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Items: 1 to 20 of 107

1.

Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression.

Liao KH, Chang SJ, Chang HC, Chien CL, Huang TS, Feng TC, Lin WW, Shih CC, Yang MH, Yang SH, Lin CH, Hwang WL, Lee OK.

PLoS One. 2017 Jun 22;12(6):e0179758. doi: 10.1371/journal.pone.0179758. eCollection 2017.

2.

Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation.

Thiel VN, Giaimo BD, Schwarz P, Soller K, Vas V, Bartkuhn M, Blätte TJ, Döhner K, Bullinger L, Borggrefe T, Geiger H, Oswald F.

Leukemia. 2017 Nov;31(11):2491-2502. doi: 10.1038/leu.2017.105. Epub 2017 Mar 31.

3.

Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine.

Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, Guan JL, Mulloy JC, Kumar A, Zheng Y.

Autophagy. 2017 May 4;13(5):955-966. doi: 10.1080/15548627.2017.1287652. Epub 2017 Feb 15.

PMID:
28282266
4.

New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.

Li J, Guo C, Steinauer N, Zhang J.

Front Biol (Beijing). 2016 Aug;11(4):285-304. doi: 10.1007/s11515-016-1415-1. Epub 2016 Sep 3.

5.

Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation.

Link KA, Lin S, Shrestha M, Bowman M, Wunderlich M, Bloomfield CD, Huang G, Mulloy JC.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9075-80. doi: 10.1073/pnas.1524225113. Epub 2016 Jul 25.

6.

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units.

Wehbi VL, Taskén K.

Front Immunol. 2016 Jun 8;7:222. doi: 10.3389/fimmu.2016.00222. eCollection 2016. Review.

7.

Co-repressor CBFA2T2 regulates pluripotency and germline development.

Tu S, Narendra V, Yamaji M, Vidal SE, Rojas LA, Wang X, Kim SY, Garcia BA, Tuschl T, Stadtfeld M, Reinberg D.

Nature. 2016 Jun 16;534(7607):387-90. doi: 10.1038/nature18004. Epub 2016 Jun 8.

8.

MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.

Kohrs N, Kolodziej S, Kuvardina ON, Herglotz J, Yillah J, Herkt S, Piechatzek A, Salinas Riester G, Lingner T, Wichmann C, Bonig H, Seifried E, Platzbecker U, Medyouf H, Grez M, Lausen J.

PLoS Genet. 2016 Mar 18;12(3):e1005946. doi: 10.1371/journal.pgen.1005946. eCollection 2016 Mar.

9.

Core Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic Opportunities.

Sinha C, Cunningham LC, Liu PP.

Semin Hematol. 2015 Jul;52(3):215-22. doi: 10.1053/j.seminhematol.2015.04.002. Epub 2015 Apr 7. Review.

10.

Loss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasis.

Mizutani S, Yoshida T, Zhao X, Nimer SD, Taniwaki M, Okuda T.

Br J Haematol. 2015 Sep;170(6):859-73. doi: 10.1111/bjh.13499. Epub 2015 May 26.

11.

Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

Kumar P, Gullberg U, Olsson I, Ajore R.

PLoS One. 2015 May 14;10(5):e0123725. doi: 10.1371/journal.pone.0123725. eCollection 2015.

12.

Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury.

Poindexter SV, Reddy VK, Mittal MK, Williams AM, Washington MK, Harris E, Mah A, Hiebert SW, Singh K, Chaturvedi R, Wilson KT, Lund PK, Williams CS.

Am J Physiol Gastrointest Liver Physiol. 2015 Mar 15;308(6):G562-71. doi: 10.1152/ajpgi.00253.2014. Epub 2015 Jan 8.

13.

An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development.

Benitez CM, Qu K, Sugiyama T, Pauerstein PT, Liu Y, Tsai J, Gu X, Ghodasara A, Arda HE, Zhang J, Dekker JD, Tucker HO, Chang HY, Kim SK.

PLoS Genet. 2014 Oct 16;10(10):e1004645. doi: 10.1371/journal.pgen.1004645. eCollection 2014 Oct.

14.

Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Ptasinska A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C.

Cell Rep. 2014 Sep 25;8(6):1974-1988. doi: 10.1016/j.celrep.2014.08.024. Epub 2014 Sep 18.

15.

FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels.

Chen L, Luo LF, Lu J, Li L, Liu YF, Wang J, Liu H, Song H, Jiang H, Chen SJ, Luo C, Li KK.

PLoS One. 2014 Jul 22;9(7):e103033. doi: 10.1371/journal.pone.0103033. eCollection 2014.

16.

A new inducible model for t(8;21) AML.

Mulloy JC.

EMBO Mol Med. 2013 Dec;5(12):1795-7. doi: 10.1002/emmm.201303483. Epub 2013 Nov 4. No abstract available.

17.

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.

Cabezas-Wallscheid N, Eichwald V, de Graaf J, Löwer M, Lehr HA, Kreft A, Eshkind L, Hildebrandt A, Abassi Y, Heck R, Dehof AK, Ohngemach S, Sprengel R, Wörtge S, Schmitt S, Lotz J, Meyer C, Kindler T, Zhang DE, Kaina B, Castle JC, Trumpp A, Sahin U, Bockamp E.

EMBO Mol Med. 2013 Dec;5(12):1804-20. doi: 10.1002/emmm.201302661. Epub 2013 Oct 4.

18.

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration.

Kumar P, Sharoyko VV, Spégel P, Gullberg U, Mulder H, Olsson I, Ajore R.

PLoS One. 2013 Jul 1;8(7):e68502. doi: 10.1371/journal.pone.0068502. Print 2013.

19.

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG.

Nature. 2013 Aug 1;500(7460):93-7. doi: 10.1038/nature12287. Epub 2013 Jun 30.

20.

RUNX1: A microRNA hub in normal and malignant hematopoiesis.

Rossetti S, Sacchi N.

Int J Mol Sci. 2013 Jan 14;14(1):1566-88. doi: 10.3390/ijms14011566. Review.

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