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Items: 14


Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.

Müller-Edenborn B, Kania G, Osto E, Jakob P, Krasniqi N, Beck-Schimmer B, Blyszczuk P, Eriksson U.

PLoS One. 2016 May 3;11(5):e0154699. doi: 10.1371/journal.pone.0154699. eCollection 2016.


Phase I safety study of ranolazine in pulmonary arterial hypertension.

Gomberg-Maitland M, Schilz R, Mediratta A, Addetia K, Coslet S, Thomeas V, Gillies H, Oudiz RJ.

Pulm Circ. 2015 Dec;5(4):691-700. doi: 10.1086/683813.


Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris.

Aldakkak M, Stowe DF, Camara AK.

Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14.


An increase in the redox state during reperfusion contributes to the cardioprotective effect of GIK solution.

Suranadi IW, Demaison L, Chaté V, Peltier S, Richardson M, Leverve X.

J Appl Physiol (1985). 2012 Sep 1;113(5):775-84. doi: 10.1152/japplphysiol.01153.2011. Epub 2012 Jul 12.


New treatment options for late Na current, arrhythmias, and diastolic dysfunction.

Maier LS.

Curr Heart Fail Rep. 2012 Sep;9(3):183-91. doi: 10.1007/s11897-012-0099-3. Review.


Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.

Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC Jr.

Circ Res. 2012 Mar 16;110(6):841-50. doi: 10.1161/CIRCRESAHA.111.258251. Epub 2012 Feb 16.


Ranolazine reduces Ca2+ overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts.

Aldakkak M, Camara AK, Heisner JS, Yang M, Stowe DF.

Pharmacol Res. 2011 Oct;64(4):381-92. doi: 10.1016/j.phrs.2011.06.018. Epub 2011 Jun 29.


Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure.

Undrovinas NA, Maltsev VA, Belardinelli L, Sabbah HN, Undrovinas A.

J Physiol Sci. 2010 Jul;60(4):245-57. doi: 10.1007/s12576-010-0092-0. Epub 2010 May 19.


Chick embryo partial ischemia model: a new approach to study ischemia ex vivo.

Majumder S, Ilayaraja M, Seerapu HR, Sinha S, Siamwala JH, Chatterjee S.

PLoS One. 2010 May 7;5(5):e10524. doi: 10.1371/journal.pone.0010524.


Mechanism of action of the new anti-ischemia drug ranolazine.

Hasenfuss G, Maier LS.

Clin Res Cardiol. 2008 Apr;97(4):222-6. Epub 2007 Nov 28. Review.


Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects.

Schram G, Zhang L, Derakhchan K, Ehrlich JR, Belardinelli L, Nattel S.

Br J Pharmacol. 2004 Aug;142(8):1300-8. Epub 2004 Jul 26.


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