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Items: 1 to 20 of 43

1.

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.

Zhang J, McCastlain K, Yoshihara H, Xu B, Chang Y, Churchman ML, Wu G, Li Y, Wei L, Iacobucci I, Liu Y, Qu C, Wen J, Edmonson M, Payne-Turner D, Kaufmann KB, Takayanagi SI, Wienholds E, Waanders E, Ntziachristos P, Bakogianni S, Wang J, Aifantis I, Roberts KG, Ma J, Song G, Easton J, Mulder HL, Chen X, Newman S, Ma X, Rusch M, Gupta P, Boggs K, Vadodaria B, Dalton J, Liu Y, Valentine ML, Ding L, Lu C, Fulton RS, Fulton L, Tabib Y, Ochoa K, Devidas M, Pei D, Cheng C, Yang J, Evans WE, Relling MV, Pui CH, Jeha S, Harvey RC, Chen IL, Willman CL, Marcucci G, Bloomfield CD, Kohlschmidt J, Mrózek K, Paietta E, Tallman MS, Stock W, Foster MC, Racevskis J, Rowe JM, Luger S, Kornblau SM, Shurtleff SA, Raimondi SC, Mardis ER, Wilson RK, Dick JE, Hunger SP, Loh ML, Downing JR, Mullighan CG; St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project..

Nat Genet. 2016 Dec;48(12):1481-1489. doi: 10.1038/ng.3691. Epub 2016 Oct 24.

PMID:
27776115
2.

TDP-43/FUS in motor neuron disease: Complexity and challenges.

Guerrero EN, Wang H, Mitra J, Hegde PM, Stowell SE, Liachko NF, Kraemer BC, Garruto RM, Rao KS, Hegde ML.

Prog Neurobiol. 2016 Oct - Nov;145-146:78-97. doi: 10.1016/j.pneurobio.2016.09.004. Epub 2016 Sep 28. Review.

PMID:
27693252
3.

FUS-linked essential tremor associated with motor dysfunction in Drosophila.

Tio M, Wen R, Lim YL, Wang H, Ling SC, Zhao Y, Tan EK.

Hum Genet. 2016 Nov;135(11):1223-1232. Epub 2016 Jul 9.

4.

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis.

Shang Y, Huang EJ.

Brain Res. 2016 Sep 15;1647:65-78. doi: 10.1016/j.brainres.2016.03.036. Epub 2016 Mar 28. Review.

5.

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors.

Raczynska KD, Ruepp MD, Brzek A, Reber S, Romeo V, Rindlisbacher B, Heller M, Szweykowska-Kulinska Z, Jarmolowski A, Schümperli D.

Nucleic Acids Res. 2015 Nov 16;43(20):9711-28. doi: 10.1093/nar/gkv794. Epub 2015 Aug 6.

6.

The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia.

Sotoca AM, Prange KH, Reijnders B, Mandoli A, Nguyen LN, Stunnenberg HG, Martens JH.

Oncogene. 2016 Apr 14;35(15):1965-76. doi: 10.1038/onc.2015.261. Epub 2015 Jul 6.

7.

Ets Related Gene and Smad3 Proteins Collaborate to Activate Transforming Growth Factor-Beta Mediated Signaling Pathway in ETS Related Gene-Positive Prostate Cancer Cells.

Fang J, Xu H, Yang C, Morsalin S, Kayarthodi S, Rungsrisuriyachai K, Gunnal U, Mckenzie B, Rao VN, Reddy ES.

J Pharm Sci Pharmacol. 2014 Sep 1;1(3):175-181.

8.

Molecular Mechanism of Activation of Transforming Growth Factor Beta/Smads Signaling Pathway in Ets Related Gene-Positive Prostate Cancers.

Fang J, Xu H, Yang C, Kayarthodi S, Matthews R, Rao VN, Reddy ES.

J Pharm Sci Pharmacol. 2014 Mar;1(1):82-85.

9.

Anti-Epileptic Drug Targets Ewing Sarcoma.

Kayarthodi S, Fujimura Y, Fang J, Morsalin S, Rao VN, Reddy ES.

J Pharm Sci Pharmacol. 2014 Jun 1;1(2):87-100.

10.

Self-assembled FUS binds active chromatin and regulates gene transcription.

Yang L, Gal J, Chen J, Zhu H.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17809-14. doi: 10.1073/pnas.1414004111. Epub 2014 Dec 1.

11.

Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis.

Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y.

J Biol Chem. 2014 Jan 10;289(2):1192-202. doi: 10.1074/jbc.M113.516492. Epub 2013 Nov 26.

12.

The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).

Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SM.

J Biol Chem. 2014 Jan 3;289(1):326-34. doi: 10.1074/jbc.M113.493874. Epub 2013 Nov 20.

13.

Functions of heterogeneous nuclear ribonucleoproteins in stem cell potency and differentiation.

Chen Q, Jin M, Zhu J, Xiao Q, Zhang L.

Biomed Res Int. 2013;2013:623978. doi: 10.1155/2013/623978. Epub 2013 Jul 29. Review.

14.

The complexity of NF-κB signaling in inflammation and cancer.

Hoesel B, Schmid JA.

Mol Cancer. 2013 Aug 2;12:86. doi: 10.1186/1476-4598-12-86. Review.

15.

FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.

Dhar SK, Zhang J, Gal J, Xu Y, Miao L, Lynn BC, Zhu H, Kasarskis EJ, St Clair DK.

Antioxid Redox Signal. 2014 Apr 1;20(10):1550-66. doi: 10.1089/ars.2012.4984. Epub 2013 Sep 20.

16.

The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage.

Mastrocola AS, Kim SH, Trinh AT, Rodenkirch LA, Tibbetts RS.

J Biol Chem. 2013 Aug 23;288(34):24731-41. doi: 10.1074/jbc.M113.497974. Epub 2013 Jul 5.

17.

The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site.

Liu X, Niu C, Ren J, Zhang J, Xie X, Zhu H, Feng W, Gong W.

Biochim Biophys Acta. 2013 Feb;1832(2):375-85. doi: 10.1016/j.bbadis.2012.11.012. Epub 2012 Nov 28.

18.

The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS.

Yamaguchi A, Kitajo K.

PLoS One. 2012;7(11):e49267. doi: 10.1371/journal.pone.0049267. Epub 2012 Nov 13.

19.

Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.

Sasayama H, Shimamura M, Tokuda T, Azuma Y, Yoshida T, Mizuno T, Nakagawa M, Fujikake N, Nagai Y, Yamaguchi M.

PLoS One. 2012;7(6):e39483. doi: 10.1371/journal.pone.0039483. Epub 2012 Jun 19.

20.

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).

Bentmann E, Neumann M, Tahirovic S, Rodde R, Dormann D, Haass C.

J Biol Chem. 2012 Jun 29;287(27):23079-94. doi: 10.1074/jbc.M111.328757. Epub 2012 May 4.

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