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Items: 1 to 20 of 83

1.

Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo.

van Dijk R, Aronson SJ, de Waart DR, van de Graaf SF, Duijst S, Seppen J, Elferink RO, Beuers U, Bosma PJ.

Sci Rep. 2017 May 10;7(1):1646. doi: 10.1038/s41598-017-01602-w.

2.

Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance.

Bekele RT, Venkatraman G, Liu RZ, Tang X, Mi S, Benesch MG, Mackey JR, Godbout R, Curtis JM, McMullen TP, Brindley DN.

Sci Rep. 2016 Feb 17;6:21164. doi: 10.1038/srep21164.

3.

Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis.

Chai J, Cai SY, Liu X, Lian W, Chen S, Zhang L, Feng X, Cheng Y, He X, He Y, Chen L, Wang R, Wang H, Boyer JL, Chen W.

J Hepatol. 2015 Dec;63(6):1440-8. doi: 10.1016/j.jhep.2015.07.016. Epub 2015 Jul 23.

4.

Structural and functional hepatocyte polarity and liver disease.

Gissen P, Arias IM.

J Hepatol. 2015 Oct;63(4):1023-37. doi: 10.1016/j.jhep.2015.06.015. Epub 2015 Jun 24. Review.

5.

Physiological and molecular biochemical mechanisms of bile formation.

Reshetnyak VI.

World J Gastroenterol. 2013 Nov 14;19(42):7341-60. doi: 10.3748/wjg.v19.i42.7341. Review.

6.

Polymers influencing transportability profile of drug.

Gaikwad VL, Bhatia MS.

Saudi Pharm J. 2013 Oct;21(4):327-35. doi: 10.1016/j.jsps.2012.10.003. Review.

7.

New insights in bilirubin metabolism and their clinical implications.

Sticova E, Jirsa M.

World J Gastroenterol. 2013 Oct 14;19(38):6398-407. doi: 10.3748/wjg.v19.i38.6398. Review.

8.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG.

Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Review.

9.

Selenoneine, a novel selenium-containing compound, mediates detoxification mechanisms against methylmercury accumulation and toxicity in zebrafish embryo.

Yamashita M, Yamashita Y, Suzuki T, Kani Y, Mizusawa N, Imamura S, Takemoto K, Hara T, Hossain MA, Yabu T, Touhata K.

Mar Biotechnol (NY). 2013 Oct;15(5):559-70. doi: 10.1007/s10126-013-9508-1. Epub 2013 May 25.

10.

Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition.

Ulloa JL, Stahl S, Yates J, Woodhouse N, Kenna JG, Jones HB, Waterton JC, Hockings PD.

NMR Biomed. 2013 Oct;26(10):1258-70. doi: 10.1002/nbm.2946. Epub 2013 Apr 7.

11.

An In Silico Classification Model for Putative ABCC2 Substrates.

Pinto M, Trauner M, Ecker GF.

Mol Inform. 2012 Aug;31(8):547-553. Epub 2012 Aug 9. No abstract available.

12.

Placental and fetal disposition of mercuric ions in rats exposed to methylmercury: role of Mrp2.

Bridges CC, Joshee L, Zalups RK.

Reprod Toxicol. 2012 Dec;34(4):628-34. doi: 10.1016/j.reprotox.2012.10.001. Epub 2012 Oct 8.

13.

A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.

Pramanik D, Campbell NR, Das S, Gupta S, Chenna V, Bisht S, Sysa-Shah P, Bedja D, Karikari C, Steenbergen C, Gabrielson KL, Maitra A, Maitra A.

Oncotarget. 2012 Jun;3(6):640-50.

14.

LOSS of Mrp1 alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner.

Sivils JC, Ancrum TM, Bain LJ.

J Appl Toxicol. 2013 Aug;33(8):766-73. doi: 10.1002/jat.2727. Epub 2012 Apr 23.

15.

Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene.

Villanueva SS, Perdomo VG, Ruiz ML, Rigalli JP, Arias A, Luquita MG, Vore M, Catania VA, Mottino AD.

Drug Metab Dispos. 2012 Jul;40(7):1252-8. doi: 10.1124/dmd.111.044339. Epub 2012 Mar 27.

16.

ABC transporters and their role in nucleoside and nucleotide drug resistance.

Fukuda Y, Schuetz JD.

Biochem Pharmacol. 2012 Apr 15;83(8):1073-83. doi: 10.1016/j.bcp.2011.12.042. Epub 2012 Jan 20. Review.

17.

Photoaffinity labeling of the multidrug resistance protein 2 (ABCC2/cMOAT) with a photoreactive analog of LTC(4).

Leimanis ML, Karwatsky J, Georges E.

Int J Biochem Mol Biol. 2011;2(1):39-46. Epub 2010 Dec 15.

18.

Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases.

Chen ZS, Tiwari AK.

FEBS J. 2011 Sep;278(18):3226-45. doi: 10.1111/j.1742-4658.2011.08235.x. Epub 2011 Aug 1. Review.

19.

In vitro folding and assembly of the Escherichia coli ATP-binding cassette transporter, BtuCD.

Di Bartolo ND, Hvorup RN, Locher KP, Booth PJ.

J Biol Chem. 2011 May 27;286(21):18807-15. doi: 10.1074/jbc.M110.176891. Epub 2011 Feb 23.

20.

MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury.

Bridges CC, Joshee L, Zalups RK.

Toxicol Appl Pharmacol. 2011 Feb 15;251(1):50-8. doi: 10.1016/j.taap.2010.11.015. Epub 2010 Dec 4.

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