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Items: 1 to 20 of 112


Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer.

Durairaj C, Ruiz-Garcia A, Gauthier ER, Huang X, Lu DR, Hoffman JT, Finn RS, Joy AA, Ettl J, Rugo HS, Zheng J, Wilner KD, Wang DD.

Anticancer Drugs. 2018 Mar;29(3):271-280. doi: 10.1097/CAD.0000000000000589.


Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology?

Lane JD, Tinker A.

Front Physiol. 2017 Nov 6;8:890. doi: 10.3389/fphys.2017.00890. eCollection 2017. Review.


Drugs and life-threatening ventricular arrhythmia risk: results from the DARE study cohort.

Coughtrie AL, Behr ER, Layton D, Marshall V, Camm AJ, Shakir SAW.

BMJ Open. 2017 Oct 16;7(10):e016627. doi: 10.1136/bmjopen-2017-016627.


A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias.

Yang PC, Perissinotti LL, López-Redondo F, Wang Y, DeMarco KR, Jeng MT, Vorobyov I, Harvey RD, Kurokawa J, Noskov SY, Clancy CE.

J Physiol. 2017 Jul 15;595(14):4695-4723. doi: 10.1113/JP273142. Epub 2017 Jun 14.


Catheter Ablation of Atrial Fibrillation in Females.

Dugo D, Bordignon S, Perrotta L, Fürnkranz A, Julian Chun KR, Schmidt B.

J Atr Fibrillation. 2013 Jun 30;6(1):893. doi: 10.4022/jafib.893. eCollection 2013 Jun-Jul. Review.


Atrioventricular block and pause-dependent torsade de pointes.

Dohadwala M, Kamili F, Estes NM Rd, Homoud M.

HeartRhythm Case Rep. 2016 Nov 2;3(2):115-119. doi: 10.1016/j.hrcr.2016.08.006. eCollection 2017 Feb. No abstract available.


Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

Tisdale JE, Jaynes HA, Overholser BR, Sowinski KM, Flockhart DA, Kovacs RJ.

JACC Clin Electrophysiol. 2016 Dec;2(7):765-774. doi: 10.1016/j.jacep.2016.02.015.


Hypokalemia in women and methadone therapy are the strongest non-cardiologic factors associated with QT prolongation in an emergency department setting.

Marill KA, Miller ES.

J Electrocardiol. 2017 Jul - Aug;50(4):416-423. doi: 10.1016/j.jelectrocard.2017.02.001. Epub 2017 Feb 10.


Cardiac Channelopathies and Sudden Death: Recent Clinical and Genetic Advances.

Fernández-Falgueras A, Sarquella-Brugada G, Brugada J, Brugada R, Campuzano O.

Biology (Basel). 2017 Jan 29;6(1). pii: E7. doi: 10.3390/biology6010007. Review.


Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.

Stillitano F, Hansen J, Kong CW, Karakikes I, Funck-Brentano C, Geng L, Scott S, Reynier S, Wu M, Valogne Y, Desseaux C, Salem JE, Jeziorowska D, Zahr N, Li R, Iyengar R, Hajjar RJ, Hulot JS.

Elife. 2017 Jan 30;6. pii: e19406. doi: 10.7554/eLife.19406.


Sex based subgroup differences in randomized controlled trials: empirical evidence from Cochrane meta-analyses.

Wallach JD, Sullivan PG, Trepanowski JF, Steyerberg EW, Ioannidis JP.

BMJ. 2016 Nov 24;355:i5826. doi: 10.1136/bmj.i5826.


The association between pro-arrhythmic agents and aortic stenosis in young adults: is it sufficient to clarify the sudden unexpected deaths?

Radnic B, Radojevic N, Vucinic J, Duborija-Kovacevic N.

Cardiol Young. 2017 Jul;27(5):929-935. doi: 10.1017/S1047951116001864. Epub 2016 Nov 8.


Molecular Pathophysiology of Congenital Long QT Syndrome.

Bohnen MS, Peng G, Robey SH, Terrenoire C, Iyer V, Sampson KJ, Kass RS.

Physiol Rev. 2017 Jan;97(1):89-134. Review.


Atrial fibrillation in women: treatment.

Ko D, Rahman F, Martins MA, Hylek EM, Ellinor PT, Schnabel RB, Benjamin EJ, Christophersen IE.

Nat Rev Cardiol. 2017 Feb;14(2):113-124. doi: 10.1038/nrcardio.2016.171. Epub 2016 Oct 27. Review.


Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes.

Kurokawa J, Kodama M, Clancy CE, Furukawa T.

Pharmacol Ther. 2016 Dec;168:23-28. doi: 10.1016/j.pharmthera.2016.09.004. Epub 2016 Sep 4. Review.


Risk-factors for methadone-specific deaths in Scotland's methadone-prescription clients between 2009 and 2013.

Gao L, Dimitropoulou P, Robertson JR, McTaggart S, Bennie M, Bird SM.

Drug Alcohol Depend. 2016 Oct 1;167:214-23. doi: 10.1016/j.drugalcdep.2016.08.627. Epub 2016 Aug 29.


Methadone prolongs cardiac conduction in young patients with cancer-related pain.

Anghelescu DL, Patel RM, Mahoney DP, Trujillo L, Faughnan LG, Steen BD, Baker JN, Pei D.

J Opioid Manag. 2016 May-Jun;12(2):131-8. doi: 10.5055/jom.2016.0325.


Deletion of Kvβ1.1 subunit leads to electrical and haemodynamic changes causing cardiac hypertrophy in female murine hearts.

Tur J, Chapalamadugu KC, Padawer T, Badole SL, Kilfoil PJ 2nd, Bhatnagar A, Tipparaju SM.

Exp Physiol. 2016 Apr;101(4):494-508. doi: 10.1113/EP085405. Epub 2016 Feb 25.


Strategies and methods to study female-specific cardiovascular health and disease: a guide for clinical scientists.

Ouyang P, Wenger NK, Taylor D, Rich-Edwards JW, Steiner M, Shaw LJ, Berga SL, Miller VM, Merz NB.

Biol Sex Differ. 2016 Mar 31;7:19. doi: 10.1186/s13293-016-0073-y. eCollection 2016. Review.


Drug-Induced Long-QT and Torsades de Pointes in Elderly Polymedicated Patients.

García-Fuertes D, Villanueva-Fernández E, Crespín-Crespín M.

Arq Bras Cardiol. 2016 Feb;106(2):156-9. doi: 10.5935/abc.20150069. English, Portuguese. No abstract available.

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