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Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology.

Patel D, Lakhkar A, Wolin MS.

Adv Exp Med Biol. 2017;967:227-240. doi: 10.1007/978-3-319-63245-2_13.


A PP2A-mediated feedback mechanism controls Ca2+-dependent NO synthesis under physiological oxygen.

Keeley TP, Siow RCM, Jacob R, Mann GE.

FASEB J. 2017 Dec;31(12):5172-5183. doi: 10.1096/fj.201700211R. Epub 2017 Jul 31.


Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia.

Chen J, Khalil RA.

Prog Mol Biol Transl Sci. 2017;148:87-165. doi: 10.1016/bs.pmbts.2017.04.001. Epub 2017 May 22. Review.


Inducible nitric oxide synthase (NOS-2) in subarachnoid hemorrhage: Regulatory mechanisms and therapeutic implications.

Iqbal S, Hayman EG, Hong C, Stokum JA, Kurland DB, Gerzanich V, Simard JM.

Brain Circ. 2016;2(1):8-19.


Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia.

Possomato-Vieira JS, Khalil RA.

Adv Pharmacol. 2016;77:361-431. doi: 10.1016/bs.apha.2016.04.008. Epub 2016 Jun 14.


Immature endothelial cells initiate endothelin-mediated constriction of newborn arteries.

Chang F, Flavahan S, Flavahan NA.

J Physiol. 2016 Sep 1;594(17):4933-44. doi: 10.1113/JP272176. Epub 2016 Jun 16.


Endothelin Receptor A Antagonism and Fetal Growth in Endothelial Nitric Oxide Synthase Gene Knockout Maternal and Fetal Mice.

Luo K, Thaete LG, Neerhof MG.

Reprod Sci. 2016 Aug;23(8):1028-36. doi: 10.1177/1933719115625839. Epub 2016 Jan 19.


Endotoxemia Induces IκBβ/NF-κB-Dependent Endothelin-1 Expression in Hepatic Macrophages.

McKenna S, Gossling M, Bugarini A, Hill E, Anderson AL, Rancourt RC, Balasubramaniyan N, El Kasmi KC, Wright CJ.

J Immunol. 2015 Oct 15;195(8):3866-79. doi: 10.4049/jimmunol.1501017. Epub 2015 Sep 4.


Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia.

Shah DA, Khalil RA.

Biochem Pharmacol. 2015 Jun 15;95(4):211-26. doi: 10.1016/j.bcp.2015.04.012. Epub 2015 Apr 24. Review.


Inhaled nitric oxide alters the distribution of blood flow in the healthy human lung, suggesting active hypoxic pulmonary vasoconstriction in normoxia.

Asadi AK, Sá RC, Kim NH, Theilmann RJ, Hopkins SR, Buxton RB, Prisk GK.

J Appl Physiol (1985). 2015 Feb 1;118(3):331-43. doi: 10.1152/japplphysiol.01354.2013. Epub 2014 Nov 26.


Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction--a novel mechanism for maintaining vascular function.

Shao Y, Cheng Z, Li X, Chernaya V, Wang H, Yang XF.

J Hematol Oncol. 2014 Oct 31;7:80. doi: 10.1186/s13045-014-0080-6. Review.


Endothelial cells mediate islet-specific maturation of human embryonic stem cell-derived pancreatic progenitor cells.

Jaramillo M, Mathew S, Mamiya H, Goh SK, Banerjee I.

Tissue Eng Part A. 2015 Jan;21(1-2):14-25. doi: 10.1089/ten.TEA.2014.0013. Epub 2014 Aug 19.


The therapeutic potential of antioxidants, ER chaperones, NO and H2S donors, and statins for treatment of preeclampsia.

Cindrova-Davies T.

Front Pharmacol. 2014 May 27;5:119. doi: 10.3389/fphar.2014.00119. eCollection 2014. Review.


Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia.

Cotechini T, Komisarenko M, Sperou A, Macdonald-Goodfellow S, Adams MA, Graham CH.

J Exp Med. 2014 Jan 13;211(1):165-79. doi: 10.1084/jem.20130295. Epub 2014 Jan 6.


Role of endothelin in uteroplacental circulation and fetal vascular function.

Paradis A, Zhang L.

Curr Vasc Pharmacol. 2013 Sep;11(5):594-605. Review.


Vasotrophic regulation of age-dependent hypoxic cerebrovascular remodeling.

Silpanisong J, Pearce WJ.

Curr Vasc Pharmacol. 2013 Sep;11(5):544-63. Review.


A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury.

Stewart RK, Dangi A, Huang C, Murase N, Kimura S, Stolz DB, Wilson GC, Lentsch AB, Gandhi CR.

J Hepatol. 2014 Feb;60(2):298-305. doi: 10.1016/j.jhep.2013.09.013. Epub 2013 Sep 20.


S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

Nott A, Nitarska J, Veenvliet JV, Schacke S, Derijck AA, Sirko P, Muchardt C, Pasterkamp RJ, Smidt MP, Riccio A.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3113-8. doi: 10.1073/pnas.1218126110. Epub 2013 Jan 28.


Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis.

Arefiev K, Fiorentino DF, Chung L.

Int J Rheumatol. 2011;2011:201787. doi: 10.1155/2011/201787. Epub 2011 Oct 27.


L-arginine supplementation abolishes the blood pressure and endothelin response to chronic increases in plasma sFlt-1 in pregnant rats.

Murphy SR, LaMarca B, Cockrell K, Arany M, Granger JP.

Am J Physiol Regul Integr Comp Physiol. 2012 Jan 15;302(2):R259-63. doi: 10.1152/ajpregu.00319.2011. Epub 2011 Nov 9.

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