 2007 Oct 17.


Glycogen synthase kinase 3beta phosphorylates p21WAF1/CIP1 for proteasomal degradation after UV irradiation.

Lee JY, Yu SJ, Park YG, Kim J, Sohn J.

Mol Cell Biol. 2007 Apr;27(8):3187-98. Epub 2007 Feb 5.


The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light.

Al-Mohanna MA, Al-Khalaf HH, Al-Yousef N, Aboussekhra A.

Nucleic Acids Res. 2007;35(1):223-33. Epub 2006 Dec 7.


Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.

Fiedler N, Quant E, Fink L, Sun J, Schuster R, Gerlich WH, Schaefer S.

World J Gastroenterol. 2006 Aug 7;12(29):4673-82.


Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint.

Pedraza-Alva G, Koulnis M, Charland C, Thornton T, Clements JL, Schlissel MS, Rincón M.

EMBO J. 2006 Feb 22;25(4):763-73. Epub 2006 Feb 2.


DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.

Mol Biol Cell. 2003 Oct;14(10):3989-4002. Epub 2003 Jul 25.


Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.

Chattopadhyay D, Ghosh MK, Mal A, Harter ML.

J Virol. 2001 Oct;75(20):9844-56.

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