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Items: 1 to 20 of 23


Adverse effects of mefloquine for the treatment of uncomplicated malaria in Thailand: A pooled analysis of 19, 850 individual patients.

Lee SJ, Ter Kuile FO, Price RN, Luxemburger C, Nosten F.

PLoS One. 2017 Feb 13;12(2):e0168780. doi: 10.1371/journal.pone.0168780. eCollection 2017.


Resistant Malaria : Current Concepts and Therapeutic Strategies.

Kalra SP, Naithani N, Mehta SR, Kumar R.

Med J Armed Forces India. 2002 Jul;58(3):228-33. doi: 10.1016/S0377-1237(02)80136-8. Epub 2011 Jul 21. Review. No abstract available.


Artesunate-mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial.

Grigg MJ, William T, Menon J, Dhanaraj P, Barber BE, Wilkes CS, von Seidlein L, Rajahram GS, Pasay C, McCarthy JS, Price RN, Anstey NM, Yeo TW.

Lancet Infect Dis. 2016 Feb;16(2):180-188. doi: 10.1016/S1473-3099(15)00415-6. Epub 2015 Nov 19.


Thiamin supplementation does not reduce the frequency of adverse events after anti-malarial therapy among patients with falciparum malaria in southern Laos.

Mayxay M, Khanthavong M, Cox L, Sichanthongthip O, Imwong M, Pongvongsa T, Hongvanthong B, Phompida S, Vanisaveth V, White NJ, Newton PN.

Malar J. 2014 Jul 15;13:275. doi: 10.1186/1475-2875-13-275.


Investigation of the in vitro gender-specific partitioning of mefloquine in malarial infected red blood cells and plasma.

Seethorn N, Wernsdorfer WH, Noedl H, Karbwang J, Na-Bangchang K.

Am J Trop Med Hyg. 2013 Oct;89(4):737-41. doi: 10.4269/ajtmh.13-0328. Epub 2013 Sep 3.


Efficacy and tolerability of a new formulation of artesunate-mefloquine for the treatment of uncomplicated malaria in adult in Senegal: open randomized trial.

Tine RC, Faye B, Sylla K, Ndiaye JL, Ndiaye M, Sow D, Lo AC, Abiola A, Ba MC, Gaye O.

Malar J. 2012 Dec 12;11:416. doi: 10.1186/1475-2875-11-416.


Primaquine radical cure of Plasmodium vivax: a critical review of the literature.

John GK, Douglas NM, von Seidlein L, Nosten F, Baird JK, White NJ, Price RN.

Malar J. 2012 Aug 17;11:280. doi: 10.1186/1475-2875-11-280. Review.


Artesunate-mefloquine combination therapy in acute Plasmodium falciparum malaria in young children: a field study regarding neurological and neuropsychiatric safety.

Frey SG, Chelo D, Kinkela MN, Djoukoue F, Tietche F, Hatz C, Weber P.

Malar J. 2010 Oct 21;9:291. doi: 10.1186/1475-2875-9-291.


Mefloquine damage vestibular hair cells in organotypic cultures.

Yu D, Ding D, Jiang H, Stolzberg D, Salvi R.

Neurotox Res. 2011 Jul;20(1):51-8. doi: 10.1007/s12640-010-9221-z. Epub 2010 Sep 22.


A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia.

Kamgno J, Djomo PN, Pion SD, Thylefors B, Boussinesq M.

Am J Trop Med Hyg. 2010 Mar;82(3):379-85. doi: 10.4269/ajtmh.2010.09-0573.


The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria.

Ambler MT, Dubowitz LM, Arunjerdja R, Hla EP, Thwai KL, Viladpainguen J, Singhasivanon P, Luxemburger C, Nosten F, McGready R.

Malar J. 2009 Sep 2;8:207. doi: 10.1186/1475-2875-8-207.


Mefloquine-induced disruption of calcium homeostasis in mammalian cells is similar to that induced by ionomycin.

Caridha D, Yourick D, Cabezas M, Wolf L, Hudson TH, Dow GS.

Antimicrob Agents Chemother. 2008 Feb;52(2):684-93. Epub 2007 Nov 12.


Utility of alkylaminoquinolinyl methanols as new antimalarial drugs.

Dow GS, Heady TN, Bhattacharjee AK, Caridha D, Gerena L, Gettayacamin M, Lanteri CA, Obaldia N 3rd, Roncal N, Shearer T, Smith PL, Tungtaeng A, Wolf L, Cabezas M, Yourick D, Smith KS.

Antimicrob Agents Chemother. 2006 Dec;50(12):4132-43. Epub 2006 Sep 11.


Mefloquine induces dose-related neurological effects in a rat model.

Dow G, Bauman R, Caridha D, Cabezas M, Du F, Gomez-Lobo R, Park M, Smith K, Cannard K.

Antimicrob Agents Chemother. 2006 Mar;50(3):1045-53.


Antimalarial activities of new pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives.

Guan J, Zhang Q, O'Neil M, Obaldia N 3rd, Ager A, Gerena L, Lin AJ.

Antimicrob Agents Chemother. 2005 Dec;49(12):4928-33.


The antimalarial potential of 4-quinolinecarbinolamines may be limited due to neurotoxicity and cross-resistance in mefloquine-resistant Plasmodium falciparum strains.

Dow GS, Koenig ML, Wolf L, Gerena L, Lopez-Sanchez M, Hudson TH, Bhattacharjee AK.

Antimicrob Agents Chemother. 2004 Jul;48(7):2624-32.


Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice.

Barraud de Lagerie S, Comets E, Gautrand C, Fernandez C, Auchere D, Singlas E, Mentre F, Gimenez F.

Br J Pharmacol. 2004 Apr;141(7):1214-22. Epub 2004 Mar 15.


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