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Items: 1 to 20 of 76


One ring to rule them all: Current trends in combating bacterial resistance to the β-lactams.

King DT, Sobhanifar S, Strynadka NC.

Protein Sci. 2016 Apr;25(4):787-803. doi: 10.1002/pro.2889. Epub 2016 Mar 9. Review.


Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile.

Rajamuthiah R, Jayamani E, Majed H, Conery AL, Kim W, Kwon B, Fuchs BB, Kelso MJ, Ausubel FM, Mylonakis E.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5203-7. doi: 10.1016/j.bmcl.2015.09.066. Epub 2015 Sep 30.


Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa.

Dreier J, Ruggerone P.

Front Microbiol. 2015 Jul 8;6:660. doi: 10.3389/fmicb.2015.00660. eCollection 2015. Review.


Structural basis of RND-type multidrug exporters.

Yamaguchi A, Nakashima R, Sakurai K.

Front Microbiol. 2015 Apr 20;6:327. doi: 10.3389/fmicb.2015.00327. eCollection 2015. Review.


Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Conery AL, Kim W, Jayamani E, Kwon B, Ausubel FM, Mylonakis E.

PLoS One. 2015 Apr 21;10(4):e0124595. doi: 10.1371/journal.pone.0124595. eCollection 2015.


The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Li XZ, Plésiat P, Nikaido H.

Clin Microbiol Rev. 2015 Apr;28(2):337-418. doi: 10.1128/CMR.00117-14. Review.


Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for rapid detection of β-lactam resistance in Enterobacteriaceae derived from blood cultures.

Jung JS, Popp C, Sparbier K, Lange C, Kostrzewa M, Schubert S.

J Clin Microbiol. 2014 Mar;52(3):924-30. doi: 10.1128/JCM.02691-13. Epub 2014 Jan 8.


Permeation rates of penicillins indicate that Escherichia coli porins function principally as nonspecific channels.

Kojima S, Nikaido H.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2629-34. doi: 10.1073/pnas.1310333110. Epub 2013 Jun 24.


Prevalence of PER-1- type Extended-Spectrum Beta-Lactamaes in Clinical Strains of Pseudomonas aeruginosa Isolated from Tabriz, Iran.

Akhi MT, Khalili Y, Ghottaslou R, Aghazadeh M, Seroush Bar Hagh MH, Yousefi S.

Iran J Basic Med Sci. 2012 Jan;15(1):678-82.


Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world.

Galán JC, González-Candelas F, Rolain JM, Cantón R.

Front Microbiol. 2013 Feb 8;4:9. doi: 10.3389/fmicb.2013.00009. eCollection 2013.


MexXY multidrug efflux system of Pseudomonas aeruginosa.

Morita Y, Tomida J, Kawamura Y.

Front Microbiol. 2012 Nov 28;3:408. doi: 10.3389/fmicb.2012.00408. eCollection 2012.


OmpA is the principal nonspecific slow porin of Acinetobacter baumannii.

Sugawara E, Nikaido H.

J Bacteriol. 2012 Aug;194(15):4089-96. doi: 10.1128/JB.00435-12. Epub 2012 May 25.


Structure and mechanism of RND-type multidrug efflux pumps.

Nikaido H.

Adv Enzymol Relat Areas Mol Biol. 2011;77:1-60. Review. No abstract available.


Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin.

Delespaux V, Vitouley HS, Marcotty T, Speybroeck N, Berkvens D, Roy K, Geerts S, Van den Bossche P.

PLoS Negl Trop Dis. 2010 Sep 28;4(9):e828. doi: 10.1371/journal.pntd.0000828.


In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.

Page MG, Dantier C, Desarbre E.

Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302. doi: 10.1128/AAC.01525-09. Epub 2010 Mar 22.


Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Tomás M, Doumith M, Warner M, Turton JF, Beceiro A, Bou G, Livermore DM, Woodford N.

Antimicrob Agents Chemother. 2010 May;54(5):2219-24. doi: 10.1128/AAC.00816-09. Epub 2010 Mar 1.


Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli.

Lim SP, Nikaido H.

Antimicrob Agents Chemother. 2010 May;54(5):1800-6. doi: 10.1128/AAC.01714-09. Epub 2010 Feb 16.


Three decades of beta-lactamase inhibitors.

Drawz SM, Bonomo RA.

Clin Microbiol Rev. 2010 Jan;23(1):160-201. doi: 10.1128/CMR.00037-09. Review.


Efflux-mediated drug resistance in bacteria: an update.

Li XZ, Nikaido H.

Drugs. 2009 Aug 20;69(12):1555-623. doi: 10.2165/11317030-000000000-00000. Review.

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