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Structural and Functional Study of Apoptosis-linked Gene-2·Heme-binding Protein 2 Interactions in HIV-1 Production.

Ma J, Zhang X, Feng Y, Zhang H, Wang X, Zheng Y, Qiao W, Liu X.

J Biol Chem. 2016 Dec 23;291(52):26670-26685. doi: 10.1074/jbc.M116.752444.


Multifaceted Roles of ALG-2 in Ca(2+)-Regulated Membrane Trafficking.

Maki M, Takahara T, Shibata H.

Int J Mol Sci. 2016 Aug 26;17(9). pii: E1401. doi: 10.3390/ijms17091401. Review.


ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction.

Sun S, Zhou X, Corvera J, Gallick GE, Lin SH, Kuang J.

Cell Discov. 2015 Jul 21;1:15018. doi: 10.1038/celldisc.2015.18. Erratum in: Cell Discov. 2016;2:16023.


Luteinizing hormone inhibits cisplatin-induced apoptosis in human epithelial ovarian cancer cells.

Xia L, Wen H, Han X, Tang J, Huang Y.

Oncol Lett. 2016 Mar;11(3):1943-1947.


The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles.

Frej AD, Clark J, Le Roy CI, Lilla S, Thomason PA, Otto GP, Churchill G, Insall RH, Claus SP, Hawkins P, Stephens L, Williams RS.

Mol Cell Biol. 2016 May 2;36(10):1464-79. doi: 10.1128/MCB.00039-16.


Twenty Years of Presenilins--Important Proteins in Health and Disease.

Walter J.

Mol Med. 2015 Oct 27;21 Suppl 1:S41-8. doi: 10.2119/molmed.2015.00163.


Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.

Xia D, Watanabe H, Wu B, Lee SH, Li Y, Tsvetkov E, Bolshakov VY, Shen J, Kelleher RJ 3rd.

Neuron. 2015 Mar 4;85(5):967-81. doi: 10.1016/j.neuron.2015.02.010.


Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.

Takahashi T, Kojima K, Zhang W, Sasaki K, Ito M, Suzuki H, Kawasaki M, Wakatsuki S, Takahara T, Shibata H, Maki M.

Int J Mol Sci. 2015 Feb 6;16(2):3677-99. doi: 10.3390/ijms16023677.


Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repair.

Scheffer LL, Sreetama SC, Sharma N, Medikayala S, Brown KJ, Defour A, Jaiswal JK.

Nat Commun. 2014 Dec 23;5:5646. doi: 10.1038/ncomms6646.


ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.

la Cour JM, Schindler AJ, Berchtold MW, Schekman R.

PLoS One. 2013 Sep 19;8(9):e75309. doi: 10.1371/journal.pone.0075309.


Variations in the PDCD6 gene are associated with increased uterine leiomyoma risk in the Chinese.

Zhang K, Zhou B, Shi S, Song Y, Zhang L.

Genet Test Mol Biomarkers. 2013 Jul;17(7):524-8. doi: 10.1089/gtmb.2012.0461.


Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection.

Tamayev R, Akpan N, Arancio O, Troy CM, D'Adamio L.

Mol Neurodegener. 2012 Dec 10;7:60. doi: 10.1186/1750-1326-7-60.


The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease.

Ihara Y, Morishima-Kawashima M, Nixon R.

Cold Spring Harb Perspect Med. 2012 Aug 1;2(8). pii: a006361. doi: 10.1101/cshperspect.a006361.


Prediction of a new ligand-binding site for type 2 motif based on the crystal structure of ALG-2 by dry and wet approaches.

Takahashi T, Suzuki H, Inuzuka T, Shibata H, Maki M.

Int J Mol Sci. 2012;13(6):7532-49. doi: 10.3390/ijms13067532.


Predicting Ca2+ -binding sites using refined carbon clusters.

Zhao K, Wang X, Wong HC, Wohlhueter R, Kirberger MP, Chen G, Yang JJ.

Proteins. 2012 Dec;80(12):2666-79. doi: 10.1002/prot.24149.


PDCD6 is an independent predictor of progression free survival in epithelial ovarian cancer.

Su D, Xu H, Feng J, Gao Y, Gu L, Ying L, Katsaros D, Yu H, Xu S, Qi M.

J Transl Med. 2012 Feb 27;10:31. doi: 10.1186/1479-5876-10-31.


A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis.

Starr TK, Scott PM, Marsh BM, Zhao L, Than BL, O'Sullivan MG, Sarver AL, Dupuy AJ, Largaespada DA, Cormier RT.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5765-70. doi: 10.1073/pnas.1018012108.


Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition.

Inuzuka T, Suzuki H, Kawasaki M, Shibata H, Wakatsuki S, Maki M.

BMC Struct Biol. 2010 Aug 6;10:25. doi: 10.1186/1472-6807-10-25.

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