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Items: 1 to 20 of 115


CYP2C19*2 and CYP2C19*17 variants and effect of tamoxifen on breast cancer recurrence: Analysis of the International Tamoxifen Pharmacogenomics Consortium dataset.

Damkier P, Kjærsgaard A, Barker KA, Cronin-Fenton D, Crawford A, Hellberg Y, Janssen EAM, Langefeld C, Ahern TP, Lash TL.

Sci Rep. 2017 Aug 10;7(1):7727. doi: 10.1038/s41598-017-08091-x.


Early effect on intragastric pH of oral administration of rabeprazole with mosapride compared with rabeprazole alone.

Iida H, Kaai M, Inoh Y, Kanoshima K, Ohkuma K, Nonaka T, Fujita K, Ida T, Kusakabe A, Maeda S, Nakajima A, Inamori M.

Ann Gastroenterol. 2017;30(4):424-428. doi: 10.20524/aog.2017.0161. Epub 2017 May 19.


Effect of CYP2C19 Gene Polymorphisms on Proton Pump Inhibitor, Amoxicillin, and Levofloxacin Triple Therapy for Eradication of Helicobacter Pylori.

Lin YA, Wang H, Gu ZJ, Wang WJ, Zeng XY, Du YL, Ying SS, Zhang BH.

Med Sci Monit. 2017 Jun 3;23:2701-2707.


The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics.

Amin AM, Sheau Chin L, Azri Mohamed Noor D, Sk Abdul Kader MA, Kah Hay Y, Ibrahim B.

Cardiol Res Pract. 2017;2017:8062796. doi: 10.1155/2017/8062796. Epub 2017 Mar 21. Review.


Pantoprazole Does Not Reduce the Antiplatelet Effect of Clopidogrel: A Randomized Controlled Trial in Korea.

Choi YJ, Kim N, Jang IJ, Cho JY, Nam RH, Park JH, Jo HJ, Yoon H, Shin CM, Park YS, Lee DH, Jung HC.

Gut Liver. 2017 Jul 15;11(4):504-511. doi: 10.5009/gnl16352.


Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections.

Hamadeh IS, Klinker KP, Borgert SJ, Richards AI, Li W, Mangal N, Hiemenz JW, Schmidt S, Langaee TY, Peloquin CA, Johnson JA, Cavallari LH.

Pharmacogenet Genomics. 2017 May;27(5):190-196. doi: 10.1097/FPC.0000000000000277.


Rapid Naked-Eye Discrimination of Cytochrome P450 Genetic Polymorphism through Non-Crosslinking Aggregation of DNA-Functionalized Gold Nanoparticles.

Akiyama Y, Wang G, Shiraishi S, Kanayama N, Takarada T, Maeda M.

ChemistryOpen. 2016 Nov 23;5(6):508-512. doi: 10.1002/open.201600110. eCollection 2016 Dec.


Population Pharmacokinetics and Pharmacogenetics Analysis of Rilpivirine in HIV-1-Infected Individuals.

Aouri M, Barcelo C, Guidi M, Rotger M, Cavassini M, Hizrel C, Buclin T, Decosterd LA, Csajka C; Swiss HIV Cohort Study.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e00899-16. doi: 10.1128/AAC.00899-16. Print 2017 Jan.


Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data.

Ang GY, Yu CY, Subramaniam V, Abdul Khalid MI, Tuan Abdu Aziz TA, Johari James R, Ahmad A, Abdul Rahman T, Mohd Nor F, Ismail AI, Md Isa K, Salleh H, Teh LK, Salleh MZ.

PLoS One. 2016 Oct 31;11(10):e0164169. doi: 10.1371/journal.pone.0164169. eCollection 2016.


Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision Medicine.

Ahmed S, Zhou Z, Zhou J, Chen SQ.

Genomics Proteomics Bioinformatics. 2016 Oct;14(5):298-313. doi: 10.1016/j.gpb.2016.03.008. Epub 2016 Oct 8. Review.


Phenotyping and genotyping of CYP2C19 using comparative metabolism of proguanil in sickle-cell disease patients and healthy controls in Nigeria.

Adejumo OE, Kotila TR, Falusi AG, Silva BO, Nwogu JN, Fasinu PS, Babalola CP.

Pharmacol Res Perspect. 2016 Aug 22;4(5):e00252. eCollection 2016 Oct.


Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism.

Afzal A, Patel B, Patel N, Sattur S, Patel V.

Case Rep Med. 2016;2016:2312078. doi: 10.1155/2016/2312078. Epub 2016 Jul 31.


Multicenter Study of Antibiotic Resistance Profile of H. pylori and Distribution of CYP2C19 Gene Polymorphism in Rural Population of Chongqing, China.

Han R, Lu H, Jiang MW, Tan KW, Peng Z, Hu JL, Fang DC, Lan CH, Wu XL.

Gastroenterol Res Pract. 2016;2016:8547686. doi: 10.1155/2016/8547686. Epub 2016 May 9.


A Rapid and Accurate Method to Evaluate Helicobacter pylori Infection, Clarithromycin Resistance, and CYP2C19 Genotypes Simultaneously From Gastric Juice.

Kuo CH, Liu CJ, Yang CC, Kuo FC, Hu HM, Shih HY, Wu MC, Chen YH, Wang HM, Ren JL, Wu DC, Chang LL.

Medicine (Baltimore). 2016 May;95(21):e3458. doi: 10.1097/MD.0000000000003458.


Association of CYP2C19 Polymorphisms with the Clinical Efficacy of Clopidogrel Therapy in Patients Undergoing Carotid Artery Stenting in Asia.

Zhu WY, Zhao T, Xiong XY, Li J, Wang L, Zhou Y, Gong ZL, Cheng SY, Liu Y, Shuai J, Yang QW.

Sci Rep. 2016 May 3;6:25478. doi: 10.1038/srep25478.


Association of PON1, P2Y12 and COX1 with Recurrent Ischemic Events in Patients with Extracranial or Intracranial Stenting.

Li XQ, Ma N, Li XG, Wang B, Sun SS, Gao F, Mo DP, Song LG, Sun X, Liu L, Zhao XQ, Wang YL, Wang YJ, Zhao ZG, Miao ZR.

PLoS One. 2016 Feb 12;11(2):e0148891. doi: 10.1371/journal.pone.0148891. eCollection 2016.


Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients.

Lim JS, Sutiman N, Muerdter TE, Singh O, Cheung YB, Ng RC, Yap YS, Wong NS, Ang PC, Dent R, Schroth W, Schwab M, Chowbay B.

Br J Clin Pharmacol. 2016 Jun;81(6):1142-52. doi: 10.1111/bcp.12886. Epub 2016 Mar 8. No abstract available.


Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.

Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS.

Drug Metab Dispos. 2016 Mar;44(3):343-51. doi: 10.1124/dmd.115.067900. Epub 2015 Dec 17. Review.


CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.

Hoh BL, Gong Y, McDonough CW, Waters MF, Royster AJ, Sheehan TO, Burkley B, Langaee TY, Mocco J, Zuckerman SL, Mummareddy N, Stephens ML 2nd, Ingram C, Shaffer CM, Denny JC, Brilliant MH, Kitchner TE, Linneman JG, Roden DM, Johnson JA.

J Neurosurg. 2016 Jun;124(6):1746-51. doi: 10.3171/2015.6.JNS15795. Epub 2015 Nov 20.


Genetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus.

Shu W, Guan S, Yang X, Liang L, Li J, Chen Z, Zhang Y, Chen L, Wang X, Huang M.

Br J Clin Pharmacol. 2016 Feb;81(2):327-40. doi: 10.1111/bcp.12800. Epub 2015 Dec 25.

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