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Items: 20


Targeting ATM-deficient CLL through interference with DNA repair pathways.

Knittel G, Liedgens P, Reinhardt HC.

Front Genet. 2015 Jun 10;6:207. doi: 10.3389/fgene.2015.00207. eCollection 2015. Review.


DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.

Ashley AK, Shrivastav M, Nie J, Amerin C, Troksa K, Glanzer JG, Liu S, Opiyo SO, Dimitrova DD, Le P, Sishc B, Bailey SM, Oakley GG, Nickoloff JA.

DNA Repair (Amst). 2014 Sep;21:131-9. doi: 10.1016/j.dnarep.2014.04.008. Epub 2014 May 10.


Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase.

Köcher S, Rieckmann T, Rohaly G, Mansour WY, Dikomey E, Dornreiter I, Dahm-Daphi J.

Nucleic Acids Res. 2012 Sep 1;40(17):8336-47. Epub 2012 Jun 22.


ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.

Sirbu BM, Lachmayer SJ, Wülfing V, Marten LM, Clarkson KE, Lee LW, Gheorghiu L, Zou L, Powell SN, Dahm-Daphi J, Willers H.

PLoS One. 2011;6(8):e23053. doi: 10.1371/journal.pone.0023053. Epub 2011 Aug 12.


Exploiting synthetic lethal interactions for targeted cancer therapy.

Reinhardt HC, Jiang H, Hemann MT, Yaffe MB.

Cell Cycle. 2009 Oct 1;8(19):3112-9. Review.


DNA-PKcs and ATM co-regulate DNA double-strand break repair.

Shrivastav M, Miller CA, De Haro LP, Durant ST, Chen BP, Chen DJ, Nickoloff JA.

DNA Repair (Amst). 2009 Aug 6;8(8):920-9. doi: 10.1016/j.dnarep.2009.05.006. Epub 2009 Jun 16.


Tissue-specific differences in the accumulation of sequence rearrangements with age.

Wiktor-Brown DM, Olipitz W, Hendricks CA, Rugo RE, Engelward BP.

DNA Repair (Amst). 2008 May 3;7(5):694-703. doi: 10.1016/j.dnarep.2008.01.012. Epub 2008 Mar 20.


Repair of radiation damage to DNA.

Willers H, Dahm-Daphi J, Powell SN.

Br J Cancer. 2004 Apr 5;90(7):1297-301. Review.


Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F.

Mol Cell Biol. 2004 Jan;24(2):708-18.


Vanillins--a novel family of DNA-PK inhibitors.

Durant S, Karran P.

Nucleic Acids Res. 2003 Oct 1;31(19):5501-12.


Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias.

Starczynski J, Simmons W, Flavell JR, Byrd PJ, Stewart GS, Kullar HS, Groom A, Crocker J, Moss PA, Reynolds GM, Glavina-Durdov M, Taylor AM, Fegan C, Stankovic T, Murray PG.

Am J Pathol. 2003 Aug;163(2):423-32.


Homologous Recombination and Its Role in Carcinogenesis.

Bishop AJ, Schiestl RH.

J Biomed Biotechnol. 2002;2(2):75-85.


Replication protein A is sequentially phosphorylated during meiosis.

Brush GS, Clifford DM, Marinco SM, Bartrand AJ.

Nucleic Acids Res. 2001 Dec 1;29(23):4808-17.


Manipulating the mammalian genome by homologous recombination.

Vasquez KM, Marburger K, Intody Z, Wilson JH.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8403-10. Review.


Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining.

Xia F, Taghian DG, DeFrank JS, Zeng ZC, Willers H, Iliakis G, Powell SN.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8644-9. Epub 2001 Jul 10.


The controlling role of ATM in homologous recombinational repair of DNA damage.

Morrison C, Sonoda E, Takao N, Shinohara A, Yamamoto K, Takeda S.

EMBO J. 2000 Feb 1;19(3):463-71. Erratum in: EMBO J 2000 Feb 15;19(4):786.

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