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Items: 1 to 20 of 390

1.

Mathematical Modeling of Protein Misfolding Mechanisms in Neurological Diseases: A Historical Overview.

Carbonell F, Iturria-Medina Y, Evans AC.

Front Neurol. 2018 Feb 2;9:37. doi: 10.3389/fneur.2018.00037. eCollection 2018. Review.

2.

An Aged Canid with Behavioral Deficits Exhibits Blood and Cerebrospinal Fluid Amyloid Beta Oligomers.

Rusbridge C, Salguero FJ, David MA, Faller KME, Bras JT, Guerreiro RJ, Richard-Londt AC, Grainger D, Head E, Brandner SGP, Summers B, Hardy J, Tayebi M.

Front Aging Neurosci. 2018 Jan 30;10:7. doi: 10.3389/fnagi.2018.00007. eCollection 2018.

3.

Amyloid fibril polymorphism: a challenge for molecular imaging and therapy.

Fändrich M, Nyström S, Nilsson KPR, Böckmann A, LeVine H 3rd, Hammarström P.

J Intern Med. 2018 Mar;283(3):218-237. doi: 10.1111/joim.12732. Epub 2018 Feb 19.

PMID:
29360284
4.

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.

Huynh TV, Liao F, Francis CM, Robinson GO, Serrano JR, Jiang H, Roh J, Finn MB, Sullivan PM, Esparza TJ, Stewart FR, Mahan TE, Ulrich JD, Cole T, Holtzman DM.

Neuron. 2017 Dec 6;96(5):1013-1023.e4. doi: 10.1016/j.neuron.2017.11.014.

PMID:
29216448
5.

Short Aβ peptides attenuate Aβ42 toxicity in vivo.

Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, Rincon-Limas D, Fernandez-Funez P, Golde TE.

J Exp Med. 2018 Jan 2;215(1):283-301. doi: 10.1084/jem.20170600. Epub 2017 Dec 5.

PMID:
29208777
6.

Heparin-dependent aggregation of hen egg white lysozyme reveals two distinct mechanisms of amyloid fibrillation.

Nitani A, Muta H, Adachi M, So M, Sasahara K, Sakurai K, Chatani E, Naoe K, Ogi H, Hall D, Goto Y.

J Biol Chem. 2017 Dec 29;292(52):21219-21230. doi: 10.1074/jbc.M117.813097. Epub 2017 Nov 3.

PMID:
29101231
7.

Comparing the Aggregation Free Energy Landscapes of Amyloid Beta(1-42) and Amyloid Beta(1-40).

Zheng W, Tsai MY, Wolynes PG.

J Am Chem Soc. 2017 Nov 22;139(46):16666-16676. doi: 10.1021/jacs.7b08089. Epub 2017 Nov 7.

8.

Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42.

An SSA, Lee BS, Yu JS, Lim K, Kim GJ, Lee R, Kim S, Kang S, Park YH, Wang MJ, Yang YS, Youn YC, Kim S.

Alzheimers Res Ther. 2017 Oct 17;9(1):86. doi: 10.1186/s13195-017-0310-6.

9.

Prying into the Prion Hypothesis for Parkinson's Disease.

Brundin P, Melki R.

J Neurosci. 2017 Oct 11;37(41):9808-9818. doi: 10.1523/JNEUROSCI.1788-16.2017. Review.

PMID:
29021298
10.

Identification of key regions and residues controlling Aβ folding and assembly.

Hayden EY, Hoi KK, Lopez J, Inayathullah M, Condron MM, Teplow DB.

Sci Rep. 2017 Oct 3;7(1):12434. doi: 10.1038/s41598-017-10845-6.

11.

Absolute Quantification of Amyloid Propagons by Digital Microfluidics.

Pfammatter M, Andreasen M, Meisl G, Taylor CG, Adamcik J, Bolisetty S, Sánchez-Ferrer A, Klenerman D, Dobson CM, Mezzenga R, Knowles TPJ, Aguzzi A, Hornemann S.

Anal Chem. 2017 Nov 21;89(22):12306-12313. doi: 10.1021/acs.analchem.7b03279. Epub 2017 Nov 1.

12.

Characterization of Soft Amyloid Cores in Human Prion-Like Proteins.

Batlle C, de Groot NS, Iglesias V, Navarro S, Ventura S.

Sci Rep. 2017 Sep 21;7(1):12134. doi: 10.1038/s41598-017-09714-z.

13.

Asparagine and glutamine ladders promote cross-species prion conversion.

Kurt TD, Aguilar-Calvo P, Jiang L, Rodriguez JA, Alderson N, Eisenberg DS, Sigurdson CJ.

J Biol Chem. 2017 Nov 17;292(46):19076-19086. doi: 10.1074/jbc.M117.794107. Epub 2017 Sep 20.

PMID:
28931606
14.

Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo.

Sowade RF, Jahn TR.

Nat Commun. 2017 Sep 11;8(1):512. doi: 10.1038/s41467-017-00579-4.

15.

Amyloid β-42 induces neuronal apoptosis by targeting mitochondria.

Han XJ, Hu YY, Yang ZJ, Jiang LP, Shi SL, Li YR, Guo MY, Wu HL, Wan YY.

Mol Med Rep. 2017 Oct;16(4):4521-4528. doi: 10.3892/mmr.2017.7203. Epub 2017 Aug 10.

16.

Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type.

Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E.

Sci Rep. 2017 Aug 21;7(1):9008. doi: 10.1038/s41598-017-08720-5.

17.

The Role of Microglia in Prion Diseases: A Paradigm of Functional Diversity.

Obst J, Simon E, Mancuso R, Gomez-Nicola D.

Front Aging Neurosci. 2017 Jun 23;9:207. doi: 10.3389/fnagi.2017.00207. eCollection 2017. Review.

18.

Aβ seeds and prions: How close the fit?

Rasmussen J, Jucker M, Walker LC.

Prion. 2017 Jul 4;11(4):215-225. doi: 10.1080/19336896.2017.1334029. Epub 2017 Jun 28.

19.

Fibril formation from the amyloid-β peptide is governed by a dynamic equilibrium involving association and dissociation of the monomer.

Hoshino M.

Biophys Rev. 2017 Feb;9(1):9-16. doi: 10.1007/s12551-016-0217-7. Epub 2016 Aug 25. Review.

20.

Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer's Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data.

Kocis P, Tolar M, Yu J, Sinko W, Ray S, Blennow K, Fillit H, Hey JA.

CNS Drugs. 2017 Jun;31(6):495-509. doi: 10.1007/s40263-017-0434-z.

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