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Blocking the Nav1.8 channel in the left stellate ganglion suppresses ventricular arrhythmia induced by acute ischemia in a canine model.

Yu L, Wang M, Hu D, Huang B, Zhou L, Zhou X, Wang Z, Wang S, Jiang H.

Sci Rep. 2017 Apr 3;7(1):534. doi: 10.1038/s41598-017-00642-6.


Use dependence of peripheral nociceptive conduction in the absence of tetrodotoxin-resistant sodium channel subtypes.

Hoffmann T, Kistner K, Nassar M, Reeh PW, Weidner C.

J Physiol. 2016 Oct 1;594(19):5529-41. doi: 10.1113/JP272082. Epub 2016 Jun 12.


Sodium channel diversity in the vestibular ganglion: NaV1.5, NaV1.8, and tetrodotoxin-sensitive currents.

Liu XP, Wooltorton JR, Gaboyard-Niay S, Yang FC, Lysakowski A, Eatock RA.

J Neurophysiol. 2016 May 1;115(5):2536-55. doi: 10.1152/jn.00902.2015. Epub 2016 Mar 2.


Primary erythromelalgia: a review.

Tang Z, Chen Z, Tang B, Jiang H.

Orphanet J Rare Dis. 2015 Sep 30;10:127. doi: 10.1186/s13023-015-0347-1. Review.


Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons.

Han C, Estacion M, Huang J, Vasylyev D, Zhao P, Dib-Hajj SD, Waxman SG.

J Neurophysiol. 2015 May 1;113(9):3172-85. doi: 10.1152/jn.00113.2015. Epub 2015 Mar 18.


Saltatory conduction in unmyelinated axons: clustering of Na(+) channels on lipid rafts enables micro-saltatory conduction in C-fibers.

Neishabouri A, Faisal AA.

Front Neuroanat. 2014 Oct 13;8:109. doi: 10.3389/fnana.2014.00109. eCollection 2014.


Alteration of the mu opioid receptor: Ca2+ channel signaling pathway in a subset of rat sensory neurons following chronic femoral artery occlusion.

Hassan B, Kim JS, Farrag M, Kaufman MP, Ruiz-Velasco V.

J Neurophysiol. 2014 Dec 15;112(12):3104-15. doi: 10.1152/jn.00630.2014. Epub 2014 Sep 17.


Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

Hu D, Barajas-Martínez H, Pfeiffer R, Dezi F, Pfeiffer J, Buch T, Betzenhauser MJ, Belardinelli L, Kahlig KM, Rajamani S, DeAntonio HJ, Myerburg RJ, Ito H, Deshmukh P, Marieb M, Nam GB, Bhatia A, Hasdemir C, Haïssaguerre M, Veltmann C, Schimpf R, Borggrefe M, Viskin S, Antzelevitch C.

J Am Coll Cardiol. 2014 Jul 8;64(1):66-79. doi: 10.1016/j.jacc.2014.04.032.


The κ-opioid receptor agonist U-50488 blocks Ca2+ channels in a voltage- and G protein-independent manner in sensory neurons.

Hassan B, Ruiz-Velasco V.

Reg Anesth Pain Med. 2013 Jan-Feb;38(1):21-7. doi: 10.1097/AAP.0b013e318274a8a1.


Gain-of-function Nav1.8 mutations in painful neuropathy.

Faber CG, Lauria G, Merkies IS, Cheng X, Han C, Ahn HS, Persson AK, Hoeijmakers JG, Gerrits MM, Pierro T, Lombardi R, Kapetis D, Dib-Hajj SD, Waxman SG.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19444-9. doi: 10.1073/pnas.1216080109. Epub 2012 Oct 31.


Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons.

Ho C, Zhao J, Malinowski S, Chahine M, O'Leary ME.

J Biol Chem. 2012 Apr 27;287(18):15044-53. doi: 10.1074/jbc.M111.333740. Epub 2012 Mar 9.


Regulatory Role of Voltage-Gated Na Channel β Subunits in Sensory Neurons.

Chahine M, O'Leary ME.

Front Pharmacol. 2011 Nov 21;2:70. doi: 10.3389/fphar.2011.00070. eCollection 2011.


Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.

Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19413-8. doi: 10.1073/pnas.1117020108. Epub 2011 Nov 15.


Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes.

Theile JW, Cummins TR.

Front Pharmacol. 2011 Oct 4;2:54. doi: 10.3389/fphar.2011.00054. eCollection 2011.


Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation.

Lolignier S, Amsalem M, Maingret F, Padilla F, Gabriac M, Chapuy E, Eschalier A, Delmas P, Busserolles J.

PLoS One. 2011;6(8):e23083. doi: 10.1371/journal.pone.0023083. Epub 2011 Aug 12.


Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits.

Zhao J, O'Leary ME, Chahine M.

J Neurophysiol. 2011 Aug;106(2):608-19. doi: 10.1152/jn.00107.2011. Epub 2011 May 11.


Na+ channel Scn1b gene regulates dorsal root ganglion nociceptor excitability in vivo.

Lopez-Santiago LF, Brackenbury WJ, Chen C, Isom LL.

J Biol Chem. 2011 Jul 1;286(26):22913-23. doi: 10.1074/jbc.M111.242370. Epub 2011 May 9.


A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain.

Lagerström MC, Rogoz K, Abrahamsen B, Lind AL, Olund C, Smith C, Mendez JA, Wallén-Mackenzie Å, Wood JN, Kullander K.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5789-94. doi: 10.1073/pnas.1013602108. Epub 2011 Mar 17.


Single-cell analysis of sodium channel expression in dorsal root ganglion neurons.

Ho C, O'Leary ME.

Mol Cell Neurosci. 2011 Jan;46(1):159-66. doi: 10.1016/j.mcn.2010.08.017. Epub 2010 Sep 9.


Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat.

Joseph EK, Levine JD.

Neuroscience. 2010 Nov 24;171(1):344-50. doi: 10.1016/j.neuroscience.2010.08.035. Epub 2010 Aug 22.

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